PedAM

Pediatric Disease Annotations & Medicines

Disease	adenocarcinoma
Phenotype	C0028754\|obesity
Sentences	11
PubMedID- 20596708	Underweight patients mostly suffered from squamous cell carcinoma (55%), whereas the majority of patients with normal weight, overweight, or obesity was diagnosed with adenocarcinoma (89%; p < 0.001).
PubMedID- 24495751	Finally, but it’s not trivial, there is a very clear association of obesity with the adenocarcinoma of the oesophagus.
PubMedID- 20632267	Background: obesity is associated with oesophageal adenocarcinoma, but mechanisms linking fat and carcinogenesis remain poorly understood.
PubMedID- 22972011	Background: esophageal adenocarcinoma is often associated with obesity, and a 5 kg m(-2) increase in body mass index (bmi) has, in fact, been found to be strongly associated with the risk of this type of cancer (rr, 1.52; p < 0.0001).
PubMedID- 22121096	Mmp9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation.
PubMedID- 23819063	Some evidence from cohorts and meta-analysis has recently confirmed the association between obesity and risk of esophageal adenocarcinoma [147, 314, 315].
PubMedID- 25598323	General and abdominal obesity and risk of esophageal and gastric adenocarcinoma in the european prospective investigation into cancer and nutrition.
PubMedID- 22102975	Another study said that obesity was related with an adenocarcinoma of the gastric cardia [30].
PubMedID- 22969802	Prior studies have indicated the positive link between dietary fat as well as obesity and the risk of oesophageal adenocarcinoma [43–45], but little evidence has been reported regarding the role of serum lipids.
PubMedID- 25269698	obesity and risk of esophageal adenocarcinoma and barrett's esophagus: a mendelian randomization study.
PubMedID- 25364384	Several possible mechanisms could link obesity with the risk of oesophageal adenocarcinoma in addition to mechanical effects increasing reflux.

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