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PedAM

Pediatric Disease Annotations & Medicines




Disease achalasia
Phenotype C0032298|lipoid pneumonia
Sentences 1
PubMedID- 24633206 Infections with non-tuberculous mycobacteria (ntm) have become a growing clinical concern over the past two decades due to their association with aids, recognition of the increasing incidence of ntm infections among patients without aids and the multidrug-resistant nature of some of the organisms.1,2 besides aids, predisposing factors for clinically significant ntm infection include immunosuppressive conditions (transplantation, chronic corticosteroid use, malignancies), structural lung disease (chronic obstructive pulmonary disease, bronchiectasis, cystic fibrosis), tumour necrosis factor-α blocking agents (infliximab, adalimumab, etanercept, golimumab, certolizumab), body morphotype, immunological defects due to genetic causes (mutations in interferon-γ and interleukin-12 pathways) and oesophageal motility disorders such as achalasia complicated by lipoid pneumonia.2–7 the ntm infections also have been associated with use of medical devices (e.g.

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