PedAM
Pediatric Disease Annotations & Medicines
| Disease | cleft lip |
| Phenotype | |cleft palate |
| Sentences | 332 |
| PubMedID- 25045080 | Background: the etiology of nonsyndromic cleft lip with or without cleft palate (nscl/p) is very complex and still not well elucidated. |
| PubMedID- 24446087 | Analysis of susceptibility polymorphisms for nonsyndromic cleft lip with or without cleft palate in the brazilian population. |
| PubMedID- 22520921 | cleft lip with or without cleft palate (clp) and cleft palate only (cpo) are common birth defects of complex and heterogeneous aetiology. |
| PubMedID- 25322573 | Objective: to assess the association between polymorphism of methylenetetrahydrofolate reductase (mthfr) gene c677t locus and nonsyndromic cleft lip with or without cleft palate (nscl/p) in shanxi province of china. |
| PubMedID- 22906393 | Dermatoglyphic evaluation in subjects and parents of cleft lip with and without cleft palate. |
| PubMedID- 22043487 | We carried out association analysis of snps in these six candidate chromosomal regions in 128 nonsyndromic cleft lip with or without cleft palate cases and 105 controls from the rift valley of kenya. |
| PubMedID- 26331285 | The etiology of cleft lip with or without cleft palate (cl+/-p) is complex and heterogeneous, and multiple genetic and environmental factors are involved. |
| PubMedID- 21781441 | Study of the 12q13 region in nonsyndromic cleft lip with or without cleft palate. |
| PubMedID- 22522387 | Background: nonsyndromic cleft lip with or without cleft palate (nscl/p) is a common congenital malformation associated with genetic and environmental risk factors. |
| PubMedID- 24265584 | The cleft phenotype was divided into two sub-phenotypes such as cleft lip with or without cleft palate (74 clp) and cleft palate only (nine cpo). |
| PubMedID- 24859337 | cleft lip with or without cleft palate (cl/p) is one of the most common congenital malformations observed in humans, with 1 occurrence in every 500-1,000 births. |
| PubMedID- 24066709 | Objective : the aim of this work was to fine-map the region 6q23.1, which obtained suggestive linkage signal (logarithm of the odds [lod] score = 2.22 under a recessive model) to cleft lip with or without cleft palate (cl+/-p) in our previous genome-wide linkage scan to identify possible genetic variants that may contribute to cl+/-p. |
| PubMedID- 21176594 | [the correlation analysis between environmental factors, bone morphogenetic protein-4 and transforming growth factor beta-3 polymorphisms in nonsyndromic cleft lip with or without cleft palate]. |
| PubMedID- 22144845 | The cleft lip, with or without cleft palate, is more common than in tcs. |
| PubMedID- 24862802 | Conclusion: cleft lip with/without cleft palate and ventricular septal defects were significantly associated with a lower socioeconomic level. |
| PubMedID- 22887868 | Nonsyndromic cleft lip with or without cleft palate (nscl/p) is a complex disorder with a worldwide incidence estimated at 1:700. |
| PubMedID- 21248356 | cleft lip with cleft palate, ankyloglossia, and hypodontia are associated with tbx22 mutations. |
| PubMedID- 25538779 | All patients had midline cleft palate, 29.6% of them had cleft lip too that was repaired previously. |
| PubMedID- 20949506 | Revisiting the recurrence risk of nonsyndromic cleft lip with or without cleft palate. |
| PubMedID- 23631673 | According the international perinatal database report on typical oral clefts, the prevalence of cleft lip with or without cleft palate from 54 registries in 30 countries over at least 1 complete year during the period 2000 to 2005 was 9.92 per 10,000 births, which was lower than our finding [40]. |
| PubMedID- 21683068 | Single-nucleotide polymorphisms (snps) of the irf6 and tfap2a in non-syndromic cleft lip with or without cleft palate (nsclp) in a northern chinese population. |
| PubMedID- 26123647 | Rare variants in the epithelial cadherin gene underlying the genetic etiology of nonsyndromic cleft lip with or without cleft palate. |
| PubMedID- 25953455 | Objective: non-syndromic cleft lip, with or without cleft palate (nscl/p) is a common craniofacial birth defect, characterised by an incomplete separation between nasal and oral cavities without any other congenital anomaly in humans. |
| PubMedID- 26042903 | The anomalies and physical features that are discussed include birth parameters, aplasia cutis congenita, holoprosencephaly, asymmetric crying facies, preauricular ear tags and pits, cleft lip with or without cleft palate, esophageal atresia/tracheoesophageal fistula, congenital heart defects, ventral wall defects, and polydactyly. |
| PubMedID- 19839778 | Nonsyndromic cleft lip with or without cleft palate (nsclp) is one of the most common birth defects in humans with both genetic and environmental components involved in its expression. |
| PubMedID- 26221921 | Objective: nonsyndromic cleft lip with or without cleft palate (ns-cl/p) are among the most common congenital birth defects worldwide. |
| PubMedID- 25395774 | The cleft lip, with or without cleft palate is more common than in tcs. |
| PubMedID- 21131253 | Meta-analyses summarizing risk estimates for exposure to five pollutants and risk of cleft lip with or without cleft palate and cleft palate alone were all close to one, and none reached statistical significance (table 3). |
| PubMedID- 26343712 | A preconception period means one month before conception; or, odds ratio; ci, confidence interval; statistical significance values are given in bold; cl/p, cleft lip with or without cleft palate; cpo, cleft palate only. |
| PubMedID- 23921572 | Nonsyndromic cleft lip with or without cleft palate (nscl/p) is a common congenital deformity, often associated with missing or deformed teeth. |
| PubMedID- 23991581 | [association between single nucleotide polymorphism in wnt3 and nonsyndromic cleft lip with or without cleft palate in hui and han population of ningxia autonomous region]. |
| PubMedID- 23380913 | Beginning in 2006, new recruitment was limited to cases of cleft lip with or without cleft palate, and cases with cleft palate only were no longer enrolled. |
| PubMedID- 22455396 | The poliovirus receptor related-1 (pvrl1) gene encodes nectin-1, a cell-cell adhesion molecule (omim #600644), and is mutated in the cleft lip with or without cleft palate/ectodermal dysplasia-1 syndrome (clped1, omim #225000). |
| PubMedID- 24097855 | We tested hypotheses that maternal exposure during the periconceptional period to multivitamins or liver consumption would decrease cleft lip with or without cleft palate (cl +/- p) risk and that menstrual regulation supplements would increase cl +/- p risk. |
| PubMedID- 24437584 | Objective: nonsyndromic cleft lip with or without cleft palate (nscl+/-p) is a common craniofacial anomaly of complex etiology in people. |
| PubMedID- 23509905 | Association between interferon regulatory factor 6 gene polymorphisms and nonsyndromic cleft lip with or without cleft palate in a chinese population. |
| PubMedID- 21281326 | Based on our data, maternal gravidity represents a significant risk factor for congenital heart defects and cleft lip with or without cleft palate in the newborn infant. |
| PubMedID- 24559046 | Results: we detect a strong signal of increased prevalence of isolated cleft lip with or without cleft palate in a single region of poland, the dolnoslaskie voivodeship. |
| PubMedID- 25105440 | Nonsyndromic cleft lip with or without cleft palate (nsclp) is a common congenital deformity, often associated with folate deficiency. |
| PubMedID- 26469673 | Objectives: we determined the association between maternal neighborhood socioeconomic position (sep) and the risk of cleft lip with or without cleft palate (cl+/-p) or cleft palate alone (cp) in offspring. |
| PubMedID- 22905623 | Objective: to reveal the association between the single nucleotide polymorphism (snp) of v-maf musculoaponeurotic fibrosarcoma oncogene homolog b (mafb) gene rs17820943 locus and non-syndromic cleft lip with or without cleft palate (nscl/p) in the southern chinese han population. |
| PubMedID- 20569073 | The presence of cleft lip with or without cleft palate (cl/p) in family members of cancer patients was investigated. |
| PubMedID- 22909240 | Since the 1980s, prenatal detection of cleft lip with or without cleft palate (clp) is possible with a transabdominal ultrasound. |
| PubMedID- 21564312 | New evidence for the role of cystathionine beta-synthase in non-syndromic cleft lip with or without cleft palate. |
| PubMedID- 23940636 | Nonsyndromic cleft lip with or without cleft palate (nscl/p) are common birth defects with a complex etiology. |
| PubMedID- 23874873 | In contrast, for many common defects, including hypospadias, pyloric stenosis, cleft lip with or without cleft palate, and hydrocephalus, cancer risk was not increased compared to the reference cohort. |
| PubMedID- 24516586 | The prevalence of cp is about 1/2500 live births, much lower than the 1/1000 live births prevalence for nonsyndromic cleft lip with or without cleft palate (cl/p). |
| PubMedID- 23227324 | Although cleft lip with cleft palate and cleft lip only are usually grouped into the same category, dixon et al. |
| PubMedID- 26454948 | Objective: to explore the relationship between polymorphism of interferon regulatory factor 6 (irf6) gene rs642961 locus and nonsyndromic cleft lip with or without cleft palate (nscl +/- p). |
| PubMedID- 23510002 | Cl/p: cleft lip with or without cleft palate; cp: cleft palate only; nscl/p: non-syndromic cl/p; vws: van der woude syndrome; pps: popliteal pterygium syndromes; pcr: polymerase chain reaction; dhplc: denature high performance liquid chromatography; mlpa: multiplex ligation-dependent probe amplification. |