PedAM
Pediatric Disease Annotations & Medicines
| Disease | c syndrome |
| Phenotype | |obesity |
| Sentences | 377 |
| PubMedID- 22662254 | Transgenic over-expression of 11β-hsd1 in adipose tissue recapitulates the metabolic syndrome in mice, with visceral obesity, dyslipidemia, insulin resistance/diabetes and hypertension [2], [5]. |
| PubMedID- 21799635 | The key risk factors that need to be controlled in the perimenopausal woman are hypertension, dyslipidemia, obesity, and other components of the metabolic syndrome, with the careful control of diabetes. |
| PubMedID- 21147642 | The prevalence of the pediatric metabolic syndrome in children with obesity is growing much more rapidly in developing countries than in industrialized countries [37]. |
| PubMedID- 20061420 | obesity without established comorbidities of the metabolic syndrome is associated with a proinflammatory and prothrombotic state, even before the onset of puberty in children. |
| PubMedID- 23497697 | obesity and diet-dependent development of metabolic syndrome are considered as a global health problem [1,2]. |
| PubMedID- 23781121 | During the last decade it has been extensively demonstrated that risk factors of metabolic syndrome often associated with obesity, characterized by macrophage infiltration and activation in adipose tissue and liver can be treated by ppars targets [18]. |
| PubMedID- 23865483 | Particularily abdominal obesity has been associated with metabolic syndrome [68], pre-clinical atherosclerosis [69], cardiovascular events [70] and mortality [70]. |
| PubMedID- 21935443 | Variations caused by il-6 promoter polymorphisms are associated with diabetes mellitus, obesity and several features of the metabolic syndrome [9]. |
| PubMedID- PMC4150581 | (central) obesity is a hallmark of the metabolic syndrome of which the other components are: dyslipidaemia, hypertension, impaired glucose metabolism, with insulin resistance and diabetes type 2. particularly if poorly controlled, there is a significant association between low level of total testosterone or dhea-s and indices of poorly controlled type 2 diabetes. |
| PubMedID- 22150400 | This association was mainly driven by the central obesity component of the metabolic syndrome. |
| PubMedID- 26064845 | In fact, insulin resistance, dyslipidemia, obesity and hypertension, each of these variables of metabolic syndrome gets influenced by the serum uric acid level. |
| PubMedID- 26096168 | Metabolic syndrome is characterized with abdominal obesity, insulin resistance, dyslipidemia and hepatic dysfunction. |
| PubMedID- 21525818 | Most patients with nafld have risk factors such as insulin resistance, obesity or other indications of metabolic syndrome. |
| PubMedID- 22043170 | Despite its rarity, there is considerable interest in understanding the molecular basis and biochemical pathways of alström syndrome as a monogenic model for metabolic syndrome with obesity, insulin resistance, diabetes mellitus, hypertriglyceridemia and hypertension as common features. |
| PubMedID- 22537054 | The numbers of positive components in metabolic syndrome between subjects with central obesity and without central obesity. |
| PubMedID- 24467470 | The key search terms were bipolar disorder and metabolic syndrome cross-referenced with gender, sex, obesity, diabetes mellitus, hypertension, and dyslipidemia. |
| PubMedID- 21276250 | This would be relevant to many developing countries with poor resources, such as those in south asia, which are battling rapid increases in diabetes, obesity and other components of the metabolic syndrome. |
| PubMedID- 24829483 | The discovery that mice harboring a mutation in the core circadian gene circadian locomotor output cycles kaput (clock) develop obesity and evidence of the metabolic syndrome represented a seminal moment for the field, clearly establishing a link between circadian rhythms, energy balance, and metabolism at the genetic level. |
| PubMedID- 24130367 | Hence, excess mortality in type 2 diabetes has also been attributed to traditional risk factors, such as obesity and other components of the metabolic syndrome (6,7), and to socioeconomic factors (8). |
| PubMedID- 20836727 | These patients share common features like obesity with metabolic syndrome. |
| PubMedID- 25961053 | In contrast to the zdf male, the male zdsd rat maintains a moderately long period (approximately eight weeks) of prediabetic metabolic syndrome with obesity, followed by progression to overt diabetes and its complications. |
| PubMedID- 21754922 | Ffas cause insulin resistance in all major insulin target organs (skeletal muscle, liver, and endothelial cells) and have emerged as a major link between obesity, the development of the metabolic syndrome, and atherosclerotic vascular disease [11]. |
| PubMedID- 25646773 | Nafld refers to a spectrum of hepatic disorders secondary to an increase in hepatic triglyceride (tg) content in the setting of the metabolic syndrome that is associated with obesity, hypertension, hyperlipidemia and type ii diabetes [2]. |
| PubMedID- 23223931 | It is epidemiologically established that obesity is frequently associated with the metabolic syndrome and poses an increased risk for the development of type 2 diabetes mellitus and cardiovascular disease. |
| PubMedID- 25013207 | obesity is the hallmark of the metabolic syndrome that represents a cluster of different disorders which predispose people for the development of chronic metabolic diseases including t2dm and cardiovascular diseases [34]. |
| PubMedID- 23762536 | Abdominal obesity is one component of the metabolic syndrome [1]. |
| PubMedID- 24864249 | obesity, as part of the metabolic syndrome, is one of the major risk factors in the development of fatty liver [1, 2]. |