PedAM
Pediatric Disease Annotations & Medicines
| Disease | portal hypertension |
| Phenotype | |cirrhosis |
| Sentences | 166 |
| PubMedID- 21485513 | Conclusion: the results indicated the effectiveness of therapy with flavonoids hesperidin with diasmin at portal hypertension in patients with alcoholic cirrhosis, which allows to include them in the complex treatment of medicamental prophylaxis of variceal bleeding. |
| PubMedID- 21176011 | Although poph is most commonly observed in the setting of cirrhosis, patients with non-cirrhotic portal hypertension are also at risk of developing the disorder. |
| PubMedID- 24697006 | In second pregnancy, medically induced abortion was performed in the 12th week because of deterioration of the underlying disease, liver cirrhosis with portal hypertension. |
| PubMedID- 24829653 | However the normal platelet count and serum albumin in the patient is not in favor of advanced cirrhosis as the cause of portal hypertension. |
| PubMedID- 25053449 | Liver collagen in cirrhosis correlates with portal hypertension and liver dysfunction. |
| PubMedID- 21843735 | Patients with recurrent complications or cirrhosis may die because of recurrent infection, portal hypertension, liver failure, or cholangiocarcinoma. |
| PubMedID- 20921950 | portal hypertension in cirrhosis depends on increased intrahepatic vascular resistance, which is explained by fibrosis and intrahepatic hyperresponsiveness to vasoconstrictors. |
| PubMedID- 21340026 | However, sorafenib can lead to endothelial injury and promote vascular leakage, and is not approved for patients with portal hypertension complicated by cirrhosis of the liver and advanced hcc (child–pugh class b to c), even in the absence of gastrointestinal bleeding. |
| PubMedID- 21802316 | Purpose: to develop a clinically relevant porcine model of liver cirrhosis with portal hypertension by means of hepatic transarterial embolization. |
| PubMedID- 25709491 | It has been identified as one of the leading causes of mortality, with close to 50,000 deaths attributed to it per year in the united states.1 the major morbidity from cirrhosis is due to portal hypertension, with formation of venous collaterals and marked circulatory as well as vascular abnormalities. |
| PubMedID- 22811587 | Hepatic manifestations were first described by klatskin and yesner in 1950 and include granulomatous hepatitis, cholestasis, cirrhosis, portal fibrosis leading to presinusoidal portal hypertension, budd-chiari syndrome, adult ductopenia-like syndrome, and rarely chronic granulomatous sclerosing cholangitis with ductal strictures [55–57]. |
| PubMedID- 24974920 | Evaluation of cardiac systolic and diastolic functions in liver cirrhosis patients with portal hypertension conventional was done by conventional doppler echocardiography and tdi. |
| PubMedID- 25457205 | Background & aims: inflammation, collagen deposition and tissue remodelling are involved in the pathogenesis and complications of cirrhosis with portal hypertension. |
| PubMedID- 26357616 | Liver damage can be progressive, leading to cirrhosis, complications of portal hypertension, and liver-related death, and, therefore, must be accurately identified. |
| PubMedID- 24889902 | Phg, by definition, requires the presence of portal hypertension, with or without cirrhosis, whereas gave requires neither cirrhosis nor portal hypertension. |
| PubMedID- 20562900 | Hepatic fibrosis and its endstage cirrhosis, with life-threatening complications of portal hypertension and liver failure, have become major public health problems1. |
| PubMedID- 25256370 | Background: decreased antithrombin iii (atiii) activity and large splenic vein diameter (svd) are risk factors for portal vein thrombosis (pvt) after splenectomy in liver cirrhosis with portal hypertension. |
| PubMedID- 25037870 | Hcc patients seemed to suffer from less severe or shorter duration of portal hypertension compared with child-pugh class-matched cirrhosis patients. |
| PubMedID- 23999681 | Combined biliovascular injuries, segmental atrophy, and secondary biliary cirrhosis with portal hypertension are special circumstances which are best managed by a multidisciplinary team at an experienced center for optimal outcomes. |
| PubMedID- 25417057 | Liver stiffness measurement (lsm) is frequently used as non-invasive alternative for liver fibrosis including cirrhosis, which can lead to portal hypertension. |
| PubMedID- 24563796 | Relevant diagnoses of the patient were (i) known hypertensive cardiac disease (transthoracic echocardiography 6 months before had shown a lv-ef of 54% and a light mitral and tricuspid insufficiency) and (ii) liver cirrhosis with portal hypertension. |
| PubMedID- 20653965 | Patent paraumbilical and abdominal subcutaneous veins are found frequently as collaterals in patients due to portal hypertension, mainly associated with liver cirrhosis [1,2]. |
| PubMedID- 21116340 | Patients with cirrhosis and signs of portal hypertension (platelet count <140,000/mm3) should have screening endoscopy. |
| PubMedID- 24400086 | The hemodynamic alteration of portal hypertension in patients with liver cirrhosis contributes to most of the clinical manifestations of the disease: gastrointestinal bleeding, hepatic encephalopathy, ascites and renal failure. |
| PubMedID- 23520531 | Ls is currently the best non-invasive surrogate predictor of portal hypertension in patients with cirrhosis [19], and its prognostic value was recently confirmed by cross-sectional studies about the presence of gastroesophageal varices [3], [20], [21] and longitudinal studies with hard clinical end-points such as the appearance of clinical decompensation and hepatocellular carcinoma [4], [5]. |
| PubMedID- 20300546 | To prevent immediate and late sequelae of hepatolithiasis, such as suppurative cholangitis, septicemia, secondary biliary cirrhosis with resultant portal hypertension, bleeding varices, and hepatic failure [5], aggressive treatment is needed. |
| PubMedID- 24439187 | The causes of ev included portal hypertension with cirrhosis in 52 cases (42 of hepatitis as dominant, 5 of alcoholic, 3 of biliary). |
| PubMedID- 26385087 | Thus, jak2 inhibitors, already in clinical use for other indications, might be a new approach to treat cirrhosis with portal hypertension. |
| PubMedID- 25543221 | Liver cirrhosis with portal hypertension is also associated with the presence of pahs in 1-2% of cases. |
| PubMedID- 24324910 | For a definitive diagnosis of hps, patients must meet three criteria: (1) room air po2 < 80 mmhg or a-a gradient > 15 mmhg, (2) evidence of intrapulmonary shunting (typically on contrast-enhanced echocardiography or a lung perfusion scan), and (3) portal hypertension with or without cirrhosis [1]. |
| PubMedID- 20652243 | Four patients underwent splenectomy because of liver cirrhosis with portal hypertension and gastroesophageal variceal bleeding. |
| PubMedID- 19918014 | We defined liver disease as one of the following: 1) abnormal liver function tests, 2) cirrhosis with portal hypertension, or 3) use of supplementary bile acids. |
| PubMedID- 20583425 | Background/aims: endosonography (eus) is rarely used in the routine diagnostic of portal hypertension in patients with cirrhosis even though it has significantly higher sensitivity for detection of varices than gastroduodenoscopy. |
| PubMedID- 20616408 | cirrhosis leads to portal hypertension which induces portosystemic collaterals, allowing gut-derived humoral substances to directly enter the systemic circulation without detoxification by the liver. |
| PubMedID- 25374709 | In view of a normal serology, the patient's diagnosis was alcohol-related cirrhosis with portal hypertension with portal colopathy with massive lower gi bleed. |
| PubMedID- 25969457 | Varices are known to develop in patients having cirrhosis with portal hypertension. |
| PubMedID- 25658710 | However, advanced liver disease, defined as multilobular cirrhosis frequently with portal hypertension, occurs in only 5–10% of individuals with cf [4,5,7]. |
| PubMedID- 24505457 | If untreated, ba progresses to cirrhosis, with portal hypertension and liver failure leading to death within two to three years. |
| PubMedID- 24587847 | Patients with nash have the potential to develop fibrosis and cirrhosis leading to portal hypertension, liver decompensation, and hepatocellular carcinoma [4]. |
| PubMedID- 22086533 | However, she developed hepatic cirrhosis with portal hypertension. |
| PubMedID- 23729979 | Portal vein interventions in liver transplant recipients represent a group of interventions in the management of several disease entities including portal vein stenosis, portal vein thrombosis, and recurrent liver cirrhosis with portal hypertension with and without gastric varices. |
| PubMedID- 25848469 | This review describes the recent developments in the pathobiology of endothelial dysfunction (ed) in the context of cirrhosis with portal hypertension and defines novel strategies and potential targets for therapy. |
| PubMedID- 26464566 | Rectal varices are not an uncommon manifestation in cirrhosis with portal hypertension [1]. |
| PubMedID- 23670970 | Liver disease was defined by clinician diagnosis in two studies (tss and cgs), whereas the gms study required documentation of portal hypertension attributable to cirrhosis (15). |
| PubMedID- 21701671 | She was a known case of cryptogenic liver cirrhosis with portal hypertension. |
| PubMedID- 24331694 | [non-invasive assessment of portal hypertension in patients with liver cirrhosis using fibroscan transient elastography]. |
| PubMedID- 21806953 | Conclusions: treating portal hypertension by tips in patients with advanced cirrhosis and without he had no effect on their cbf and seemed not to entail a risk of cerebral hypoperfusion. |
| PubMedID- 26192141 | The management of portal hypertension in cirrhosis has evolved over time, leading to improvements in the care and survival of patients with varices and variceal hemorrhage, particularly in patients who achieve a significant reduction in portal pressure. |
| PubMedID- 25561775 | Patient has a hcv cirrhosis with portal hypertension and esophageal varices f1. |
| PubMedID- 21827004 | Reconstructed cta images showed that different collateral vessels were developed at the end-stage of chronic liver cirrhosis due to severe portal hypertension. |