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PedAM

Pediatric Disease Annotations & Medicines




Disease anoxia
Phenotype C0018801|heart failure
Sentences 7
PubMedID- 22802226 We described recently that systemic hypoxia provokes vasoconstriction in heart failure (hf) patients.
PubMedID- 24748865 The patient died from congestive heart failure with anoxia 38 days after admission.
PubMedID- 22167142 Objectives: the hemolysis of red blood cells due to isoimmunisation results in fetal anaemia and hypoxia leading to fetal heart failure.
PubMedID- 25645252 Therefore, the non-invasive determination of oxygenation within the intact heart may shed light on the important question whether the development of cardiac hypertrophy and the subsequent transition to heart failure is associated with increased hypoxia or suppressed mitochondrial energy production.
PubMedID- 22046218 Metformin works primarily in the liver to decrease glucose production from lactate, among other substances; it has therefore been theorized that metformin could cause the accumulation of lactate under certain metabolic conditions such as the substantial tissue hypoperfusion and hypoxia observed in patients with acute heart failure.
PubMedID- 23739952 heart failure is accompanied with tissue (circulatory) hypoxia, and the metabolism of several drugs has been reported to be reduced in heart failure.
PubMedID- 21912722 [98] showed that the transfer of adenoviral cuznsod (ad cuznsod) gene to the carotid body increased cuznsod protein expression and reduced the baseline renal sympathetic nerve activity (rsna) and the response of rsna to hypoxia in rabbits with chronic heart failure.

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