PedAM
Pediatric Disease Annotations & Medicines
| Disease | acute leukemia |
| Phenotype | C0024305|non-hodgkin\'s lymphoma |
| Sentences | 1 |
| PubMedID- 23323114 | Specificity of ca-125 was low, and its increase has been observed in various neoplastic and non-neoplastic conditions: ovarian malignancies, acute leukemia with extramedullary localization, non-hodgkin's lymphoma, melanomas, breast, lung, or gastrointestinal carcinomas, abdominal surgery, bacterial peritonitis, pelvic inflammatory disease, or tuberculosis.14 unlike ca-125, serum pth-related peptide is regarded as a useful indicator of tumor-related hypercalcemia and bone metastasis of solid tumor and hematologic malignancies.15 however, production of pth-related peptide has also been reported in nonneoplastic tissues and several endocrine glands, including non-tumorous thyroid follicular epithelium, colloid nodules, non-tumorous testicular leydig cells, normal ovarian granulosa-theca cells, placental trophoblast, deciduas, and normal adrenal cortex.16 as observed in our case, elevated ca-125 and pth-related peptide might be a compensatory physiologic response to pleural effusion and hypoparathyroidism. |
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