PedAM
Pediatric Disease Annotations & Medicines
| Disease | alcohol abuse |
| Phenotype | C0042373|vascular disease |
| Sentences | 4 |
| PubMedID- 22661894 | Consistent evidence associates increased circulating serum gamma-glutamyltransferase (ggt), a parameter conventionally used for diagnosing hepatobiliary diseases and alcohol abuse,1 with incident cardiovascular disease (cvd)2 and major proatherogenic risk factors.3 for this reason, ggt determination has been added to the array of biomarkers useful for stratifying cardiometabolic risk.4 furthermore, the enzyme’s active involvement in the atherogenic process was hypothesized on the basis of its potential to increase the intracellular prooxidant burden through the iron-reducing properties of cysteinylglycine moieties generated during ggt-catalyzed glutathione hydrolysis.5 the identification of prooxidant ggt activity in atheromatous plaques of carotid and coronary arteries6 adds to the need for further clinical evaluation. |
| PubMedID- 21970791 | The exclusion criteria consisted of: any relapse with corticosteroid treatment at the time or within one month preceding study entry or mri examination, pre-existing medical conditions known to be associated with brain pathology (e.g., neurodegenerative disorders, cerebrovascular disease, positive history of alcohol abuse, etc. |
| PubMedID- 24139135 | Exclusion criteria for the premise study at screening were: an acute relapse, disease progression and/or steroid treatment within 30 days preceding study entry, pre-existing medical conditions known to be associated with brain pathology (e.g., neurodegenerative disorder, cerebrovascular disease, positive history of alcohol abuse), severe peripheral chronic venous insufficiency, severe contrast media allergy (anaphylaxis) and abnormal renal function. |
| PubMedID- 22870210 | Exclusion criteria for both patients and controls were preexisting medical conditions known to be associated with brain pathology (e.g., cerebrovascular disease, positive history of alcohol abuse), history of cerebral congenital malformations, thrombosis of jugular veins, deep venous thrombosis, central venous catheter, head and neck surgery, transient global amnesia, vasculitis and pregnancy. |
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