PedAM
Pediatric Disease Annotations & Medicines
| Disease | c syndrome |
| Phenotype | |obesity |
| Sentences | 377 |
| PubMedID- 21378565 | Purpose of review: the metabolic syndrome incorporating obesity, hypertension, dyslipidaemia and elevated plasma glucose has reached epidemic proportions in many western countries leading to a dramatic increase in insulin resistance, steatosis and type 2 diabetes. |
| PubMedID- 21277789 | Women of reproductive age are not spared from the complications of metabolic syndrome, which overlaps with obesity and polycystic ovary syndrome (pcos), both of which are linked to infertility and poor reproductive outcome. |
| PubMedID- 24265520 | Another current hypothesis proposes that obesity is associated with metabolic syndrome, which activates molecular processes that are mitogenic in breast epithelial cells and stimulates neoplasia. |
| PubMedID- 20972515 | Urbanisation is associated with obesity, hypertension and development of the metabolic syndrome (ms). |
| PubMedID- 24321125 | obesity is strongly associated with metabolic syndrome, which is characterized by the presence of insulin resistance, hypertension, and hyperlipidemia. |
| PubMedID- 21562062 | Relationships among insulin resistance, obesity, diagnosis of the metabolic syndrome and cardio-metabolic risk. |
| PubMedID- 22814837 | Conclusions: japanese criteria of obesity in metabolic syndrome in man may be appropriate for diabetes mellitus. |
| PubMedID- 25861160 | In animal models, oa-no2 has demonstrated benefits in hypertension [11], vascular neointimal proliferation [12], obesity with the metabolic syndrome [13], and hyperglycemia in diabetes [14]. |
| PubMedID- 25861250 | The oa-no2, a nitrated fatty acid and an endogenous ppars agonist, has been reported to have relevant biological effects on inflammation [11], hypertension [12], vascular neointimal proliferation [13], obesity with metabolic syndrome [7], hyperglycemia [14], and proteinuria [15] in diabetes without side effects. |
| PubMedID- 20015201 | As shown by gonzales-sanchez and coworkers the enpp1 121q allele might contribute to the genetic susceptibility to abdominal obesity among subjects with metabolic syndrome [36]. |
| PubMedID- 23689359 | obesity is often part of the metabolic syndrome, a condition which includes insulin resistance, dyslipidemian, reduced hdl cholesterol, and hypertension. |
| PubMedID- 26291691 | obesity is strongly associated with metabolic syndrome. |
| PubMedID- 26504474 | These results suggest that bc ameliorated dyslipidemia, hypertension, insulin resistance, and obesity in rats with hf-induced metabolic syndrome. |
| PubMedID- 26473366 | Both insulin resistance and central obesity predict the development of metabolic syndrome, which increases the risks of type 2 diabetes, hyperlipidemia, and cardiovascular disease [6–8]. |
| PubMedID- 20883237 | In the population with abdominal obesity and components of the metabolic syndrome, telmisartan did not increase insulin sensitivity. |
| PubMedID- 23277742 | Blood pressure was not measured, which limits the associations of obesity with the metabolic syndrome as a cluster of potential risk factors for atherosclerotic cardiovascular disease and type 2 diabetes. |
| PubMedID- 21383912 | Both factors are associated with obesity and a range of metabolic syndromes (figure 3). |
| PubMedID- 20938439 | Background: excessive energy intake and obesity lead to the metabolic syndrome (mets). |
| PubMedID- 25603918 | These include obesity, a component of the ‘metabolic syndrome’,7 and reduced bone mineralisation that can result in frank osteoporosis8; both disorders contribute to diminished physical activity and carrying the burden of morbidity and mortality. |
| PubMedID- 25713801 | Non-alcoholic fatty liver disease (nafld) represents the most common liver disorder in western countries and it is commonly associated with obesity and progression of the metabolic syndrome. |
| PubMedID- 22277936 | Insulin resistance and obesity are components of the metabolic syndrome that includes development of cardiovascular disease and diabetes with advancing age. |
| PubMedID- 21674931 | It was found that bariatric intervention fulfilled in earlier age groups would prevent the development of metabolic syndrome (ms) in patients with obesity at later date. |
| PubMedID- 26170848 | Another current hypothesis proposes that obesity is associated with metabolic syndrome, which activates mitogenic molecular processes in breast epithelial cells and stimulates neoplasia. |
| PubMedID- 25885657 | Participants satisfying the full criteria will be classified as having metabolic syndrome; whereas those with central obesity (waist circumference >94 cm men or >80 cm women [europids, sub-saharan africans, eastern mediterranean, middle east]; >90 cm men or >80 cm women [south asians, chinese, japanese]) plus any one of: raised triglyceride level (>1.7 mm, or treatment for this); reduced hdl-cholesterol (<1.03 mm in males and <1.29 mm in females, or treatment for this); will be classified as being at risk of metabolic syndrome. |
| PubMedID- 20129610 | The risk of obesity-induced metabolic syndrome is higher in asians than in caucasians. |
| PubMedID- 25714610 | With more than 1.4 billion overweight or obese adults worldwide, obesity and progression of the metabolic syndrome are major health and economic challenges. |
| PubMedID- 23762545 | Besides improving osa, weight reduction seems to improve also other obesity-related disturbances of cardiometabolic syndrome [20, 39]. |
| PubMedID- 26323878 | Nafld is the most common chronic liver disease in children and adults, with its prevalence closely associated with obesity and other features of the metabolic syndrome. |
| PubMedID- 23641354 | obesity is strongly associated with metabolic syndrome (mets) and comorbidities such as insulin resistance, type 2 diabetes mellitus (t2dm), cardiovascular disease, and cancer, as well as increased risks for all-cause mortality [2-4]. |
| PubMedID- 24587762 | Suggested that visceral obesity, a component of the metabolic syndrome, adversely affects endothelial function and testosterone levels, leading to hypogonadism and erectile dysfunction [23]. |
| PubMedID- 21884160 | This paper reviews epidemiological evidence demonstrating the association between chronic social stress and development of obesity and symptoms leading to metabolic syndrome. |
| PubMedID- 25916862 | Renin-angiotensin-aldosterone system (raas) inhibition with an ace or an arb and treatment with calcium channel blockers appears safe and well tolerated in obesity-related hypertension and in patients with metabolic syndrome. |
| PubMedID- 21688564 | Nafld as the hepatic manifestation of the metabolic syndrome (ms) is associated with obesity, diabetes mellitus and dislipidemia. |
| PubMedID- 25683064 | Central obesity as a component of metabolic syndrome likely correlates with socioeconomic factors. |
| PubMedID- 23359358 | It has also been suggested that surgical treatment could be more effective than conventional treatment for resolving the metabolic syndrome in individuals with mild obesity (bmi = 30–35 kg/m2) (34). |
| PubMedID- 21552555 | Genetic variants in several genes are known to influence bmi, but these mutations are rare and often cause severe monogenic syndromes with obesity [4]. |
| PubMedID- 23476785 | The incidences of breast cancer as well as of the metabolic syndrome with obesity, insulin resistance, hyper-insulinemia, high blood pressure, and type 2 diabetes have increased over the past decades in industrialized countries. |
| PubMedID- 21197447 | Both cachexia and obesity with/without the metabolic syndrome (mets) represent two poles of metabolic abnormalities that are prevalent in patients with copd and are related to adverse clinical outcomes [1]. |
| PubMedID- 23349936 | These studies may serve to identify how serum markers are associated with demographic variables (such as age, sex or ethnicity), lifestyle factors (such as alcohol consumption and smoking), and common metabolic abnormalities (such as obesity and components of metabolic syndrome). |
| PubMedID- 20236509 | This finding is consistent with the observation that in children, obesity is strongly associated with metabolic syndrome [10,11]. |
| PubMedID- 21765599 | (23,24) if xylitol stimulates lipogenesis, it might induce steatosis and obesity, leading to metabolic syndrome. |
| PubMedID- 26005080 | obesity is strongly associated with the metabolic syndrome and its atherogenic dyslipidemia resulting from insulin resistance. |
| PubMedID- 23208524 | Nafld may represent the hepatic manifestation of the metabolic syndrome with visceral obesity, dyslipidaemia, and insulin resistance [198]. |
| PubMedID- 22858531 | Because obesity is a component of the metabolic syndrome, our results seem inconsistent, with several studies suggesting that this syndrome is a risk factor for cognitive decline and dementia. |
| PubMedID- 24647445 | It is well established that central obesity is the hallmark of the metabolic syndrome [3]. |
| PubMedID- 25430602 | Pcos is underpinned by insulin resistance and is associated with comorbidities including hypertension, dyslipidemia, obesity, and increased risk of metabolic syndrome and type 2 diabetes mellitus [12–15]. |
| PubMedID- 25055476 | Bmi does not allow to distinguish lean body mass from fat mass and therefore to evaluate abdominal obesity which is associated with metabolic syndrome and cv risk. |
| PubMedID- 20576133 | Childhood obesity heightens childhood risk of metabolic syndrome, indicating that prevention of early onset obesity may substantially reduce the prevalence of metabolic syndrome in youth and their future risk of life-threatening conditions such as diabetes and cardiovascular disease [4]. |
| PubMedID- 26400710 | Glycyrrhizin, a major constituent of licorice (glycyrrhiza glabra) root, has been reported to ameliorate insulin resistance, hyperglycemia, dyslipidemia, and obesity in rats with metabolic syndrome. |
| PubMedID- 22584415 | Some [39, 40], but not other [41, 42], authors found that plasma resistin levels positively correlate with obesity and other constituents of the metabolic syndrome. |