PedAM
Pediatric Disease Annotations & Medicines
| Disease | migraine with aura |
| Phenotype | |migraine with aura |
| Sentences | 316 |
| PubMedID- PMC3620235 | Diagnoses of primary headache disorders were grouped as follows: migraine 61% (episodic migraine with aura 22 %, episodic migraine without aura 37%, chronic migraine 2%), episodic (12%) and chronic tension-type headache (8%), trigeminal autonomic cephalalgias (4%), other primary headaches (1%), secondary headaches (13%),cranial neuralgias and facial pain (2%) and currently unclassified (15%). |
| PubMedID- 20205867 | About one-third of the patients had migraine with aura, and about three-fourths reported experiencing other kinds of headaches or one or more other significant conditions (e.g., anxiety, depression, problems with sleep or focus). |
| PubMedID- 21448379 | Migraine, particularly migraine with aura, is associated with an increased risk for stroke, and coronary artery disease.12 the endothelial cells have multiple functions, which when changed may provide a common pathophysiology for migraine and vascular disease. |
| PubMedID- 24324584 | Of the conditions in which cocs were contraindicated in an estimated 18% women of reproductive age in areas along the u.s.-mexico border, hypertension (8%) was the most common condition, followed by smoking at age 35 or older (5%), and migraine with aura (4%) [17]. |
| PubMedID- 21360158 | However, the concept of migralepsy as a migraine-epilepsy sequence has been the subject of criticism by several authors since most of the reported cases of “migralepsy” do not allow a meaningful and unequivocal migraine-epilepsy sequence and they were genuine occipital seizures imitating migraine with aura [2, 3]. |
| PubMedID- 20369271 | A second case of unresolved, undiagnosed headache involved a 60-year-old woman who had suffered from episodic migraine with aura since puberty and a more-recent 2-year history of left episodic orbitofrontal headache (c. sánchez bueno, portimão). |
| PubMedID- 21642945 | Fhm type 1 is an autosomal dominant type of migraine with aura and hemiparesis, which is linked to the vgcc α1-subunit gene, cacnl1a4 encoding cav2.129, 30, 31. all five fhm1 mutations change the biophysical properties of cav2.1 channels, leading to both gain and loss of p/q-type channel function32, 33. specifically, single channel recording showed that the mutations enhanced the open probability of the cav2.1 channels and shifted the activation gating of the channel to more negative voltages, allowing increased ca2+ influx at more negative membrane potentials in cerebellar neurons33, 34. common treatments with ca2+ channel blockers, such as verapamil, is effective in some fhm1 patients, carrying the cacna1a mutations due to decreased open probability of p/q-type cav2.1 channels and reduced ca2+ influx35. |
| PubMedID- 23024567 | When you suspect migraine with aura, you have to ask additional questions about the aura – the type of aura, the duration, the sequence. |
| PubMedID- 26561052 | The g2087a (rs2927518) polymorphism of inos has been implicated in a variety of diseases, including inflammatory bowel disease, gastric cancer, migraine with aura, septic shock, and non-hodgkin lymphoma [27–30]. |
| PubMedID- 23565708 | The migraine with aura attacks had always been infrequent, occurring less than monthly but she would often experience such headaches some time after a sporting activity, such as netball, consistent with exercise-triggered migraine. |
| PubMedID- 22379397 | Familial hemiplegic migraine type 1 is a form of migraine with aura and reversible hemiparesis also caused by missense nucleotide mutations in the cacna1a gene that alter channel gating and enhance the channel activity at negative potentials [21]. |
| PubMedID- 22807908 | Sporadic hemiplegic migraine (shm) is a rare subtype of migraine with aura (ma). |
| PubMedID- 26245188 | Only in one of these patients did the attacks disclose the features of migraine with aura but did not present a strict temporal relationship (within one hour) with seizure onset. |
| PubMedID- 20969805 | Genetic research in the field of migraines has mainly focused on the identification of genes involved in familial hemiplegic migraine (fhm), a rare monogenic subtype of migraine with aura. |
| PubMedID- 25750539 | Oral anticoagulants for an inr of 2–3 are recommended for patients who meet the criteria for antiphospholipid syndrome.65 migraine with aura is associated with a six to eight-fold increased risk of stroke in patients under the age of 45 years, but future stroke occurrence remains unclear. |
| PubMedID- 20396640 | Cm, moreover, should be considered as distinct from migraine with aura (ma), migraine without aura (mwoa), and migraine aura without headache (without a history of characteristic migraine headaches). |
| PubMedID- 25916332 | Signed informed consent was obtained from all patients before participation in the study.table 2demographical characteristics of migraine cases and controlsparametercases (n = 291)controls (n = 314)age: mean (range)46.4 (−18-67)44.4 (18–63)sexmale7089female221225ma227n/amo64n/ama - migraine with aura, mo - migraine without aura, n/a - not applicable. |
| PubMedID- 23574797 | migraine with aura was not increased although all patients were interviewed in detail about aura symptoms. |
| PubMedID- 21110235 | The effect was strongest for migraine with aura only, but it was also seen in the all-migraine group. |
| PubMedID- 22536065 | According to the nomenclature, this was a case of chronic daily headache, namely nocturnal migraine with aura, which lasted more than 3 months and occurred at least 15 days per month. |
| PubMedID- 24116342 | 5) had migraine with aura. |
| PubMedID- 21442332 | Furthermore, how do factors such as migraine with aura, gender, race and previously used prophylactic medication influence on the efficacy of onabotulinumtoxina? |
| PubMedID- 20585826 | Table 4 summarizes results from the pooled and meta-analyses based on an allele model and table 5 a pooled analysis based on a genotype model.table 3odds ratios (95% confidence intervals) and hardy–weinberg equilibrium for the association between the slc6a4 stin2 vntr polymorphism and migraineauthordisease statusstudy sizeallele modelagenotype modelbor (95% ci)p valuehwestin2.10/stin2.12stin2.10/stin2.10othercor (95% ci)p valueor (95% ci)p valueor (95% ci)p valueogilvie [10]controls133referent0.48referentreferentreferentany migraine2850.77 (0.57–1.04)0.09–0.52 (0.33–0.82)0.0050.67 (0.35–1.29)0.231.57 (0.43–5.72)0.50ma940.88 (0.60–1.29)0.51–0.49 (0.27–0.90)0.020.83 (0.37–1.84)0.642.10 (0.50–8.95)0.32mo1730.74 (0.54–1.03)0.08–0.56 (0.34–0.92)0.020.65 (0.32–1.33)0.231.12 (0.27–4.70)0.88lea [13]controls141referent0.0001referentreferentreferentany migraine1480.99 (0.71–1.38)0.95–0.96 (0.56–1.65)0.870.97 (0.53–1.75)0.911.17 (0.30–4.57)0.82ma811.01 (0.68–1.49)0.96–0.96 (0.51–1.84)0.911.00 (0.50–2.02)1.001.30 (0.28–6.16)0.74mo670.97 (0.64–1.47)0.87–0.95 (0.48–1.88)0.880.93 (0.44–1.97)0.841.02 (0.18–5.88)0.98yilmaz [9]controls79referent0.01referentreferentreferentany migraine372.09 (1.19–3.67)0.01–3.20 (1.25–8.22)0.023.18 (1.07–9.41)0.04–d–dracchi [11]controls32referent0.28referentreferentreferentma440.66 (0.35–1.27)0.21–1.81 (0.61–5.42)0.290.25 (0.05–1.20)0.08–d–dszilagyi [12]controls464referent0.42referentreferentreferentany migraine870.81 (0.58–1.15)0.24–0.78 (0.48–1.28)0.330.61 (0.27–1.39)0.241.05 (0.28–3.85)0.95ma380.62 (0.37–1.05)0.07–0.51 (0.25–1.05)0.070.44 (0.13–1.53)0.191.32 (0.28–6.29)0.72mo490.99 (0.64–1.52)0.96–1.09 (0.57–2.06)0.800.81 (0.29–2.28)0.690.74 (0.09–5.95)0.77hwep value for hardy–weinberg equilibrium, ma migraine with aura, mo migraine without auraacompares stin2.9 and stin2.10 versus stin2.12 allelesbcompares each of the genotypes versus the stin2.12/stin2.12 genotypecstin2.9/stin2.10 and stin2.9/stin2.12din some groups there were no other genotypestable 4allele model: pooled and meta-analyses of the association between the slc6a4 stin2 vntr polymorphism and migrainemigraine categorystudy populationsno. |
| PubMedID- 23409185 | Such compounds may show potential in diuretic-refractory edematous conditions like severe congestive heart failure, cancer and migraine with aura. |
| PubMedID- 23372843 | Furthermore, a cohort study using data from women's health study showed that migraine with aura was a risk factor of hs (adjusted hr 2.25, 95% ci, 1.11 – 4.54) [8]. |
| PubMedID- 24466320 | Recently, a frameshift mutation in human kcnk18 gene encoding the tresk channel subunits has been linked to migraine with aura in a large pedigree [3]. |
| PubMedID- 19946790 | migraine with aura restrictive migraine criteria, and visualb disturbance prior to or during headacheiii. |
| PubMedID- 23577145 | Familial hemiplegic migraine type 1 (fhm-1) is a rare monogenic subtype of migraine with aura that is caused by missense mutations in the cacna1a gene [1] that encodes the α1 subunit of neuronal voltage-gated cav2.1(voltage-gated calcium channel type 2.1) calcium channels [2]. |
| PubMedID- 22584531 | Bdnf serum concentrations are listed in table 2.table 1demographic and clinical data of the study populationcharacteristicsmigraine with auramigraine without auracluster headachetension-type headachehealthy controlsoutside attackduring attackoutside attackduring attackoutside boutinside boutoutside attackheadache freen22132782442622mean age (±sd)32.05 (±10.05)31.48 (±7.89)39.98 (±13.19)30.83 (±5.60)28.63 (±3.88)female gender, n (%)17 (77)20 (74)7 [13]5 (83)10 (45)paired, n11814n.a.n.a.n.a. |
| PubMedID- 21822390 | Additional neurological manifestations include migraine with aura and stroke.63 in most clinical studies of cadasil, patients are documented to suffer from migraine or recurrent headaches; different studies report occurrence of migraine in 22%–64% of patients.15 migraine is usually the first symptom, with the mean age of onset in the late twenties.25,64–68 cadasil migraine is typically associated with aura. |
| PubMedID- 26334887 | Migraine is a common and disabling type of primary headache disorder comprising 2 major subgroups: migraine with aura (ma) and migraine without aura (mo).1 heredity, polluted environment, and hormonal factors individually or jointly confer susceptibility to this genetically complex disease. |
| PubMedID- 23720232 | Clinical symptoms comprise migraine with aura, leukoaraiosis, subcortical infarcts, mood disturbances, apathy and dementia (hervé and chabriat, 2010). |
| PubMedID- 19949829 | Publications on headache in arabs were identified by searching the keywords “headache” or “vascular headache” or “tension-type headache” or “headache disorders, primary” or “cluster headache” or “post-dural puncture headache” or “headache disorders” or “post-traumatic headache” or “headache disorders, secondary” or “migraine disorders” or “migraine with aura” combined with “arabs”, “arab countries”, “north africa”, “middle east”, “gulf” and “specific country names” in medline (1950 date). |
| PubMedID- 24456509 | In about 30% of patients migraine attacks are preceded by transient focal neurologic symptoms which are called aura (migraine with aura, ma). |
| PubMedID- PMC3619996 | Since aura and chcs are independent risk factors for ischaemic stroke, the appropriateness of chcs solely for contraception in women who have migraine with aura needs careful consideration. |
| PubMedID- 25789137 | Migraine especially migraine with aura (ma), is associated with an increased risk for several vascular disorders, such as ischemic stroke, myocardial infarction, and death due to ischemia, as well as with coronary revascularization and angina. |
| PubMedID- 22396786 | The 14 patients in the control group had the following diagnoses: migraine with aura, episodic headache and symptomatic epilepsy, transient ischemic attack, borreliosis, anterior ischemic optic neuropathy (aion), pd, vestibular neuritis with depression and iron deficiency anemia, pseudotumor cerebri (ptc), migraine and polymyalgia rheumatica. |
| PubMedID- 25205974 | Basilar-type migraine – this is an uncommon type of migraine with aura wherein the symptoms are referable to brainstem and comprise bilateral blurred vision, vertigo, ataxia, incordination and nausea. |
| PubMedID- 26272681 | We did not attempt to separately diagnose migraine with aura and migraine without aura. |
| PubMedID- 22065121 | In acm, the symptoms of prolonged migraine with aura, impaired language functions and decreased responsiveness, or confusion and agitation are common [3]. |
| PubMedID- 21890526 | 447.0 ± 10.844.4 ± 9.244.3 ± 10.644.4 ± 11.3sex male2 (7)5 (17)2 (6)9 (10)6 (8) female28 (93)25 (83)29 (94)82 (90)66 (92)weight (kg)69.8 ± 9.870.1 ± 13.375.6 ± 15.072.1 ± 13.072.1 ± 12.7height (cm)170 ± 6.5170 ± 8.4170 ± 6.4170 ± 7.1170 ± 6.4body mass index (kg/m2)24.1 ± 2.324.9 ± 4.126.4 ± 4.825.1 ± 3.925.1 ± 3.9smoking1 (3)2 (7)3 (10)6 (7)5 (7)type of migraine migraine with aura1 (3)3 (10)3 (10)7 (8)5 (7) migraine without aura16 (53)11 (37)17 (35)44 (48)34 (47) migraine with and without aura13 (43)16 (53)11 (55)40 (44)33 (46)duration of disease (years)22.2 ± 11.828.8 ± 11.025.1 ± 11.425.4 ± 11.625.7 ± 11.9baseline frequency of migraine (days)7.6 ± 3.87.0 ± 3.87.5 ± 3.97.3 ± 3.87.2 ± 3.6baseline frequency of migraine attacks (numbers of attacks)4.2 ± 1.64.3 ± 2.03.6 ± 1.64.0 ± 1.84.1 ± 1.7baseline frequency of headache medication used (doses)6.5 ± 4.66.9 ± 4.17.1 ± 5.36.8 ± 4.67.4 ± 4.8baseline intensity of pain (vas)39 (26–55)50 (26–64)40 (29–58)40 (29–61)45 (30–63)baseline msqol58 (51–67)60 (43–77)60 (48–73)60 (47–72)59 (50–71)baseline oxygen uptake (ml x kg−1 x min−1)34.9 ± 2.433.8 ± 1.730.9 ± 2.133.2 ± 1.232.7 ± 1.1data are expressed as number (%), mean±standard deviation or median (interquartile range). |
| PubMedID- 20862508 | migraine with aura (ma) is a well known and thoroughly studied disease [1]. |
| PubMedID- 24471006 | These visual phenomena in occipital seizures may simulate migraine with aura. |
| PubMedID- PMC3620252 | Six had a history of migraine with aura attacks and 19 meet overuse criteria. |
| PubMedID- 22670162 | In contradiction, csd is thought to be involved in the mechanism of the neurological symptoms in migraine with aura [4, 11] and it has also been reported that csd may occur spontaneously under hypoxic or ischemic conditions [5, 11-13], following traumatic brain injury [2, 14, 15] and was also found to appear after epileptic seizures [11, 16]. |
| PubMedID- 25695049 | Migraine headache was diagnosed using the international headache society (ihs) criteria for migraine with aura (ihs 1.1), migraine without aura (ihs 1.2), and probable migraine (ihs 1.6) [3]. |
| PubMedID- PMC3620247 | Only 3 patients (4.2%) were diagnosed of migraine with aura, one of them appearing after 50 years. |
| PubMedID- 22278639 | Only seven patients had migraine with aura. |
| PubMedID- 25758678 | The level of ppars has no significant differences between migraine with aura group and without aura group, regardless of whether headache attack. |
| PubMedID- 21878097 | The history revealed that the patient was suffering from migraine with aura and therefore she took cafergot® (ergotamine) for 5-6 years, 2-4 mg/day. |