PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Phenotype | |cirrhosis |
| Sentences | 175 |
| PubMedID- 20619382 | Background: hepatitis c virus (hcv) causes chronic liver disease that often leads to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 22745742 | Hepatitis c virus (hcv) is a major cause for chronic liver disease leading to liver cirrhosis and hepatocellular carcinoma (hcc) [1]. |
| PubMedID- 24843689 | In a 21‐year follow up of biopsy‐proven nafld, the main causes of death were cardiovascular disease and malignancy12, as opposed to cirrhosis in those with alcoholic liver disease. |
| PubMedID- 24533141 | cirrhosis is a consequence of chronic liver disease characterized by the replacement of liver tissue by fibrosis, scar tissue, and regenerative nodules, which leads to loss of liver function. |
| PubMedID- 22829332 | On the basis of the above-mentioned hypothesis that occult hbv might be unable to produce severe hepatic injury by itself, it appears difficult to provide an explanation to the considerable evidence indicating that obi is associated with the progression of liver fibrosis and cirrhosis development also in patients with cryptogenic liver disease [5, 20]. |
| PubMedID- 21949642 | The latency period for liver cirrhosis, the major category of liver disease mortality, is long, up to 20 y of excessive drinking [28]. |
| PubMedID- 25922602 | We constructed a stepwise logistic regression using age, meld at lt, hepatitis c (hcv) cirrhosis as a cause of the liver disease, and presence of a combined liver-kidney transplant to determine whether the covariates accounted for differences in recipient qol scores. |
| PubMedID- 24974878 | Ir is common in euglycemic cirrhosis and with advancement of liver disease; there is a compensatory increase in pancreatic β-cell insulin secretion to overcome the ir. |
| PubMedID- 23247798 | Background: primary sclerosing cholangitis (psc) is a chronic cholestatic liver disease leading to cirrhosis and cholangiocellular carcinoma. |
| PubMedID- 26386160 | As this cohort ages, progressive hcv-related liver disease leading to cirrhosis and hepatocellular carcinoma (hcc) will place a significant burden on the healthcare system. |
| PubMedID- 21994876 | Lamivudine, the first oral antiviral agent available for hepatitis b treatment is safe and effective and can improve or stabilize liver disease in patients with advanced cirrhosis and viraemia. |
| PubMedID- 23303023 | cirrhosis, end-stage of many liver diseases, presents many complications during its evolution. |
| PubMedID- 24843757 | Patients who had any clinical evidence of cirrhosis or other causes of chronic liver disease were excluded. |
| PubMedID- 22204909 | Hepatitis c virus (hcv) infection is a main cause of chronic liver disease, leading to liver cirrhosis and hepatocellular carcinoma (hcc). |
| PubMedID- 26077449 | Iron-overload-mediated liver disease leads to end-stage cirrhosis and/or hepatocellular carcinoma. |
| PubMedID- 21884247 | Entecavir treatment for 12 months decreased mean model for end-stage liver disease scores in patients with cirrhosis and hcc (7.2 vs 5.6, p < 0.001). |
| PubMedID- 22420979 | Although cirrhosis and other causes of chronic liver disease have been implicated, their contribution as risk factors for cholangiocarcinoma is unclear and our aims were to analyze these emerging potential risk factors by systematic examination of case-control series from geographically diverse regions. |
| PubMedID- 22893871 | Data at enrollment, including age, sex, ctp score, model for end-stage liver disease (meld) score, cause of cirrhosis, presence of esophageal varix, use of antiviral treatment, coexistence of diabetes, coexistence of hypertension, prothrombin time, international normalized ratio, albumin, total bilirubin, creatinine, aspartate aminotransferase, and alanine aminotransferase, were collected. |
| PubMedID- 24714308 | In another study, anti-p were found in 40% of patients with primary biliary cirrhosis, but not in patients with alcoholic liver disease [13]. |
| PubMedID- 24019010 | It can cause chronic liver disease and lead to liver cirrhosis and cancer [1]. |
| PubMedID- 25298585 | [56] this includes age, type of hrs, alcoholic liver disease (ald) as cause of cirrhosis, baseline map level, baseline serum bilirubin level, baseline serum creatinine level, baseline child-pugh score and others. |
| PubMedID- 25922775 | It is estimated that the main causes of liver disease leading to cirrhosis and/or hcc in europe include hepatitis c (hcv) infection in 60% of patients, hepatitis b (hbv) infection in 15% of patients, and alcohol abuse in 10% of patients. |
| PubMedID- 25540037 | The development of chronic hepatitis b virus-mediated liver disease may lead to liver fibrosis, cirrhosis and eventually hepatocellular carcinoma. |
| PubMedID- 26034765 | Hepatic steatosis is the first pathophysiological step for nonalcoholic steatohepatitis (nash), a progressive liver disease leading to cirrhosis and related complications [6]. |
| PubMedID- 23431353 | Hepatic fibrosis is a common pathological process of chronic liver diseases and would lead to cirrhosis, and fuzheng huayu (fzhy) is an effective chinese herbal product against liver fibrosis. |
| PubMedID- 23140577 | Hepatitis c virus (hcv) is a hepacivirus that causes chronic liver disease, leading to hepatocellular carcinoma, cirrhosis, and chronic hepatitis in about 3% of the world population. |
| PubMedID- 22102439 | Although other outcomes related to non-alcoholic fatty liver disease, including cirrhosis, cancer, and a more rapid progression of coexistent liver diseases may be important, our findings support the suggestion that people with accumulation of fat in the liver have a good prognosis with respect to mortality. |
| PubMedID- 23837137 | liver disease, including cirrhosis, is one of the leading causes of morbidity and mortality in korea and ranked the 8th most common cause of death in 2007.1 spontaneous bacterial peritonitis (sbp) is a bacterial infection of the ascitic fluid and is diagnosed based on the following criteria: the presence of more than 250 neutrophils in ascitic fluid, which is not associated with surgery or an intraabdominal origin of infection in liver cirrhosis patients.2,3 sbp is the most common type of infection in hospitalized cirrhotic patients, occurring in about 9% of cases and accounting for about 25% of all infections.4 about 10% of cirrhotic patients with ascites may develop sbp within a year.5 despite the use of sensitive methods, only 39-41% of culture-positive sbp are in korean patients with sbp compared to around 60% in western studies.1,6,7 among positive culture results, both gram positive and negative organisms can be isolated, the more common being gram negative. |
| PubMedID- 25736154 | Letter: proton pump inhibitors - severity of liver disease and mortality in patients with cirrhosis - authors' reply. |
| PubMedID- 21743215 | Hcv is a major cause of chronic liver disease that may lead to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 26247932 | Hepatitis b virus (hbv) attacks the liver and can cause both acute as well as chronic liver diseases which might lead to liver cirrhosis and hepatocellular carcinoma. |
| PubMedID- 23339829 | cirrhosis is a consequence of chronic liver disease commonly caused by alcoholism, viral hepatitis, autoimmune disorders, or other aetiologies. |
| PubMedID- 24815066 | In some ccm cases the cardiac dysfunction in cirrhosis is not associated with the liver disease severity [30]. |
| PubMedID- 24376343 | The beneficial effects of a virologic response to entecavir in preventing progression of liver disease in patients with and without cirrhosis have also been observed in a study from taiwan.45 further, a virologic response to entecavir reduced the risk of clinical events and hepatocellular carcinoma in nucleos(t)ide-experienced patients with prior lamivudine-resistant or adefovir-resistant mutants, but not in nucleos(t)ide-naïve patients or nucleos(t)ide-experienced patients who had never developed lamivudine-resistant or adefovir-resistant mutants. |
| PubMedID- 25588648 | According to the world health organization (who), about 3 % of the world’s population has been infected with this virus and nearly 80 % of the infected individuals develop chronic liver disease, leading to liver cirrhosis and, in some cases, to hepatocellular carcinoma (who 2014). |
| PubMedID- PMC3580826 | Hepatitis d virus (hdv) coinfected with hbv is most often associated with a severe and progressive liver disease leading to cirrhosis more rapidly than hepatitis b alone and are more resistant to standard antiviral drugs (51). |
| PubMedID- 21552420 | Alcoholic hepatitis, nonalcoholic steatohepatitis, and viral hepatitis are the 3 major causes of chronic liver diseases, leading to liver fibrosis, cirrhosis, and the end-stage of hepatocellular carcinoma. |
| PubMedID- 24093051 | Pre-operative liver function tests should be performed in those with established cirrhosis or a history of liver disease, or excessive alcohol intake [18]. |
| PubMedID- 22760651 | The addition of hdv to an hiv/hbv coinfection is associated with a particularly aggressive course of liver disease, frequently leading to cirrhosis, decompensation, and death. |
| PubMedID- 20518553 | Liver fibrosis or cirrhosis is one of the representative liver diseases with a high morbidity and mortality worldwide. |
| PubMedID- 22921634 | The diagnosis of asymptomatic cirrhosis in patients with liver disease is of importance to start screening for complications in due time. |
| PubMedID- 26025214 | Idiopathic non-cirrhotic portal hypertension (incph) is a rare disease characterized by of intrahepatic portal hypertension in the absence of cirrhosis, other causes of liver disease and splanchnic venous thrombosis [1–7]. |
| PubMedID- 24714782 | Any chronic liver disease can lead to cirrhosis, characterized histologically by extensive fibrosis and the conversion of normal liver architecture into structurally abnormal nodules [1]. |
| PubMedID- 26121590 | cirrhosis is a consequence of chronic liver diseases, characterized by liver injury, chronic inflammation and finally by progressive substitution of liver parenchyma by scar tissue. |
| PubMedID- 24215040 | Conclusion: coffee drinking is associated with a reduced prevalence of cirrhosis in patients with chronic liver disease. |
| PubMedID- 25977695 | According to our findings, we recommend correction of vitamin d level in chronic liver disease, especially in patients with cirrhosis to maintain their bone density. |
| PubMedID- 24367208 | It is intriguing that all chronic liver diseases eventually lead to liver cirrhosis and the sequence of steatosis, steatohepatitis and fibrosis/cirrhosis is generally accepted as causative. |
| PubMedID- 25066318 | In these patients, continual inflammatory activity can cause significant fibrosis, cirrhosis, decompensation of the liver disease, or hepatocarcinoma. |
| PubMedID- 26424404 | Consequently, the development of end-stage liver disease (esld) with cirrhosis and hepatocellular carcinoma occurs at a younger age in co-infected individuals [16]. |
| PubMedID- 20171943 | Nonalcoholic steatohepatitis patients should undergo periodic evaluation of cardiovascular risk and of advancement of their liver disease; those with nonalcoholic steatohepatitis-cirrhosis should be evaluated for early diagnosis of hepatocellular carcinoma. |