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PedAM

Pediatric Disease Annotations & Medicines




Disease acanthosis nigricans
Phenotype C0028754|obesity
Sentences 6
PubMedID- 22345779 [2] based on clinical characteristics schwartz divided an into eight types: benign an, pseudo acanthosis nigricans connected with obesity, syndromic an, paraneoplastic, malignant an, acral an, unilateral an, drug-induced an and mixed an.
PubMedID- 25396121 The serendipitous finding of palmar freckles/melanotic macules in type 1 neurofibromatosis- yesudian et al.’ sign,[22] the finding of cerebriform tongue as a clinical sign in pemphigus vegetans,[23] the characteristic diagnostic cutaneous features of pentazocine-induced ulcers,[24] facial acanthosis nigricans associated with obesity,[25] contact depigmentation occurring from free para-tertiary-butylphenol in bindi adhesive,[26] the pattern of frictional sweat dermatitis,[2728] dermatitis on the knee following knee replacement[29] are all examples of rare but important conditions highlighted by case reports and case series.
PubMedID- 22287962 These factors included age, central obesity, presence of acanthosis nigricans, and dyslipidemia.
PubMedID- 23329743 Ir (13.5%) was higher among those with moderate-to-severe obesity, in patients with acanthosis nigricans and was associated with other cardiovascular disease risk factors.
PubMedID- 23259085 acanthosis nigricans associated with morbid obesity and colorectal adenocarcinoma.
PubMedID- 22898282 Conclusions: childhood benign acanthosis nigricans is closely associated with obesity, insulin resistance and dyslipidemia.

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