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PedAM

Pediatric Disease Annotations & Medicines




Disease rhinitis
Phenotype |asthma
Sentences 154
PubMedID- 26553257 Among current asthmatics with current allergic rhinitis (n = 95), 68.8 % had partially controlled asthma or uncontrolled asthma, including 51.6 % who received insufficient anti-asthmatic treatment.
PubMedID- 20459697 Exclusion criteria were asthma, a history of perennial (persistent) allergic rhinitis or a positive skin prick test to perennial allergens, and other chronic nasal disease or major nasal structural abnormalities.
PubMedID- 22027192 Patients with asthma are often complicated by allergic rhinitis, and the intimate pathophysiological association between allergic rhinitis and asthma often imposes a significant morbidity on affected individuals.
PubMedID- 21047654 Results: some 75% (n=4,212) of the asthmatic patients presented with additional rhinitis and these were characterised as being both younger (41.3 vs 50.4 years; p<0.0001) and with less severe asthma (fev(1)=86.6 vs 79.3%, p<0.0001) than asthmatic patients without rhinitis.
PubMedID- 24508951 A positive impact of omalizumab on rhinitis in patients with both asthma and rhinitis was detected.
PubMedID- 24958195 Results: in the analysis adjusted for the presence of asthma, children with rhinitis had significantly higher ahr (p = 0.001).
PubMedID- 21747872 Concomitant occupational contact urticaria was verified by the cutaneous exposure test in 2/4 of them and occupational rhinitis together with asthma in one of them in the specific bronchial provocation test.
PubMedID- 20444152 In conclusion, current rhinitis is closely associated with conjunctivitis, asthma, atopic eczema, and bhr in childhood.
PubMedID- 23372205 Duc et al.,[27] has also found total house dust to be the most common allergen in patients of rhinitis with bronchial asthma followed by grass pollens, hdm, and animal dander.
PubMedID- 25744770 Results: peripheral blood th9 cells percentage was increased in allergic asthma group compared with allergic rhinitis and control group (0.74%+/-0.32% vs.
PubMedID- 24220581 The proportion of asthma cases associated with rhinitis was higher among the patients from the allergy-immunology service (p = 0.0001), whereas the patients from the pneumology service were older, had asthma for a longer duration, experienced more severe asthma and had a greater prevalence of overweight/obesity (p = 0.02, p = 0.04, p = 0.01 and p = 0.01, respectively).
PubMedID- 23587331 Sublingual immunotherapy (slit) is recommended in south africa for the treatment of allergic rhinitis (with or without asthma) to house dust mites or grass pollens.
PubMedID- 24282527 This suggests that parts of the differences between healthy upper and lower airways is attributed to the genes of this cluster, and that both allergic rhinitis with or without asthma affect these healthy differences in gene expression between upper and lower airways.
PubMedID- 26340660 For instance, apart from a higher prevalence of allergic rhinitis in patients with asthma [1], recent studies have further shown that chronic rhinosinusitis (crs) was fairly common in patients with bronchiectasis [2] and posed adverse impacts on lung function [2], quality of life [3,4] and the lost sense of smell [4,5].
PubMedID- 22931550 Association between upper airway diseases and asthma was stronger in patients with both rhinitis and sinusitis (crude or 9.34, 95%ci 4.75-18.35 and adjusted or 13.93, 95%ci 6.60-29.44, table2).
PubMedID- 22096535 Of the total, 279 (78.5%) patients were suffering from rhinitis, 11 (3.5%) with asthma and 65 (18.0%) were suffering from both.
PubMedID- 20398996 Temporal relationship of allergic rhinitis with asthma and other co-morbidities in a mediterranean country: a retrospective study in a tertiary reference allergy clinic.
PubMedID- 20945606 Conclusion: rhinitis was frequently associated with asthma in children consulting for the first time at allergy departments.
PubMedID- 21966601 Treatment of allergic rhinitis in patients with concomitant asthma has also been shown to improve both asthma and rhinitis control.
PubMedID- 22719812 Nonasthmatic patients with allergic rhinitis often have bronchial hyperresponsiveness and asthma develops most commonly in patients with rhinitis than in those without [14, 15].
PubMedID- 22950032 The prevalence of allergic rhinitis in adults with asthma was reported to be 60%-80% in korea,32 and this condition was also closely associated with more frequent asthma attacks, er visits, and poor asthma control.33,34 elderly women with asthma were particularly likely to have weakened bone structures after a 6-month treatment regimen with ics, this was replicated in our data (degenerative arthritis and/or osteoporosis, 71.2% in female vs. 28.6% in male, p<0.001).35 these findings suggest that comorbid conditions are common among elderly patients with asthma and that evaluation and proper control of these conditions will improve asthma control in this population.
PubMedID- 21337905 Methods: in a prospective observational study, health-related quality of life was assessed with the german adapted version of a new specific questionnaire (rhinasthma gav) in patients with allergic rhinitis with or without mild to moderate asthma due to grass, cereal, and/or rye pollen who were treated with seasonal high-dose slit with standardized allergen extracts.
PubMedID- 25201243 Results: at 8 yr of age, high bmi (>85th percentile), sensitization, and rhinitis were significantly associated with late-onset asthma (p < 0.05).
PubMedID- 23394514 The differential diagnosis for poorly responsive disease includes severe persistent asthma with associated allergic rhinitis, cardiac disorders such as left ventricular failure or mitral stenosis, vocal cord dysfunction, gastroesophageal reflux disease, recurrent aspiration, chronic obstructive pulmonary disease, emphysema, alpha-1-antitrypsin deficiency, sarcoidosis, hypersensitivity pneumonitis, bronchiectasis, allergic bronchopulmonary aspergillosis, airway neoplasm, and churg-strauss vasculitis.
PubMedID- 26122503 In the 3c cohort study, abdominal obesity and allergic rhinitis were positively associated with asthma.23 in cross-sectional studies, several factors have been associated with current prevalence (usually defined as "the presence of asthma within the past 12 months") in the elderly, including ahr,24 smoking,25 rhinitis,2627 or sarcopenic obesity.28 methacholine ahr exhibits a bimodal age distribution in the general population, increasing in the elderly, and may contribute to accelerated lung function decline and the development of asthma in later stages of life.2930 the association between rhinitis and asthma was also observed in nonatopic subjects.26 however, to the best of our knowledge, no genetic factor influencing asthma in the elderly has yet been reported, unlike the situation with childhood disease.
PubMedID- 20502102 Peripheral eosinophil counts were significantly higher only in asthma with rhinitis (p<0.005).
PubMedID- 24075536 This may have implications for the therapy of seasonal allergic rhinitis with and without asthma in terms of promoting long-term anti-inflammatory treatment.
PubMedID- 25893026 Furtehrmore, the attempt to estimate atopy as a risk factor for developing asthma alone, or coincidence of asthma and rhinitis, showed that there was a significant diference in having asthma, and the combination of asthma and rhinitis together, related to the presence of atopy.
PubMedID- 21761714 Method: genmapp software was used to analyze the expression profile of nasal mucosa of seasonal allergic rhinitis(sar) and sar associated with asthma of oligonucleotide microarray (affymetrix hg-u133-plus2).
PubMedID- 24284354 By contrast, only maternal and paternal history of asthma with allergic rhinitis predicted peanut allergy in the infant.
PubMedID- 23935740 A previous study demonstrated that asthma or a history of allergic rhinitis, previous nose surgery and nasal polyps are adverse prognostic factors of ess (4).
PubMedID- 23130330 The nasal cavity is connected to the bronchus by a single airway passage, and rhinitis is frequently associated with co-morbidities like asthma, which suggests the concept "one airway one disease".
PubMedID- 24396984 The studies thus far available showed that this treatment, in both forms of subcutaneous immunotherapy (scit) and sublingual immunotherapy (slit) is able to prevent the development of asthma in patients with allergic rhinitis and the occurrence of new sensitizations in patients monosensitized.
PubMedID- 24446919 After adjusting for smoking habits and a wide range of established and potential vascular risk factors, rhinitis without asthma was associated with intermittent claudication (rrr:4.63, 95% ci:1.72-12.5), whereas no significant association was found with asthma alone (rrr:1.45, 95% ci:0.27-7.76) or asthma-rhinitis overlap (rrr:2.89, 95% ci:0.91-9.18).
PubMedID- 22321178 In the survey, asthma combined with allergic rhinitis had the highest rate, 49.54%, 50.14%, 34.83%, respectively in the 3 cities.
PubMedID- 20846390 This first clinical study of immunotherapy using a purified natural alt a1 (the major a alternata allergen) for the treatment of allergic rhinitis with or without asthma demonstrated the good tolerance of the preparation, together with the induction of strong allergen-specific igg4 antibody responses.
PubMedID- 24734195 It is of note that the prodromal phase of css is characterized by adult onset asthma associated with rhinitis, sinusitis, nasal polyps, and eosinophilia.
PubMedID- 23302264 The prevalence of asthma in patients with rhinitis could reach up to 40%, and the majority of patients with asthma experience rhinitis symptoms [1].
PubMedID- 21507261 Thirty-two non-smoking subjects were recruited: 19 had mild stable asthma associated with allergic rhinitis (a) and 13 had allergic rhinitis without asthma (r).
PubMedID- 25403637 In an attempt to evaluate the association, a review of all articles that were published in the last 10 years which referred to the relation of childhood rhinitis with asthma were analysed, whereas the recent knowledge on physiology and phenotype was reported as background.
PubMedID- 22405116 Despite a high prevalence of both gastro-oesophageal reflux and allergic rhinitis among patients with asthma, treatment with proton-pump inhibitors or nasal corticosteroids does not reduce the rate of asthma exacerbations.
PubMedID- 25553262 In a multiple logistic regression model, rhinoconjunctivitis produced a twofold independent risk for current asthma with respect to rhinitis alone, which was larger than the risk produced by allergic sensitization, parental history for asthma, and heavy traffic (table 6).
PubMedID- PMC4082151 In the multivariate models adjusted for the use of intranasal and inhaled corticosteroids as well as antihistamines, asthmatic children with current rhinitis remained markedly and significantly more likely to have frequent asthma exacerbations (>2 per year; or[95%ci], 12.0 [2.12-67.92], p=0.005, aor, 4.75 [1.54-14.65], p=0.007).
PubMedID- 24367833 Objective: to investigate the cost-effectiveness of standardized specific immunotherapy (sit) for allergic rhinitis patients accompanied with asthma (aras) in china.
PubMedID- 24404392 Compared to asthma patients, subjects with allergic rhinitis were more sensitized to allergens.13,25 moreover, sensitization to outdoor allergens is associated with allergic rhinitis, rather than asthma;13,18 in particular, pollens were major sensitizing allergens in patients with allergic rhinitis.13,34 factors that influenced the clinical significance of aeroallergens include concentration, particle size, and exposure duration of the aeroallergens.35,36 airborne pollens with diameters larger than those of house dust mite particles may not reach the lower respiratory tract; however, conjunctival and upper respiratory tract mucosa can be exposed to large amounts of aeroallergens, even large allergens such as pollens.
PubMedID- 22073091 Bronchial asthma in patients with allergic rhinitis) and the expansion of sensitization can be limited.
PubMedID- 25430949 Additionally, occupational rhinitis can be associated with occupational asthma and upper airway symptoms may precede those of the lower respiratory tract.
PubMedID- 23379115 The different ages, living environment, family history, history of eczema and allergic rhinitis children with asthma were related with the pathogenesis and development of ar in childhood.
PubMedID- 25335629 Where rhinitis co-exists with asthma, it is a major risk factor for poor asthma control, which can have adverse effects on fetal development during pregnancy.
PubMedID- 22166078 Immunotherapy may also reduce the risk for the future development of asthma in patients with allergic rhinitis [5].

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