PedAM

Pediatric Disease Annotations & Medicines

Disease	anoxia
Phenotype	C0020538\|hypertension
Sentences	27
PubMedID- 24429505	Cerebral hypotension and hypoxia were associated with postoperative intracranial hypertension (p = 0.02 and 0.03, respectively).
PubMedID- 22937913	However brachycephalic dogs may be predisposed to pulmonary hypertension, due to chronic hypoxia, and dogs with pulmonary hypertension can have increased concentrations of ctni [40].
PubMedID- 20811560	Areas of emphysema cause an increased pulmonary vascular resistance due to alveolar hypoxia leading to pulmonary hypertension [12].
PubMedID- 21652603	Although intermittent hypoxia is often associated with hypertension, experimental and clinical studies have demonstrated definite antihypertensive effects of some intermittent hypoxia conditioning (ihc) regimens.
PubMedID- 24024204	It is widely believed that the pulmonary hypertension associated with chronic hypoxia is due more to vascular remodelling, hypervolaemia, polycythaemia, and increased blood viscosity rather than hpv per se.
PubMedID- 21884511	Iron homeostasis influences the development of pulmonary arterial hypertension (pah) associated with hypoxia or hematologic disorders.
PubMedID- 22291752	We hypothesise that the combination of small vessel disease secondary to diabetes and hypertension, together with hypoxia secondary to untreated sleep apnea might have been the cause of the patient’s ischemic events.
PubMedID- 22518182	If not recognized and managed, chronic hypoxia can lead to pulmonary hypertension and cor pulmonale.
PubMedID- 22754566	As microvascular damage and hypertension are strongly associated with intermittent ischemia, hypoxia, and ad-related pathology, it seems likely that the cerebrovascular activity of the egfr is an important aspect of its role in neurodegenerative pathophysiology.
PubMedID- 25745471	Pulmonary hypertension is associated with hypoxia and the formation of so-called plexiform lesions.
PubMedID- 26564080	The sequelae of visceral organ involvement include ischemic stroke, cerebral bacterial abscesses, intracranial hemorrhage, chronic hypoxia, dyspnea with exertion, pulmonary hypertension, high output heart failure, gastrointestinal bleeds and liver failure.
PubMedID- 22837861	[1213] pulmonary hypertension associated with chronic hypoxia has been directly linked to an imbalance between glycolysis, glucose oxidation, and fatty acid oxidation.
PubMedID- 26440165	Pulmonary arterial hypertension due to hypoxia-induced pulmonary vascular remodeling is the predominant cause of right-sided congestive heart failure (chf) in cattle.
PubMedID- 25217498	The human pulmonary circulation loses its natural distensibility during sustained hypoxia, leading to pulmonary arterial hypertension and a much higher workload for the right ventricle.
PubMedID- 22965765	Patients with asthma develop pulmonary hypertension due to recurrent hypoxia and chronic inflammation, leading to right heart enlargement with ventricular hypertrophy.
PubMedID- 21890893	We demonstrate here that sirt1 is targeted in macrophages by chronic hypoxia, which is associated with pulmonary hypertension (hph) and chronic obstructive pulmonary disease (copd) and oxldl, a primary risk factor for atherosclerosis.
PubMedID- 20532059	In patients who concurrently have hypoxic pulmonary vasoconstriction (hpv) and pulmonary hypertension due to alveolar hypoxia, such as ards, no has been used as a supplemental treatment agent when hypoxemia is not resolved with oxygen supply and the appropriate mechanical ventilation.
PubMedID- 24499246	In support of this notion, these authors reported an enhanced pulmonary vascular reactivity to hypoxia in patients with uncomplicated systemic hypertension [3].
PubMedID- 23658499	More specifically, hypertension may lead to hypoperfusion, or hypoxia of the brain, which can lead to ad pathology.110,118 individuals who underwent antihypertensive treatment had lower neuritic plaques and neurofibrillary tangles than controls.119 hypertension also has an effect on the blood–brain barrier, leading to inflammation or the accumulation of β-amyloid, causing the development of ad.
PubMedID- 24734153	It is well established that oxygen sensing by the carotid body plays an important role in the development of systemic hypertension associated with intermittent hypoxia and osa [93].
PubMedID- 23950890	In addition, hypoxia can provoke hypertension through diverse mechanisms mediated by hif-1α [56] and leading to increased levels of catecholamines [57].
PubMedID- 23181475	hypertension leads to renal hypoxia, mediated by increased angiotensin receptor tonus and oxidative stress.
PubMedID- 25847058	Objective: although several micrornas were reported to play essential roles in pulmonary artery hypertension due to hypoxia or monocrotaline, their potential role in pulmonary arterial hypertension secondary to congenital heart disease is largely unknown.
PubMedID- 26575340	The human pulmonary circulation loses its natural distensibility during sustained hypoxia, leading to pulmonary arterial hypertension and a much higher workload for the right ventricle.
PubMedID- 20427574	Pasmcs have been suggested to be particularly sensitive to oxygen availability and to be responsible for acute hypoxic vasoconstriction and the development of pulmonary hypertension due to chronic hypoxia (weir et al., 2005; aaronson et al., 2006; stenmark et al., 2006; gupte and wolin, 2008).
PubMedID- 21246034	Background: the present study investigated whether changes in gene expression in the right ventricle following pulmonary hypertension can be attributed to hypoxia or pressure loading.
PubMedID- 20110569	Dynamic changes in lung microrna profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline.

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