PedAM
Pediatric Disease Annotations & Medicines
| Disease | anoxia |
| Phenotype | C0011570|depression |
| Sentences | 15 |
| PubMedID- 26486366 | This response was likely attributable to a rapid anoxia-induced depression of aerobic atp-production pathways followed by an up-regulation of anaerobic atp-production pathways such that the atp production rate was restored to that measured in normoxia. |
| PubMedID- 21569387 | Increases in gaba as a consequence of brain hypoxia can lead to depression of ventilation, which becomes more apparent in the absence of peripheral chemoreceptors. |
| PubMedID- 24028507 | This method confers rapid loss of consciousness in response to hypoxia attributed to depression of vital centers and is performed in a carbon dioxide chamber. |
| PubMedID- 24517264 | Eight cases were due to an overdosage of the drug; for the other 19, three specific causes were identified: opioid accumulation due to a renal insufficiency that had been overlooked; patients who were hyper-metabolizers; and codeine therapy used for patients who had tonsillectomy and/or adenoidectomy for recurrent obstructive sleep apnea or tonsillitis (and whose respiratory depression probably coincided with a hypoxia that exacerbated their susceptibility to a drug-related respiratory depression. |
| PubMedID- 25803141 | Hypobaric hypoxia induces depression-like behavior in female sprague-dawley rats, but not in males. |
| PubMedID- 23319379 | Since the role of heroin in respiratory depression with consequent hypoxia is known, the authors were able to investigate morphological and molecular modifications occurring in the cb of heroin addicted subjects compared to subjects who died because of trauma. |
| PubMedID- 24256627 | In addition, hypoxia may lead to a depression of hypoxic ventilatory responsiveness, leading to reduced ventilation and reduced co2 elimination, both between apneas and in daytime [68]. |
| PubMedID- 21364989 | Furthermore, it is known that hypoxia leads to cortical spreading depression in neuronal circuits, which significantly disrupts bbb integrity [38]. |
| PubMedID- 22994218 | During the subacute phase, the irreversible damage expands into the penumbra: multiple electrical and biological signals are triggered by periinfarct, spreading depression-like depolarizations leading to hypoxia and stepwise increase in lactate. |
| PubMedID- 24138959 | Although the pathology of wmhs varies, autopsy studies have shown that they are associated with ischemic damage and tissue hypoxia in patients with late-life major depression [9]. |
| PubMedID- 25730991 | Thus, keeping the animals in constant darkness after the modeling of acute hypoxia leads to the depression of locomotive and exploratory components of the behavior. |
| PubMedID- 21756983 | In addition, propofol indirectly induced apoptosis through hypoxia resulting from respiratory depression under air or hypoxic conditions, which was determined by elevated expression of caspase-3, increased tunel-positive cells, ultrastructural changes of neuronal cell death and loss of nissl staining neuronal in infant sd rat brains. |
| PubMedID- 26088333 | hypoxia was associated with the depression of both lfmod and hfmod component. |
| PubMedID- 21458539 | Our results suggest that brief hypoxia-induced depression of the glutamate receptor-mediated [ca(2+)](i) responses contributes to the development of rapid hypoxic preconditioning in hippocampal ca1 neurons. |
| PubMedID- 22211853 | Background: methadone intoxication can cause respiratory depression, leading to hypoxia with subsequent coma and death. |
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