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PedAM

Pediatric Disease Annotations & Medicines




Disease cardiomyopathy
Phenotype |heart failure
Sentences 239
PubMedID- 22973525 During the course of the disease cardiomyopathy leading to congestive heart failure may develop [4].
PubMedID- 23597573 Background: the hallmark of trypanosoma cruzi infection is cardiomyopathy that leads to end-stage heart failure.
PubMedID- PMC3559817 To quantify myocardial deformation with two-dimensional feature tracking cardiac magnetic resonance (cmr) in patients with heart failure due to non-ischemic cardiomyopathy and in healthy controls.
PubMedID- 21757167 Methods: twelve consecutive patients with end-stage heart failure due to nonischemic dilated cardiomyopathy (dcm) (n = 6) and ischemic dilated cardiomyopathy (icm) (n = 6) who underwent svr were studied.
PubMedID- 22764179 Although progressive and debilitative ataxia is the most prominent clinical finding, hypertrophic cardiomyopathy with heart failure is the most common cause of early death in this disease.
PubMedID- 23346437 Neonatal cardiomyopathy often lead to fatal heart failure, although may eventually progress into a dilated form [2], into noncompaction of left ventricle, improve or even regress completely [3].
PubMedID- 21812510 Early diastolic dysfunction and focal fibrosis proceed to dilated cardiomyopathy (dcm), complicated by heart failure and arrhythmia in most patients.
PubMedID- 26097733 One major adverse consequence of pathological tachycardia is development of cardiomyopathy with subsequent heart failure.
PubMedID- 19910801 A 30-year-old african-american man with a history of end-stage heart failure due to idiopathic dilated cardiomyopathy underwent orthotopic cardiac transplantation.
PubMedID- 26471898 Only taking a subset of heart failure patients with cardiomyopathy, another american study showed the prevalence of malnutrition to be about 50 % that may not be directly comparable with our study which included various causes of heart failure which contribute to higher prevalence of malnutrition [39].
PubMedID- 22073308 We collected heart samples from 4 receipts of heart transplantation who suffered from dilated cardiomyopathy with end-stage heart failure, and 9 patients undergoing mitral valve replacement, as well as 4 normal hearts of traffic accident victims.
PubMedID- 20970284 A diagnosis of cardiomyopathy with acute heart failure, secondary to valvular heart disease, was secured.
PubMedID- 24065222 Background: the differences in concentrations of biomarkers between heart failure patients with dilated cardiomyopathy (hf-d) and with ischemic cardiomyopathy (hf-i) have yet to be defined.
PubMedID- 22784245 Both extracellular and intracellular alterations in proteolytic activities are invariably seen in heart failure associated with hypertrophic cardiomyopathy, dilated cardiomyopathy, hypertensive cardiomyopathy, diabetic cardiomyopathy, and ischemic cardiomyopathy.
PubMedID- 25653704 They can manifest as subclinical myocardial dysfunction or dilated cardiomyopathy with overt heart failure.8)9) anthracyclines, widely used for childhood malignancies, are well documented cardiotoxic agents.
PubMedID- 22758613 Normal values are between 0.37 ± 0.05. several studies have correlated tei index with clinical severity of heart failure in patients with dilated cardiomyopathy, cardiac amyloidosis, and after an acute myocardial infarction.
PubMedID- 25242522 Besides the relatively well characterized skeletal muscle degenerative processes, dmd is also associated with a dilated cardiomyopathy that leads to progressive heart failure at the end of the second decade.
PubMedID- 24451296 Oncologic drugs have been associated with various off-target cardiovascular responses, including cardiomyopathy leading to heart failure, cardiac dysrhythmias, thromboembolic events, and hypertension.
PubMedID- 21833028 Anthracycline derivatives such as doxorubicin rank among the most potent antineoplastic drugs.1 however, an unresolved problem associated with their use is normal tissue damage, in particular their dose-dependent acute and delayed cardiotoxicity, which manifests as congestive heart failure due to cardiomyopathy in up to 20% of the patients.2, 3, 4 the formation of reactive oxygen species (ros), generation of peroxynitrite by nitric oxide synthases (nos) and/or inhibition of topoisomerase ii (topo ii) are discussed to be responsible for the cardiotoxic side effect of doxorubicin.4, 5, 6 co-administration of anthracyclines with the antioxidant dexrazoxane as a cardioprotectant is in dispute because the molecular mechanisms involved in anthracycline-induced cardiotoxicity, as well as the molecular effects of dexrazoxane are still unclear.7, 8, 9 moreover, it is under debate whether dexrazoxane has negative effects on the antitumor efficacy of anthracyclines.10, 11 doxorubicin-induced cardiac dysfunction has been related to the induction of inos leading to an increase in highly cytotoxic peroxynitrite.12 yet, pharmacological targeting of inos-mediated no production as cardioprotective strategy for anthracycline treatments is controversially discussed.
PubMedID- 26550569 Both children showed symptoms of heart failure due to hypertrophic cardiomyopathy and suffered from recurrent metabolic crises usually triggered by respiratory or other infections since birth.
PubMedID- 26221650 When untreated, this cardiomyopathy can lead to heart failure, one of many cardiovascular diseases (cvds).
PubMedID- 23580922 Ppcm is an idiopathic dcm cardiomyopathy with heart failure secondary to lv dysfunction occurring in the last month of gestation or in 5 months of delivery, where no other cause can be found.
PubMedID- PMC4055878 However, anthracyclines have profound consequences on the structure and function of the heart causing with time a cardiomyopathy that leads to intractable congestive heart failure [10].
PubMedID- 25961010 Induction of ankrd1 in dilated cardiomyopathy correlates with the heart failure progression.
PubMedID- 23998545 Background: dilated cardiomyopathy (dcm) is associated with heart failure and increased mortality and there is no reliable biomarker to estimate patients' prognosis.
PubMedID- 23537813 Background: cardiac amyloidosis due to amyloid fibril deposition in the heart results in cardiomyopathy (cmp) with heart failure (hf) and/or conduction disturbances.
PubMedID- 26400472 Cardiac ttr amyloidosis presents as progressive, ultimately fatal, heart failure owing to restrictive cardiomyopathy, is rarely suspected and is usually misdiagnosed as coronary heart disease.
PubMedID- 23416015 Background: we set out to evaluate the utility of selected heart failure (hf) biomarkers in patients with dilated cardiomyopathy (dcm).
PubMedID- 23207078 Methods and results: l-arginine, adma, and symmetric dimethylarginine (sdma) were measured by liquid chromatography-tandem mass spectrometry in 341 patients with chronic heart failure due to dilated cardiomyopathy (dcm; n = 226) or ischemic cardiomyopathy (icm; n = 115).
PubMedID- 24130430 A single-chamber icd (current vr, st jude medical) had been implanted two years earlier for primary prevention while the patient was having symptoms of nyha class iii heart failure due to a dilated cardiomyopathy with left ventricular ejection fraction of 23%.
PubMedID- 23584065 Heavy alcohol consumption, however, often is associated with deterioration of heart muscle function (i.e., cardiomyopathy), which can lead to heart failure (lazarevic et al.
PubMedID- 24083195 The minor criteria are: 1) obesity and/or insulin resistance and/or type 2 diabetes; 2) history of dilated cardiomyopathy with congestive heart failure; 3) hearing loss; 4) hepatic dysfunction; 5) renal failure; 6) short stature; and 7) males: hypogonadism, females: irregular menses and/or hyperandrogenism.
PubMedID- 23923043 Indeed, in even an early review article, it had been mentioned that severe heart failure due to idiopathic dilated cardiomyopathy could be improved in patients receiving beta-blocker therapy starting at a very low dose and followed by a stepwise increase depending on the treatment duration [54].
PubMedID- 25784945 Dox, used in cancer patients, might induce cardiomyopathy, which can lead to heart failure [2, 31, 32].
PubMedID- 23540744 The response to modern heart failure therapy of cancer treatment-induced cardiomyopathy has never been evaluated in clinical trials, and currently there are no definitive guidelines.
PubMedID- 25379962 Conclusions: in heart failure patients with ischaemic cardiomyopathy, crt-d was associated with a mortality benefit compared with crt-p, but no benefit of crt-d over crt-p in mortality was observed in non-ischaemic cardiomyopathy.
PubMedID- 23652880 One case was dilated cardiomyopathy with heart failure, and the other showed echocardiographic features simulating hypertrophic obstructive cardiomyopathy.
PubMedID- 21105894 Coronary arteries were obtained from 17 patients with heart failure due to dilated cardiomyopathy of ischaemic origin in stage iii-iv of the new york heart association classification.
PubMedID- 25200106 In this study, dti was performed on left ventricular specimens collected from patients with chronic end-stage heart failure as a result of idiopathic dilated cardiomyopathy (n = 14) and from normal donors (n = 5).
PubMedID- 20802940 Conclusions: the results of the 6mwt in chagas-sah patients are similar to those verified in chagas cardiomyopathy patients with chronic heart failure.
PubMedID- 19181403 Hypertrophic obstructive cardiomyopathy (hocm) often leads to heart failure, severe ischemia, severe symptoms and death.
PubMedID- 22606396 Moreover, congestive heart failure due to dilated cardiomyopathy [8] can arise because of the cardiodepressant effect of anaesthesia and fluid overload.
PubMedID- 21739229 Although the infiltration of the heart from different types of amyloid results in restrictive cardiomyopathy that manifests with refractory congestive heart failure and conduction abnormalities, unequivocal identification of the deposited amyloidogenic protein is mandatory in order to avoid misdiagnosis and inappropriate treatment.
PubMedID- 26566415 Idiopathic peripartum cardiomyopathy presenting with heart failure is a true diagnostic and treatment challenge.
PubMedID- 24346072 Its cardiac manifestation, diabetic cardiomyopathy, leads to heart failure.
PubMedID- 23425518 The main indication for this procedure is severe heart failure due to amyloidotic cardiomyopathy in a patient without advanced neurologic involvement.
PubMedID- 20682064 The natural history of hypertrophic cardiomyopathy leads to heart failure and/or sudden death.
PubMedID- 23150834 This study provides new insights into investigation of a new therapy for pediatric dilated cardiomyopathy patients with advanced heart failure.
PubMedID- 25960594 A major limitation of anthracycline is the risk of cardiotoxicity, manifested as asymptomatic cardiac dysfunction in up to 57% [2, 3] and cardiomyopathy with subsequent clinical heart failure in up to 16% [4].
PubMedID- 21729325 Circulating levels of hfabp have a prognostic value regarding the future deterioration of congestive heart failure in patients with dilated cardiomyopathy [16,33], and persistently increased serum concentrations of hfabp predict adverse clinical outcomes in patients with shf [16].

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