PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Phenotype | |hepatitis |
| Sentences | 144 |
| PubMedID- 25896946 | Decompensated liver disease resulting from hepatitis c virus (hcv) infection is a leading indication for liver transplantation [1]. |
| PubMedID- 21145859 | Role of a cirrhosis risk score for the early prediction of fibrosis progression in hepatitis c patients with minimal liver disease. |
| PubMedID- 23869664 | Progression of liver disease is common with hepatitis c virus (hcv) infection and known to be accelerated in the presence of hiv 4,5. according to current guidelines, all coinfected patients with chronic hcv infection and significant fibrosis (≥f2) should be considered for hcv therapy given their increased risk of death from liver disease 6,7. hcv treatment should preferentially be offered to patients with controlled hiv infection, and therefore it is recommended when cd4 cell counts are above 350 cells/μl and often deferred when counts are below 200 cells/μl 7. however, patients with cd4 cell counts below 200 cells/μl have been shown to respond well to hcv treatment when hiv replication is suppressed 8. despite these recommendations, the extent to which hiv/hcv-coinfected patients start hcv therapy is not well documented in europe. |
| PubMedID- 24005956 | Key exclusion criteria included: (1) presence of liver cirrhosis or hepatic failure, or other liver disease, (2) infection/co-infection with hiv-1, hiv-2, hepatitis b or nongenotype 1 hcv, (3) malignant tumor within 5 years prior to study, (4) hcc, (5) meeting conditions that required caution with pegifnα-2a or rbv treatment, (6) any clinically significant disease, (7) organ transplant, and (8) defined laboratory abnormalities during screening. |
| PubMedID- 23324345 | Hepatic fibrosis results from many chronic liver diseases, including hepatitis b virus (hbv), hepatitis c virus (hcv), alcoholic liver disease and non-alcoholic steatohepatitis (nash).1 hepatic fibrosis is the scar caused by deregulation of physiological wound healing and results in excessive production of extracellular matrix (ecm), mostly collagen type i. myofibroblasts, which are not present in normal liver, are the major source of the ecm during fibrogenesis. |
| PubMedID- 25320839 | Background: heavy alcohol use has been hypothesized to accelerate disease progression to end-stage liver disease in patients with hepatitis c virus (hcv) infection. |
| PubMedID- 22537436 | Noninvasive methods to assess liver disease in patients with hepatitis b or c. |
| PubMedID- 26441244 | In addition to alcoholic induced hepatitis, the importance of non-alcoholic fatty liver disease (nafld) has progressively been emphasized in recent decades worldwide. |
| PubMedID- 22798114 | Methods: the study enrolled 94 chronic hepatitis b patients with compensated liver disease. |
| PubMedID- 23241078 | The economic burden of advanced liver disease among patients with hepatitis c virus: a large state medicaid perspective. |
| PubMedID- 24723944 | Had underling liver disease with mostly hepatitis c virus (hcv) serologically positive (123/271, 45.4%) but not with hbv (78/271, 28.8%); however, the patients in our study were most hbv serologically positive (312/413, 75.5%). |
| PubMedID- 25288416 | We found nationwide trends in increasing morbidity and medical costs for advanced liver disease associated with hepatitis c. |
| PubMedID- 25848478 | However, chronic hepatitis c is associated with a higher liver disease related cardiovascular and all-cause mortality of hd patients. |
| PubMedID- 22505377 | Background/aims: hepatitis c virus leads to chronic liver disease, cirrhosis and hepatocellular cancer. |
| PubMedID- 23622604 | There is an extremely high burden of liver disease owing to viral hepatitis b (hbv); about 2 billion people are infected and 350 million are chronic carriers of hbv worldwide. |
| PubMedID- 23101979 | Alcoholic hepatitis is a form of severe, cholestatic liver disease that results from consumption of large amount of alcohol during a sustained period of time in a subset of alcoholics. |
| PubMedID- 25732561 | Exclusion criteria were ongoing acute or chronic hepatitis, presence of other diagnosed liver diseases, signs of biliary obstruction, daily alcohol intake >30 mg, concomitant use of antioxidant products such as silymarin, ademethionine and glutathione, uncontrolled diabetes mellitus and/or major change in antidiabetic therapy within the previous 3 months. |
| PubMedID- 20461127 | [18], francetwo double-blind, placebo controlled trials to investigate the safety and tolerability of two dosing regimens of adv (10 mg daily or 30 mg daily), 48-wk follow-up.n = 515 in the 10-mg study and 185 in the 30-mg study, chronic hepatitis b patients with compensated liver disease not undergoing treatment with evidence of viral replication.no overall median change from baseline in serum creatinine or phosphorus levels in 10 mg group. |
| PubMedID- 22012714 | The virologic determinants of progressive liver disease associated with hepatitis b virus (hbv) remain unclear. |
| PubMedID- 21188525 | Dietary history and physical activity and risk of advanced liver disease in veterans with chronic hepatitis c infection. |
| PubMedID- 21254162 | Data are limited on the safety and effectiveness of oral antivirals other than lamivudine and adefovir dipivoxil for treatment of chronic hepatitis b (chb) in patients with decompensated liver disease. |
| PubMedID- 23229244 | liver disease (including hepatitis and cirrhosis) was also detected in a group of croatian olp patients (42/175, 24%), (16). |
| PubMedID- 21809486 | The purpose of this study was to determine the serum level of oxidized low-density lipoprotein (ox-ldl), and evaluate its association with different clinically valuable parameters of liver disease in patients with chronic hepatitis c. |
| PubMedID- 24587152 | Co-infection with viral hepatitis enhances the progression of liver diseases; significantly increasing the risk of morbidity and mortality among people living with hiv [28]. |
| PubMedID- 26294919 | Initial findings revealed that human bm-mscs were able to improve liver function in hepatitis b patients with end-stage liver disease [45]. |
| PubMedID- 25400432 | Chronic liver disease including hepatitis c virus (hcv) infection is one of the main cause for the development of hepatic angiogenesis and thereby plays a critical role in the modulation of hepatic angiogenesis that finally leads to hepatocellular carcinoma progression and invasion. |
| PubMedID- 21057383 | Importance of hepatitis vaccination in patients with chronic liver disease. |
| PubMedID- 23874824 | Among the main causes of liver disease, co-infection with the hepatitis c (hcv) or hepatitis b (hbv) virus is the most frequent and has the worst prognosis [3]. |
| PubMedID- 21294867 | The high proportion of patients with chronic liver disease associated with hepatitis c virus coinfection might have contributed to lessen the differences between treatment groups. |
| PubMedID- 20334631 | Site-specific k18 hyperphosphorylation was shown to strongly correlate with the progression of liver diseases in patients with chronic noncirrhotic hepatitis c virus (hcv) [17]. |
| PubMedID- 25088088 | Background and aim: assessment of the severity of liver disease following infection with hepatitis c virus (hcv) is important in treatment selection and prognosis. |
| PubMedID- 22419479 | We enrolled 184 hepatitis c-infected patients with chronic liver diseases or hcc, 57 healthy subjects and 27 hcc patients with other etiology. |
| PubMedID- 21418886 | After excluding those patients diagnosed with hepatotropic viral hepatitis, space occupying lesions of the liver, alcoholic liver disease and obstruction of bile duct caused by stone or malignancy and ama/ama-m(2) positive of primary biliary cirrhosis (pbc), the clinical and histological characteristics were evaluated. |
| PubMedID- 23630437 | Status of essential trace minerals and oxidative stress in viral hepatitis c patients with nonalcoholic fatty liver disease. |
| PubMedID- 21191876 | [low response rate to a vaccination against hepatitis b in patients with end-stage liver disease]. |
| PubMedID- 26246574 | More than 500,000 people die each year from the liver diseases that result from chronic hepatitis b virus (hbv) infection. |
| PubMedID- 20927314 | In this letter, the company mentioned that there had been some postmarketing reports of cholestatic jaundice and hepatitis in patients with chronic liver disease or cirrhosis receiving duloxetine. |
| PubMedID- 25208465 | liver diseases were mostly attributed to hepatitis b virus infection (32%). |
| PubMedID- 25757571 | Hcv is a major cause of chronic hepatitis worldwide; often leading to chronic liver disease with the potential for development of hepatocellular carcinoma. |
| PubMedID- 23252849 | Specific mutations of basal core promoter are associated with chronic liver disease in hepatitis b virus subgenotype d1 prevalent in turkey. |
| PubMedID- 25801076 | Background: the pnpla3/adiponutrin rs738409 c/g single nucleotide polymorphism is associated with the severity of steatosis, steatohepatitis and fibrosis in patients with non-alcoholic fatty liver disease, as well as the severity of steatosis and fibrosis in patients with chronic hepatitis c (chc). |
| PubMedID- 23226395 | liver diseases resulting from hepatitis c virus (hcv) infection is a major health issue worldwide as well as the united states [1], [2]. |
| PubMedID- 22163170 | The most common indication for lt was end-stage liver disease attributed to hepatitis c infection. |
| PubMedID- 26469342 | Exclusion criteria included evidence of alcoholic liver disease and co-infection with hepatitis b and hepatitis c. age, gender, height, weight, body mass index (bmi), serum aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin and platelet counts were recorded, and apri scores were calculated at the time of histopathological examination. |