PedAM
Pediatric Disease Annotations & Medicines
| Disease | adenocarcinoma |
| Phenotype | C0017168|esophageal reflux |
| Sentences | 15 |
| PubMedID- 23349988 | The main risk factors for oesophageal squamous cell carcinoma in industrialised countries are tobacco smoking and alcohol abuse, while adenocarcinoma is mainly associated with gastro-oesophageal reflux and obesity [4]. |
| PubMedID- 24282412 | Progression from healthy tissue to premalignant barrett's oesophagus (bo) and further to malignant oesophageal adenocarcinoma (oac) is associated with gastro-oesophageal reflux, leading to ros accumulation and increased oxidative dna damage. |
| PubMedID- 25998241 | For instance, it was shown that an ability to visualize nanoscale structures might be critical for early detection of various cancers, such as ovarian cancer, which is the fifth leading cause of death due to cancer in women1, or adenocarcinoma in patients with chronic gastroesophageal reflux disease2. |
| PubMedID- 24073332 | In fact, whether oesophageal reflux is associated with adenocarcinoma [10], or whether it is favoured by obesity [11], the change in oesophageal cancer morphology from squamous to adenocarcinoma has followed the worldwide rise in obesity. |
| PubMedID- 24243140 | Siewert and leers have previously reported 37% 2 and 50% 3 respectively from large single centre western series compared to the low prevalence of type iii tumours seen in eastern series (5.6%) 29. the proportional increase in type i tumours in our series is likely to represent the widely reported increase in incidence of oesophageal adenocarcinoma 30,31 associated with gastro-oesophageal reflux disease 32 and barrett's metaplasia 33 in the united kingdom 34. the expansion of endoscopic barrett's surveillance strategies is also likely to have increased disease detection and treatment. |
| PubMedID- 21636532 | Gastroesophageal reflux is associated with adenocarcinoma in barrett's esophagus, but the incidence of this tumor is rising, despite widespread use of acid-suppressing medications. |
| PubMedID- 21953142 | Gastric tube reconstruction reduces postoperative gastroesophageal reflux in adenocarcinoma of esophagogastric junction. |
| PubMedID- 21484485 | Introduction: esophageal adenocarcinoma is aetiologically associated with gastro-esophageal reflux, but the mechanisms responsible for the metaplasia-dysplasia sequence are unknown. |
| PubMedID- 23180455 | Oesophageal adenocarcinoma is associated with gastro-oesophageal reflux disease, obesity and the precursor lesion barrett's oesophagus; its incidence has increased faster than that of any other cancer in the usa in the past few decades.2 oesophageal squamous cell carcinoma is associated with tobacco smoking, alcohol consumption and poor nutrition; its incidence remains much higher than that of oesophageal adenocarcinoma in most of the world.3 patients with oesophageal cancer continue to have a poor prognosis, with 5-year overall survival still less than 15%.4 a greater understanding of the molecular basis of oesophageal cancer, including the development of new biomarkers, is greatly needed to improve the diagnosis, prognosis and treatment of patients with this disease. |
| PubMedID- 24212953 | With duodenoesophageal reflux, 50% of tumors were adenocarcinoma, in contrast to 100% squamous differentiation of tumors in rats given the carcinogens with esophagogastroplasty, which was supposed to induce gastric reflux alone, or no operation. |
| PubMedID- 26269688 | Barrett's esophagus (be) is a precursor of esophageal adenocarcinoma and is associated with gastroesophageal reflux disease, which is often preceded by a hiatal hernia. |
| PubMedID- 24968432 | The incidence of esophageal adenocarcinoma is strongly associated with that of gastro-esophageal reflux disease (gerd). |
| PubMedID- 20955441 | Meta-analysis: the association of oesophageal adenocarcinoma with symptoms of gastro-oesophageal reflux. |
| PubMedID- 23225453 | Background: esophageal adenocarcinoma results from gastroesophageal reflux and develops along a sequence involving non-dysplastic barrett's esophagus (ndbe), low- (lgd) and high-grade dysplasia (hgd). |
| PubMedID- 24084597 | Background: the mechanisms of esophageal reflux leading to esophageal adenocarcinoma (ea) remain poorly understood. |
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