PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Phenotype | |obesity |
| Sentences | 117 |
| PubMedID- 24647890 | obesity was inversely associated with breast cancer among younger women and positively associated with risk for older women (interaction p < 0.0001). |
| PubMedID- 24676543 | Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and cpg island methylation of tumor suppressor genes. |
| PubMedID- 24118876 | To examine breast cancer relationships with obesity and central adiposity independently, our analytic strategy involved generating mutually adjusted risk estimates. |
| PubMedID- 25599228 | The local role of bat inflammation on the association of breast cancer with obesity has been recently analyzed in mice and humans [22,23], but it is still insufficiently understood and requires further examination. |
| PubMedID- 25361993 | obesity and the outcome of young breast cancer patients in the uk: the posh study. |
| PubMedID- 21878422 | Interaction between smoking and obesity and the risk of developing breast cancer among postmenopausal women: the women's health initiative observational study. |
| PubMedID- 21071885 | obesity increases the risk of breast cancer in postmenopausal women through a hormonal mechanism involving the metabolism of an androgenic precursor to estrogen in adipose tissue,24,25 and estrogen influences breast parenchyma proliferation.20,26–28 thus, obesity may be involved in the associations of hdl-c with mammographic density and breast cancer. |
| PubMedID- 26284118 | A long-lasting paradigm was born: obesity increases the incidence of postmenopausal breast cancer by causing persistently elevated adrenal oestrogen levels. |
| PubMedID- 26518195 | obesity, ethnicity, and quality of life among breast cancer survivors and women without breast cancer: the long-term quality of life follow-up study. |
| PubMedID- 22664497 | Many of the mechanisms that have been proposed to link obesity with breast cancer could be altered by ethnic factors8. |
| PubMedID- 25923423 | Many possible mechanisms have been proposed to explain the increased risk of breast cancer associated with obesity such as increased lipids and lipid signaling, inflammatory responses, insulin resistance, adipokines, altered immune responses, and oxidative stress. |
| PubMedID- 24489874 | Yet, in japanese women, evidence has shown that breast cancer risk with post-menopausal obesity was modified by pr status alone, not by er status [7]. |
| PubMedID- 21357383 | No association of risk variants for diabetes and obesity with breast cancer: the multiethnic cohort and page studies. |
| PubMedID- 23829168 | Both cohort and case–control epidemiological observations have demonstrated the association of metabolic syndrome, obesity and diabetes with increased breast cancer risk [5,6]. |
| PubMedID- 26560078 | Whether the effect of irisin on breast cancer can be attributed to obesity-related hyperinsulinemia and insulin resistance extends beyond the scope of this work, but is a particularly interesting field of research that is worthy of thorough investigation in future studies. |
| PubMedID- 24935119 | The increased risk of breast cancer that is associated with obesity has been widely reported; this has drawn much attention and as such, warrants investigation of the key mechanisms that link the obese state with cancer aetiology. |
| PubMedID- 23531051 | Our purpose was to determine if the associations of obesity with breast cancer-specific, all-cause, and non-breast cancer mortality differ between hispanic and non-hispanic white (nhw) women with breast cancer. |