PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Phenotype | |cirrhosis |
| Sentences | 175 |
| PubMedID- 23162602 | Their research has shown high prevalence of viral infection in a1atd-associated chronic liver disease leading to cirrhosis and furthermore to the development of hcc. |
| PubMedID- 26488159 | History of decompensated cirrhosis or other causes of liver disease identified in hiv-infected patients, such as nash or drug-induced liver injury, was not collected as well as other comorbidities, including renal failure. |
| PubMedID- 21829583 | cirrhosis represents the end-stage of any chronic liver disease, characterized by the most advanced stage of fibrosis, distortion of the liver parenchyma associated with septae and nodule formation, altered blood flow and the potential development of liver failure at long term. |
| PubMedID- 26045708 | Alcoholic liver disease can lead to cirrhosis and there is underlying cirrhosis in many ah cases (2, 9). |
| PubMedID- 25553238 | Approximately 20% of those chronically infected will ultimately progress to develop cirrhosis and death due to end-stage liver disease or hepatocellular carcinoma (hcc). |
| PubMedID- 22848841 | The hepatitis c virus (hcv) is one of the most prevalent causes of chronic liver disease worldwide and leads to cirrhosis and hepatocellular carcinoma in a high percentage of carriers [1, 2].insulin resistance (ir), impaired glucose tolerance, and type 2 diabetes mellitus (dm) are frequent extrahepatic manifestations [3, 4]. |
| PubMedID- 25191050 | Chronic liver disease with cirrhosis and hepato-cellular carcinoma is the other spectrum of the disease. |
| PubMedID- 22139986 | Common indications for olt include cirrhosis due to alcoholic liver disease or chronic viral hepatitis related to hepatitis b or c, and hepatocellular carcinoma. |
| PubMedID- 23805158 | Concurrently, persistent chronic hcv infection more potent to developed cirrhosis, end stage of liver disease, and hepatocellular carcinoma is a result of hepatocellular necrosis among other hepatitis virus types (4, 10). |
| PubMedID- 26279293 | Chronic hepatitis c is one of the most important causes of liver disease, leading to cirrhosis, hepatic decompensation and hepatocellular carcinoma. |
| PubMedID- 21994867 | Since the vast majority of hccs occur on a background of liver disease with or without cirrhosis, it is clear that prognosis does not depend exclusively on tumour-related factors but also on liver function, general health, and other comorbidities of the patient and response to various medical treatments depending on the aetiology [5]. |
| PubMedID- 24455970 | This study included 313 normoalbuminuric type 1 diabetic patients with estimated glomerular filtration rate (egfr) >60 ml/min/1.73 m(2), without clinical evidence of cirrhosis or other causes of chronic liver disease and before any interventions with statins, angiotensin-converting enzyme (ace) inhibitors or angiotensin ii receptor blockers. |
| PubMedID- 22359269 | The present study aimed to investigate the biological actions of tricin on hepatic stellate cells (hscs) in vitro, exploring its potential as a treatment of liver fibrosis, since hsc proliferation is closely related to the progression of hepatic fibrogenesis in chronic liver diseases leading to irreversible liver cirrhosis and hepatocellular carcinoma. |
| PubMedID- 23091807 | Patients with liver cirrhosis and other forms of liver disease or other severe underlying diseases, i.e. |
| PubMedID- 25276280 | Infection by the hcv can cause acute and chronic liver diseases and may lead to cirrhosis, hepatocellular carcinoma or liver failure. |
| PubMedID- 22576780 | Background: non-alcoholic fatty liver disease (nafld) can lead to cirrhosis and hepatocellular carcinoma and is strongly associated with obesity and insulin resistance. |
| PubMedID- 25337145 | Background: a single nucleotide polymorphism (snp) of patatin-like phospholipase domain-containing 3 (pnpla3) genes (rs738409) is associated with the severity of fibrosis and cirrhosis in patients with fatty liver disease. |
| PubMedID- 23543867 | Additional subgroup analysis to estimate the influence of various factors like percentage of patients with alcoholic liver disease (ald) as cause of cirrhosis, dose of terlipressin used (>4mg/d and<4mg/d); type of interventions used (terlipressin with vs without albumin; terlipressin vs placebo; terlipressin vs noradrenaline), blinding and quality score of study (studies of low quality vs high quality) was also conducted. |
| PubMedID- 21713221 | cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules leading to loss of liver function. |
| PubMedID- 23886860 | Mice fed a diet containing 40% fat (of which approximately 18% was trans fat), 22% fructose, and 2% cholesterol developed three stages of nonalcoholic fatty liver disease (steatosis, steatohepatitis with fibrosis, and cirrhosis) as assessed by histological and biochemical methods. |
| PubMedID- 22916250 | cirrhosis represents the end-stage of any chronic liver disease, characterized by the most advanced stage of fibrosis, distortion of the liver parenchyma associated with septae and nodule formation, altered blood flow and the potential development of liver failure at long term. |
| PubMedID- 23831905 | Autoimmune hepatitis (aih) is a chronic inflammatory liver disease leading to cirrhosis and its complications if left untreated. |
| PubMedID- 26058465 | Persistent hbv infection can promote liver disease, thereby leading to hepatitis and cirrhosis [29]. |
| PubMedID- 24625898 | Purpose of review: primary biliary cirrhosis (pbc) can lead to end-stage liver disease and death. |
| PubMedID- 26447841 | [1, 2] more than 80% of hcc arise in a background of chronic liver disease with liver cirrhosis caused by chronic hepatitis b or c virus infection, alcohol abuse or obesity with non-alcoholic fatty liver disease. |