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PedAM

Pediatric Disease Annotations & Medicines




Disease anaplastic large cell lymphoma
Phenotype C0026986|myelodysplastic syndrome
Sentences 2
PubMedID- 22246491 Leukemic presentation of alk-negative anaplastic large cell lymphoma in a patient with myelodysplastic syndrome.
PubMedID- 20877721 Npm1 fusion proteins are also specifically involved: t(5;17)(q35;q21)/npm1-rara causes acute promyelocytic leukemia; t(2;5)(p23;q35)/npm1-alk underlies anaplastic large cell lymphoma; t(3;5)(q26;q35)/npm1-mlf1 is associated with myelodysplastic syndromes (mds) and aml with trilineage dysplasia and poor prognosis (http://atlasgeneticsoncology.org).

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