Disease | anoxia |
Phenotype | C0007134|renal cell carcinoma |
Sentences | 3 |
PubMedID- 20008644 | Purpose: inactivation of the von hippel-lindau gene in clear-cell renal cell carcinomas (rcc) leads to overexpression of hypoxia inducible factor, a transcription factor regulating vascular endothelial growth factor (vegf) and platelet-derived growth factor (pdgf) gene expression. |
PubMedID- 23206420 | A possible role for microrna-141 down-regulation in sunitinib resistant metastatic clear cell renal cell carcinoma through induction of epithelial-to-mesenchymal transition and hypoxia resistance. |
PubMedID- 23940778 | Proteomic analysis of signaling network regulation in renal cell carcinomas with differential hypoxia-inducible factor-2alpha expression. |
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