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PedAM

Pediatric Disease Annotations & Medicines




Disease migraine with aura
Phenotype |migraine
Sentences 285
PubMedID- 22278639 Only seven patients had migraine with aura.
PubMedID- 25729594 The primary objective of this study was to evaluate the efficacy and tolerability of acetylsalicylic acid for migraine with aura prophylaxis compared with other prophylactic therapies normally used for migraine in a real world clinical setting.
PubMedID- 25582043 Among nursing staff, the 1-year prevalence of primary headache disorders was 45.3%, of migraine 14.8% (migraine with aura 3.4%, migraine without aura 11.4%), of tension-type headache (tth) 26.2%, of chronic daily headache (cdh) 2.7%.
PubMedID- 23848401 This association seems significant mainly in patients affected by migraine with aura (ma) while in patients affected by migraine without aura (mo) the results are conflicting.
PubMedID- 22302157 The clinical picture may be heterogeneous, but usually the first manifestation of the disease is migraine with aura that occurs in 30% of patients, with a higher prevalence than in general population, followed by recurrent ischemic strokes, psychiatric disturbances and cognitive decline [3–5].
PubMedID- 21157074 His past medical history included classic migraine with aura diagnosed at the age of six years.
PubMedID- 23565708 The migraine with aura attacks had always been infrequent, occurring less than monthly but she would often experience such headaches some time after a sporting activity, such as netball, consistent with exercise-triggered migraine.
PubMedID- 26272681 We did not attempt to separately diagnose migraine with aura and migraine without aura.
PubMedID- 24456509 However, they carry a small, but significant vascular risk, especially in migraine with aura (ma) and, eventually in migraine without aura (mo) with additional risk factors for stroke (smoking, hypertension, diabetes, hyperlipidemia and thrombophilia, age over 35 years).
PubMedID- PMC3620149 It is supposed that handl syndrome could have viral, autoimmune or vascular origin or to be a rare variant of migraine with aura.
PubMedID- 20802479 We jointly analyzed patient samples from three migraine with aura collections from finland, germany and the netherlands with population-matched controls obtained from pre-existing studies.
PubMedID- 21197470 Moreover, the meta-analysis found an increased risk of ischemic stroke among people who had migraine with aura (ma) (rr 2.16, 95% ci, 1.53 to 3.03) but not among those who had migraine without aura (mo) (rr 1.23, 95% ci 0.90 to 1.69), challenging whether mo should be considered a stroke risk factor.
PubMedID- 26448911 Secondly, because subtype of migraine (migraine with aura, etc) is difficult to distinguish, and number of migraine attacks is difficult to capture retrospectively outside of specialty headache clinic, we focused only on collecting information about diagnosis of migraine.
PubMedID- 26141381 Only 10 of the 738 patients who had migraine with aura developed bppv, and no significant difference in irr was found between the migraine patients and controls (irr = 2.48, 95 % ci 0.71–10.81, p = 0.123) (table 2).
PubMedID- 23718283 migraine with aura (ma) involve in addition, but also rarely exclusively, neurologic symptoms (aura) that are caused by waves of cortical spreading depression [12,15-17].
PubMedID- 25793707 Particularly, a failure of inhibitory circuits in migraine with aura been suggested.
PubMedID- 23024567 A useful question to ask in order not to miss migraine with aura would be, “do you have a visual defect or any other neurological problem before or along with the headache?
PubMedID- 21642945 Fhm type 1 is an autosomal dominant type of migraine with aura and hemiparesis, which is linked to the vgcc α1-subunit gene, cacnl1a4 encoding cav2.129, 30, 31. all five fhm1 mutations change the biophysical properties of cav2.1 channels, leading to both gain and loss of p/q-type channel function32, 33. specifically, single channel recording showed that the mutations enhanced the open probability of the cav2.1 channels and shifted the activation gating of the channel to more negative voltages, allowing increased ca2+ influx at more negative membrane potentials in cerebellar neurons33, 34. common treatments with ca2+ channel blockers, such as verapamil, is effective in some fhm1 patients, carrying the cacna1a mutations due to decreased open probability of p/q-type cav2.1 channels and reduced ca2+ influx35.
PubMedID- 25767720 Studies have detected an increased risk for ischemic stroke in patients who had migraine with aura [15–18].
PubMedID- 24461875 The importance of k2p in pain is highlighted by the discovery of a human k+ channelopathy; thus, familial migraine with aura is associated with a dominant-negative mutation in tresk, a subunit strongly expressed in human trigeminal and dorsal root ganglia [67].
PubMedID- 25916332 Classification criteria recognize two types of migraine, migraine with aura (ma) and migraine without aura (mo) with the former accompanied by visual or auditory disturbances [1].
PubMedID- 26266080 This episode of migraine with aura in a patient with recurrent migraine was complicated by side effects of medical diagnostic and therapeutic procedures (extrapyramidal symptoms, delirium, post-lumbar puncture headache, hospital admission) all of which could have been prevented—quaternary prevention.
PubMedID- 24400971 In the case of a migraine with aura, it is recommended that a nsaid is taken immediately at the start of aura to prevent or limit the subsequent headache (professional agreement) and to wait until the start of the headache before taking a triptan (professional agreement).
PubMedID- 23879550 Mechanisms and structures involved in the pathogenesis of migraine with aura.
PubMedID- 23024559 An unexplained but epidemiologically well-established predisposition relates to methyltetrahydrofolate reductase gene mutation c677t that is certainly overrepresented in migraine with aura.
PubMedID- 23450798 Indeed, the other four components of his family, that in this case we can consider as controls, kept suffering from migraine with aura attacks, and all of them are poor responsive to pharmacological therapy.
PubMedID- 26305465 The main clinical symptoms of cadasil are migraine with aura, lacunar strokes, progressive cognitive deficits and depression [3].
PubMedID- 20535330 Her younger sister suffered from migraine with aura (fig.
PubMedID- 26334887 The same genetic models showed notable associations in subgroups of caucasians and migraine with aura (ma).
PubMedID- 21689831 Their neurological examination is normal and their clinical history is poor (the mother suffers from migraine with aura and the father has mildly elevated blood pressure and benign prostatic hypertrophy).
PubMedID- 21110235 The effect was strongest for migraine with aura only, but it was also seen in the all-migraine group.
PubMedID- 20948794 Ma, migraine with aura.
PubMedID- 20855363 Whether cgrp triggers migraine in patients with typical (non-hemiplegic) migraine with aura is (ma) unknown.
PubMedID- 22355750 It is characterized by attacks of severe, usually unilateral and throbbing headache, can be accompanied by nausea, vomiting and photophobia and is clinically divided into two main subtypes, migraine with aura (ma) when a migraine is accompanied by transient and reversible focal neurological symptoms and migraine without aura (mo)1. the multifactorial and clinical heterogeneity of the disorder have considerably hindered the identification of common migraine susceptibility genes and most of our current understanding comes from the studies of familial hemiplegic migraine (fhm), a rare monogenic autosomal dominant form of ma2.
PubMedID- 21490733 He had prior history of migraine with aura (ma) and without aura (mo) from 30 years of age.
PubMedID- 23459313 The migraine with aura group also reported the presence of photopsia, fortification spectra or scotoma with the headache.
PubMedID- PMC3619996 Since aura and chcs are independent risk factors for ischaemic stroke, the appropriateness of chcs solely for contraception in women who have migraine with aura needs careful consideration.
PubMedID- 22577422 All of these cases had migraine with aura.
PubMedID- PMC3620007 Methodology: research has been conducted on a sample of patients suffering from migraine with aura (ma) and those suffering from migraine without aura (m).
PubMedID- 21584641 To complicate matters, what about migraine with aura (ma)?
PubMedID- 24403849 2009 investigated a total of 53 snps in 10 genes from the dopaminergic system, including comt, dbh, ddc, drd1, drd2, drd3, drd4, drd5 slc6a3 and th, in a large german case-control cohort of migraine with aura and from this study the dopamine transporter slc6a3 5p15 and dbh 9q34 enzyme emerged as significant [97].
PubMedID- 26283923 Such lipid messengers (endovanilloids) are probably released in migraine with aura during cortical spreading depression (csd) or in migraine without aura after stress induced mast cell degranulation in meninges (levy, 2010).
PubMedID- PMC3620302 (ii) the visual symptoms are distinct from migraine with aura.
PubMedID- 20862508 migraine with aura (ma) is a well known and thoroughly studied disease [1].
PubMedID- 25595197 Additionally, the association between migraine with aura and ischemic stroke is more apparent for individuals without vascular risk factors [8–10].
PubMedID- 22400994 Patients in the mimics group were suffering from migraine with aura (n = 4), other types of headache (n = 3), seizures with concomitant postictual paresis (n = 12), dizziness (n = 7), syncopes (n = 8), hypertensive encephalopathy (n = 1), idiopathic paresis of the facial nerve (n = 1), transient global amnesia (n = 2) and other diagnosis (n = 11).
PubMedID- 23691227 In addition, a tresk [g339r] functional knockout mice shows an enhanced drg excitability [7] and a dominant-negative mutation in the human channel is linked to familial migraine with aura [11].
PubMedID- 26449228 In our previous study, the 1-year prevalence of primary headache disorders among nursing staff in mainland china was 45.3 %, of migraine 14.8 % (migraine with aura 3.4 %, migraine without aura 11.4 %), of tension-type headache (tth) 26.2 %, and of chronic daily headache (cdh) 2.7 %, remarkably higher than in the general population.
PubMedID- 20058047 Forty-one patients (25.3%) presented migraine with aura.
PubMedID- 20112041 In migraine with aura, epilepsy preceded migraine in 71% of cases.

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