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PedAM

Pediatric Disease Annotations & Medicines




Disease alopecia
Phenotype C0033300|progeria
Sentences 1
PubMedID- 26027936 Mtdna integrity is also required for proper stem cell function: “mtdna mutator” mice, which accumulate random mtdna mutations in all tissues, including sscs, develop progeria, with gray hair, alopecia, osteoporosis, general wasting, anemia, reduced fertility, and shortened lifespan (ameur et al., 2011; kujoth et al., 2005; trifunovic et al., 2004).

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