PedAM
Pediatric Disease Annotations & Medicines
| Disease | anoxia |
| Phenotype | C0011847|diabetes |
| Sentences | 12 |
| PubMedID- 21614571 | diabetes is frequently associated with hypoxia and is known to impair ischaemia-induced neovascularisation and other forms of adaptive cell and tissue responses to low oxygen levels. |
| PubMedID- 24055447 | Aims: although accumulating evidence suggests the associations between sleep apnea syndrome (sas) and type 2 diabetes, the direct effect of intermittent hypoxia (ih) on pancreatic beta cell proliferation remains a missing piece of the puzzle. |
| PubMedID- 23536585 | Obstructive sleep apnea is another cause of hypoxia, particularly in patients with type 2 diabetes (9). |
| PubMedID- 23619295 | Using genome-wide expression profiling, we previously demonstrated that exposure to maternal diabetes resulted in dysregulation of the hypoxia-inducible factor 1 (hif-1) pathway in the developing embryo. |
| PubMedID- 22513875 | As the lens is located in the hypoglycemic environment under hypoxia, aging lens with diabetes might aggravate these stresses. |
| PubMedID- 22991450 | Renal hypoxia in diabetes is due to a reduction of oxygen delivery (5) and also to an increase in oxygen consumption at least partially secondary to an increase of respiratory uncoupling (6). |
| PubMedID- 20079805 | Effect of virgin olive oil plus acetylsalicylic acid on brain slices damage after hypoxia-reoxygenation in rats with type 1-like diabetes mellitus. |
| PubMedID- 22566988 | Data on arm power, atrial fibrillation, abnormal physiological features, diabetes, history of coronary heart disease, hypoxia, hypertension, leg power, maximum systolic blood pressure, minimum systolic blood pressure, pyrexia, hyperglycaemia, previous stroke, previous transient ischaemic attack, smoking status, alcohol intake, osmolarity and verbal score were missing in 0.1–33.4% of the patients. |
| PubMedID- 22254144 | Many of the environmental risk factors associated with alzheimer's disease, including infectious agents (herpes simplex, chlamydia pneumonia, and borrelia burgdorferi) as well as vitamin a deficiency, hypercholesterolaemia, hyperhomocysteinaemia or folate deficiency, oestrogen depletion, cerebral nerve growth factor (ngf) deprivation, diabetes, cerebral hypoperfusion (leading to hypoxia and hypoglycaemia) or are able to promote cerebral beta-amyloid deposition (in the absence of any particular gene variant) in animal models [1]. |
| PubMedID- 22302938 | Dietary obesity is a major factor in the development of type 2 diabetes and is associated with intra-adipose tissue hypoxia and activation of hypoxia-inducible factor 1alpha (hif1alpha). |
| PubMedID- 26137497 | diabetes mellitus can lead to retinal tissue hypoxia and dysregulation of immune responses in the retinal tissue. |
| PubMedID- 23364451 | With consideration of a key role of reduced nerve blood flow and endoneurial hypoxia in diabetes-induced mncv and sncv deficits (6–8,13), and of involvement of er stress in other diabetic microvascular complications, such as nephropathy (29) and retinopathy (30), future studies should dissect the role for er stress/upr in neurovascular dysfunction associated with diabetes. |
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