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PedAM

Pediatric Disease Annotations & Medicines




Disease anoxia
Phenotype C0022116|ischaemia
Sentences 8
PubMedID- 24098804 [22] this negative results in patients after ischaemic stroke and traumatic brain injury underline the difficulty in comparing focal ischaemia with global hypoxia after cardiac arrest as stated before.
PubMedID- 25922643 Similarly in pathological settings, for example, when hypoxia correlates with retinal ischaemia, the imbalance between ros production and the ability to scavenge these ros by endogenous antioxidant systems may also be exacerbated.
PubMedID- 23407685 In which bilateral cerebral ischaemia occurred because of hypoxia which followed an intervention to replace an aortic valve [9].
PubMedID- 22106416 Methods and results: adult rat cardiomyocytes were subjected to simulated in vitro ischaemia (si) consisting of glucose-free anoxia at ph 6.4.
PubMedID- 26054890 Notably, the myocardium and epicardial fat share the same vasculature; therefore, the presence of myocardial ischaemia may provoke hypoxia of cardiac fat depot, prompting an inflammatory reaction within the eat resulting in an unfavourable anti-inflammatory/pro-inflammatory metabolic condition with the subsequent secretion of vasoconstrictive and pro-inflammatory cytokines [41].
PubMedID- 26019818 ischaemia can lead to overexpression of hypoxia-inducible factor-1α (hif-1α) [11].
PubMedID- 25626888 Background: patients undergoing neurosurgery are at risk of cerebral ischaemia with resultant cerebral hypoxia and neuronal cell death.
PubMedID- 25807115 [64] hypoxia, in association with ischaemia and/or infection, is also thought to play a role in the aetiology of cerebral palsy and epilepsy.

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