PedAM
Pediatric Disease Annotations & Medicines
| Disease | alcohol abuse |
| Phenotype | C0020538|hypertension |
| Sentences | 5 |
| PubMedID- 24342112 | For social phobia and alcohol abuse, associations with hypertension were stronger for males than females. |
| PubMedID- 24235878 | Even underreporting alcohol consumption or the white coat effect, the association of alcohol abuse with hypertension has been confirmed by ambulatory monitoring of blood pressure [38]. |
| PubMedID- 22606372 | On the other hand, chronic alcohol abuse is associated with hypertension in animals and humans [45] and pharmacological (high) doses of ethanol induce vasoconstriction in aortic ring studies via redox-sensitive and cyclooxygenase-dependent signaling [60]. |
| PubMedID- 20716942 | In addition, alcohol abuse leads to hypertension, cardiac arrhythmias, and nonischemic cardiomyopathy.92 consequential reductions in cardiac output would lead to liver injury due to chronic passive congestion, and also exacerbate injurious effects of chronic ethanol exposure or acetaldehyde formation. |
| PubMedID- 24288753 | Cyp2e1 gene promoter polymorphism -1293g>c increases the risk of essential hypertension in men with alcohol abuse. |
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