PedAM
Pediatric Disease Annotations & Medicines
| Disease | c syndrome |
| Phenotype | |obesity |
| Sentences | 377 |
| PubMedID- 24567686 | As metabolic syndrome correlates directly with obesity andsedentary lifestyles, health education for patients is of significant importance in theself-management of risk factors, such as obesity, high blood pressure, and smoking10). |
| PubMedID- 26298466 | Thbs1 may act as a critical circulating factor that couples obesity with metabolic syndrome and diabetes in humans. |
| PubMedID- 25172520 | obesity with and without metabolic syndrome: do vitamin d and thyroid autoimmunity have a role. |
| PubMedID- 25191539 | obesity, which can lead to the metabolic syndrome, has recently gained attention as a factorthat dramatically increases the risk of arteriosclerotic disease. |
| PubMedID- 20414465 | Additionally, obesity and the presence of metabolic syndrome are related to increased insulin resistance in overweight and obese copd patients [59, 60]. |
| PubMedID- 23161371 | We have previously reported that obesity with features of metabolic syndrome (obesity, insulin-resistance, dyslipidaemia) decreases myocardial resistance to i-r compared with lean insulin-sensitive animals. |
| PubMedID- 20691130 | The aim of the present study was to elucidate whether enteric-coated lf (elf) might improve visceral fat-type obesity, an underlying cause of the metabolic syndrome. |
| PubMedID- 23533299 | The exact mechanisms that associate mitochondrial dysfunction, obesity, and aging with metabolic syndrome remain a topic of debate [17–22]. |
| PubMedID- 25586249 | obesity is associated with the metabolic syndrome. |
| PubMedID- 22582147 | Since in both vertebrates and in invertebrates δ9 desaturases has key function in cellular lipid partitioning and homeostasis it may be a potential target for therapeutic intervention to control obesity and other aspects of metabolic syndrome (dobrzyn and ntambi 2005). |
| PubMedID- 25830228 | While metabolic syndrome is often associated with obesity, 25% of humans suffering from it are not obese and the effect of physical activity remains unclear in such cases. |
| PubMedID- 21219375 | Visceral obesity, a pivotal characteristic of the metabolic syndrome, suppresses the hypothalamic-pituitary-testicular axis leading to diminished testosterone production. |
| PubMedID- 21078146 | Children were excluded if they had any genetic syndromes associated with obesity, including cerebral palsy, spina bifida, and hypothyroidism. |
| PubMedID- 20526390 | The high prevalence of metabolic syndrome may be attributed to abdominal obesity and dyslipidemia characterized by high triglycerides and low hdl cholesterol (table 3). |
| PubMedID- 23383064 | Metabolic syndrome is associated with visceral obesity, insulin resistance and an increased risk of cardiovascular diseases. |
| PubMedID- 21964613 | obesity is associated with the metabolic syndrome--a pathophysiologically distinct inflammatory process comprised of central obesity, insulin resistance, hypertension, and atherogenic dyslipidemia. |
| PubMedID- 22546774 | Background: fatty liver disease (fld) is characterized by increased intrahepatic triglyceride content with or without inflammation and is associated with obesity, and features of the metabolic syndrome. |
| PubMedID- 25875119 | A green algae mixture of scenedesmus and schroederiella attenuates obesity-linked metabolic syndrome in rats. |
| PubMedID- 24740690 | Particularly, due to the pathophysiological relevance of acc2 in lipid metabolic syndrome associated with obesity, diabetes, cancer, and cardiovascular disease, acc2 activity regulation has been considered as a candidate target for therapeutic interventions, which essentially requires authentic bioengineered recombinant proteins (abu-elheiga et al. |
| PubMedID- 24809933 | Accumulating evidence indicates that visceral fat obesity is located upstream of the metabolic syndrome and atherosclerosis910. |
| PubMedID- 25115695 | Hypertension, diabetes mellitus (especially type 2 diabetes mellitus) and metabolic syndrome associated with obesity are rapidly growing public health problems. |
| PubMedID- 26339468 | Today, the prevalence of visceral obesity associated with metabolic syndrome is two to ten times higher in women in many countries around the world [49–51]. |
| PubMedID- 22998948 | We have developed new dynamic tests to dissect the mechanisms regulating hpa axis central negative feedback sensitivity in humans, and demonstrated that this may be altered in obesity, one component of the metabolic syndrome. |
| PubMedID- 23465506 | Background: asthma has been linked to obesity and the presence of the metabolic syndrome. |
| PubMedID- 21187867 | Objective: the present community-based cross-sectional study was aimed to examine the association of metabolic syndrome (ms) with obesity measures, metabolic profiles, and intake of dietary fatty acids in asian indian population. |
| PubMedID- 23206662 | In humans, evidence suggests that the obesity-related morbidities associated with metabolic syndrome, including diabetes and cardiovascular disease, are caused by an increase in the production of advanced glycoxidation end-products (ages). |
| PubMedID- 25833179 | Lipodystrophy diagnosis can be challenging, and it has been suggested that partial forms can be easily misdiagnosed as common central obesity with associated metabolic syndrome. |
| PubMedID- 21270259 | Thus, available information suggests that obesity and other facets of metabolic syndrome involve deregulation of signaling pathways mediated by ppar. |
| PubMedID- 26389928 | Literature data suggest that the adpn/lep ratio is a sensitive risk indicator of metabolic syndrome in patients with overweight and obesity [35,66,67]. |
| PubMedID- 22846254 | Patients with sustained obesity and features of the metabolic syndrome had a worse 1-year mortality rate of 42%. |
| PubMedID- 22277141 | While obesity is associated with the metabolic syndrome, some obese individuals do not possess the constellation of the metabolic abnormalities and are referred to as metabolically healthy but obese (mho) persons. |
| PubMedID- 24524049 | Although authors introduced mfr (an index of smi corrected by visceral obesity) was independently associated with metabolic syndrome and arterial stiffness,[29] further study results are needed to the investigate effects of sarcopenic obesity on chronic metabolic disorders and cvd in older individuals. |
| PubMedID- 26107367 | Objectives: the aim of this study was to evaluate the efficacy of roux-en-y gastric bypass (rygb), compared with nonsurgical treatment (ns group), as an instrument for inducing remission of co-morbidities related to metabolic syndrome (mets) in patients with obesity, grades 2 and 3 (ob2,3). |
| PubMedID- 21941639 | Along with the obesity epidemic, the prevalence of metabolic syndrome (mets) has increased among children and adolescents [1, 2]. |
| PubMedID- 22303936 | How obesity causes symptoms of metabolic syndrome, in particular cardiomyopathies, is still largely unknown. |
| PubMedID- 23340319 | Dyslipidemia and glucose intolerance are, apart from hypertension and obesity, constituents of the so-called metabolic syndrome and of non-insulin-dependent diabetes mellitus. |
| PubMedID- 23556000 | Normal weight obesity is associated with metabolic syndrome and insulin resistance in young adults from a middle-income country. |
| PubMedID- 20514046 | Alstrom syndrome is a rare genetic syndrome associated with early-onset obesity, severe insulin resistance (ir) that is disproportionate to the degree of adiposity and premature diabetes. |
| PubMedID- 24334572 | Objective: both increased serum levels of low-density lipoprotein cholesterol (ldlc) and metabolic syndrome (mets) are associated with obesity and have been established to be risk factors of cardiovascular disease. |
| PubMedID- 25516385 | Studies in adult populations show that retinal microvascular changes are associated with obesity and components of the metabolic syndrome. |
| PubMedID- 20436743 | Diabetes, hypertension, metabolic syndrome, smoking, obesity, etc) remain similar to those described elsewhere in the world. |
| PubMedID- 24753685 | obesity, an essential component of metabolic syndrome which includes hypertension, diabetes mellitus, insulin resistance, and dyslipidemia, may contribute to cognitive impairment due to clustering with other vascular risk factors. |
| PubMedID- 26554109 | The aim of this study was to determine the relationships between serum adiponectin levels and parameters of both insulin sensitivity and obesity in patients with the metabolic syndrome and/or coronary artery disease, as well as to assess predictive value of adiponectin serum levels as a biomarker of these entitetis. |
| PubMedID- 24064364 | Epidemiological data indicate that an adverse maternal environment during pregnancy predisposes offspring to metabolic syndrome with increased obesity, and type 2 diabetes. |
| PubMedID- 21747976 | Angiotensinogen has also been suggested as a link between obesity and the development of the metabolic syndrome [67]. |
| PubMedID- 22935215 | Inappropriately low lh and fsh concentrations are prevalent in patients with obesity and other features of metabolic syndrome (hypertension and hyperlipidemia), this prevalence may be the result of insulin resistance at the level of the gonadotropin-releasing hormone (gnrh)-secreting neuron because insulin facilitates the secretion of gnrh from neuronal cell cultures [37]. |
| PubMedID- 20944981 | Central obesity is associated with osas and metabolic syndrome, and there is evidence that obstructive sleep apnea is an independent risk factor for obesity, glucose intolerance and insulin resistance. |
| PubMedID- 24060348 | Studies that investigated weight management in adults were obesity is attributed to specific genetic syndromes such as prader-willi syndrome, cohen syndrome or bardet-biedl syndrome were also excluded. |
| PubMedID- 21711372 | Objective: obesity is strongly associated with metabolic syndrome, but not all obese individuals display a clustering of metabolic risk factors. |
| PubMedID- 21842287 | It is a well-known fact that severe obesity is associated with the metabolic syndrome, type 2 diabetes, cardiovascular disease, hypertension, and other diseases. |