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PedAM

Pediatric Disease Annotations & Medicines




Disease adenocarcinoma
Phenotype C0220650|brain metastasis
Sentences 11
PubMedID- 26400668 The brain metastasis of case 3 was adenocarcinoma without t790m mutation or met amplification.
PubMedID- 24433734 [secretory adenocarcinoma of lung with brain metastasis: report of a case].
PubMedID- 24450263 Histologically and immunohistohemically, the diagnosis of primary lung adenocarcinoma with brain metastasis was made (tumor cells showed positivity for ck7 and ttf-1 which confirmed the diagnosis).
PubMedID- 26469914 However, the efficacy of afatinib, the second-generation irreversible egfr tki, as the first-line treatment in lung adenocarcinoma patients with brain metastasis has yet to be evaluated.
PubMedID- 25453849 Materials and methods: we analyzed retrospectively 292 lung adenocarcinoma patients with brain metastasis.
PubMedID- 26050023 To explore the correlation between epidermal growth factor receptor (egfr) mutation status and the risk of brain metastasis (bm) in patients with lung adenocarcinoma, the clinical data of 100 patients with pathologically confirmed lung adenocarcinoma and known egfr mutation status at exon 18, 19, 20, or 21 were analyzed retrospectively.
PubMedID- 26396124 Cerebral imaging revealed a solitary cerebral mass that was radiologically felt to be a primary brain tumour, but a brain biopsy demonstrated an adenocarcinoma in keeping with brain metastasis.
PubMedID- 24212826 Therefore, egfr-tkis may play an important role in the management of lung adenocarcinoma with brain metastasis [35,36].
PubMedID- 21992608 Du-145, a cell line originally derived from a brain metastasis of a human prostate adenocarcinoma [46] retains the androgen independence of the original tumor and does not express a functional ar [47].
PubMedID- 25963555 Similarly, a brain metastasis of a poorly differentiated adenocarcinoma of the lung was established as a pdx tumor of a poorly differentiated adenocarcinoma (fig.
PubMedID- 25726044 Occurrence rates of brain metastasis were higher in patients with adenocarcinoma or those with a high pt and pn stage.

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