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PedAM

Pediatric Disease Annotations & Medicines




Disease proteinuria
Phenotype |nephropathy
Sentences 71
PubMedID- 23384747 According to recent guidelines, these contraceptives must be avoided in case of associated cardiovascular risk factors, cardiovascular disease or severe microvascular complications such as nephropathy with proteinuria or active proliferative retinopathy.
PubMedID- 24265571 Deaths usually occur secondary to nephropathy with proteinuria and malignant hypertensions.
PubMedID- 23331443 Conclusion: for early iga nephropathy patients with minimal proteinuria, normal blood pressure, and normal renal function, treatment with 2.5 mg/daily of ramipril for 5 years does not offer any benefit.
PubMedID- 22399858 33 in addition, some arbs may be more effective than others in reducing proteinuria in patients with diabetic nephropathy despite providing similar reductions in bp.34 nevertheless, the main renoprotective actions of arbs in general are largely mediated by their effects on bp.9 interestingly, the fda has not extended a general claim of nephroprotective benefits to all molecules in the arb class despite the fact that all approved arbs inhibit at1 signaling and lower bp.
PubMedID- 24455746 Podocyte loss due to apoptosis and podocyte dysfunction contributes to proteinuria in patients with diabetic nephropathy [55–57].
PubMedID- 26239462 Urinary ngal levels also correlated with the degree of proteinuria in patients with iga nephropathy [16] and membranous nephropathy [14,15].
PubMedID- 23199046 The unique predictive value of plasma ccn2 in the progression of diabetic nephropathy, particularly in patients with severe proteinuria, suggests that ccn2 could also be used as a biomarker not only in diabetic patients who are likely to develop clinical nephropathy, but also in those who will exhibit rapid disease progression despite receiving appropriate treatment (table 1).
PubMedID- 23741418 Emerging clinical and animal studies have demonstrated that vitamin d and its analog reduce proteinuria in patients with iga nephropathy [2], non-dialysed chronic kidney disease stage 4–5 [3], [4], diabetic nephropathy [5], and animal models such as subtotally nephrectomized model [6], diabetic nephropathy model [7], adriamycin-induced nephropathy [8], puromycin-induced nephropathy [9], [10].
PubMedID- 22803087 These patients were characterized by oxidative stress, diabetic nephropathy with associated proteinuria, and impairment of water excretion, electrolyte excretion, and nitrogen excretion in the kidneys.
PubMedID- 24886340 Remission of proteinuria in patients with idiopathic membranous nephropathy and nephrotic syndrome according to fe-igg level.
PubMedID- 19605553 The zucker fatty rats, a widely studied model of obesity and insulin resistance, exhibit glomerular hypertrophy, thickening of basement membranes and diffuse expansion of the glomerular mesangial matrix that resemble some of the histologic changes seen in diabetic nephropathy with proteinuria [6, 7].
PubMedID- 25984202 C1q nephropathy appears with proteinuria, usually within the nephrotic range.
PubMedID- 24721885 Conclusions: the findings in this cohort and previous studies suggest that rare cases of mild iga nephropathy with nephrotic range proteinuria exhibit a clinical presentation, biopsy findings, treatment response, and outcome more typical of iga nephropathy with superimposed minimal change disease.
PubMedID- 22675377 Professor guan [15] and li [16] treated nephropathy with severe proteinuria and edema in a prescription of ccd.
PubMedID- 21660304 The mechanisms might be due to development of proteinuria because of chronic allograft nephropathy and/or hcv-associated glomerulonephritis and ptdm.
PubMedID- 24131475 Conclusion: immunoglobulin a nephropathy patients with lower proteinuria had higher galnac exposure rates.
PubMedID- 24468233 They also develop diabetic nephropathy with proteinuria and focal glomerulosclerosis that end in renal insufficiency [6].
PubMedID- 26289088 Background: sometimes, acute and progressive proteinuria increases occur in patients with iga nephropathy (igan) after favorable long-term clinical courses of >10 years, but their clinical and histological characteristics are not well understood.
PubMedID- 24327929 Urinary nephrin mrna expression significantly correlated with the degree of proteinuria in patients with diabetic nephropathy, showing that nephrin mrna in the urine could possibly be clinically used as a biomarker to follow glomerulopathy progression in diabetic patients [87].
PubMedID- 23502465 Reported a down-regulation of nestin expression in fsgs, mn and iga nephropathy with proteinuria, and the glomerular nestin expression levels correlated inversely with the 24-hour urine protein results [11].
PubMedID- 25102693 Artemisinin ameliorated proteinuria in rats with adriamycin-induced nephropathy through regulating nephrin and podocin expressions.

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