PedAM
Pediatric Disease Annotations & Medicines
| Disease | lung cancer |
| Phenotype | |brain metastases |
| Sentences | 91 |
| PubMedID- 24852190 | Human herpesvirus 6 encephalitis simulating brain metastases in a patient with advanced small-cell lung cancer. |
| PubMedID- 24772316 | The available treatment options for lung cancer with brain metastases (bm) are currently limited. |
| PubMedID- 22220151 | Because gefitinib is effective in treating brain metastases of lung cancer with egfr mutation [7], brain metastases may have been controlled in this case. |
| PubMedID- 24985049 | Limited treatment options are available for lung cancer with brain metastases. |
| PubMedID- 25556163 | Rapid response of brain metastases to alectinib in a patient with non-small-cell lung cancer resistant to crizotinib. |
| PubMedID- 21735751 | Clinical diagnosis of primary lung cancer with multiple brain metastases was made, and he underwent whole brain radiotherapy. |
| PubMedID- 26310285 | Herein, we conducted a self-controlled study to evaluate the effect of wbrt on the permeability of bbb in non-small cell lung cancer (nsclc) patients with brain metastases (bm). |
| PubMedID- 21772102 | This is an extremely rare case of small-cell lung cancer with multiple brain metastases in terms of showing a long- term remission. |
| PubMedID- 21697413 | Conclusion: radiobiological models suggest that if there is a non-uniform distribution of microscopic brain metastases in patients with small cell lung cancer, higher population-based metastasis-free rates might be achievable with non-uniform irradiation compared with the same integral whole-brain dose delivered as a uniform prescription. |
| PubMedID- 19962229 | Short-course whole-brain radiotherapy (wbrt) for brain metastases due to small-cell lung cancer (sclc). |
| PubMedID- 20009927 | Multimodality management of non-small cell lung cancer patients with brain metastases. |
| PubMedID- 20395118 | The management of brain metastases in patients with non-small cell lung cancer-is it time to go back to the drawing board. |
| PubMedID- 20728237 | Cisplatin, fotemustine and whole-brain radiotherapy in non-small cell lung cancer patients with asymptomatic brain metastases: a multicenter phase ii study of the gruppo oncologico italia meridionale (goim 2603). |
| PubMedID- 25583566 | Egfr tyrosine kinase inhibitors versus cranial radiation therapy for egfr mutant non-small cell lung cancer with brain metastases: a systematic review and meta-analysis. |
| PubMedID- 24197981 | Egfr mutation status and its impact on survival of chinese non-small cell lung cancer patients with brain metastases. |
| PubMedID- 23129122 | Background: this phase ii, open-label study evaluated the efficacy and safety of erlotinib as second-line therapy in non-small-cell lung cancer (nsclc) patients with brain metastases (bm). |
| PubMedID- 24376956 | Background and aim: long-term survival of lung cancer patients with brain metastases (bm) is very rare. |
| PubMedID- 24022905 | Long-lasting response to crizotinib in brain metastases due to eml4-alk-rearranged non-small-cell lung cancer. |
| PubMedID- 24577133 | Background: survival upon diagnosis of brain metastases (bm) in patients with non-small cell lung cancer (nsclc) is highly variable and established prognostic scores do not include tissue-based parameters. |
| PubMedID- 22430135 | Cxcr4 and cxcl12 immunoreactivities differentiate primary non-small-cell lung cancer with or without brain metastases. |
| PubMedID- 22917813 | This study was designed to determine if maintenance enzastaurin improved the outcome of whole brain radiotherapy (wbrt) in lung cancer (lc) patients with brain metastases (bms). |
| PubMedID- 25031274 | Background: median survival of non-small cell lung cancer (nsclc) patients with brain metastases is poor. |
| PubMedID- 24310312 | The outcome of bifocal surgical resection in non-small cell lung cancer with synchronous brain metastases: results of a single center retrospective study. |
| PubMedID- 22613339 | [progress of treatments in non-small cell lung cancer with brain metastases]. |
| PubMedID- 25619758 | Cancers included rcc (n = 5), glioblastoma (n = 4), and non-small-cell lung cancer with brain metastases (n = 1). |
| PubMedID- 21792167 | Combined treatment of non-small cell lung cancer with synchronous brain metastases: a single center experience. |
| PubMedID- 26336472 | Results of surgical treatment of primary lung cancer with synchronous brain metastases. |
| PubMedID- 23189011 | Sekine et al,[3] evaluated the correlation between non-small cell lung cancer patients with brain metastases and epidermal growth factor receptor (egfr) mutations on molecular studies, as well as the radiological findings. |
| PubMedID- 22818215 | A 69 year old lady has an extensive small cell lung cancer with newly diagnosed brain metastases. |
| PubMedID- 25780337 | Several seminal papers convinced many leading researchers that cscs are real in human cancers, notably breast,2 ovarian,3 brain metastases of lung cancer,4 pancreatic cancer,5 and glioblastoma.6 now there is vigorous activity in identifying or developing agents specifically capable of killing or suppressing cscs and in moving these agents through the clinical trial system rapidly. |
| PubMedID- 22678505 | A 74-year-old diabetic patient who had a history of non-small cell lung cancer with brain metastases and subsequent treatment with srs, presented with a focal lesion in the left centrum semiovale with progressively worsening edema. |
| PubMedID- 21224697 | We report two cases of lung cancer patients with postoperative solitary brain metastases obtaining long-term survival after gamma knife stereotactic radiosurgery. |
| PubMedID- 25247337 | Efficacy of the irreversible erbb family blocker afatinib in epidermal growth factor receptor (egfr) tyrosine kinase inhibitor (tki)-pretreated non-small-cell lung cancer patients with brain metastases or leptomeningeal disease. |
| PubMedID- 26182869 | Methods: lung cancer cases with brain metastases were retrospectively collected during 2002 and 2008 from shanghai chest hospital, shanghai jiao tong university. |
| PubMedID- 20636143 | Is "routine" cranial irradiation in hemiplegic lung cancer patients with brain metastases justified. |
| PubMedID- 23271367 | Though brain metastases, especially with lung cancer, melanoma and breast cancer, are becoming a common clinical problem, limited treatment options have existed [23], such as gamma knife radiosurgeries [24,25], stereotactic radiosurgery [26] or irradiation [27], uvc irradiation [28] and whole brain radiotherapy [29–31]. |
| PubMedID- 22933980 | Outcome of small cell lung cancer (sclc) patients with brain metastases in a routine clinical setting. |
| PubMedID- 23393579 | Primary tumor types vary in their propensity to form brain metastases (bm) with lung cancer, breast cancer and melanoma showing the highest incidences of central nervous system (cns) involvement. |
| PubMedID- 23392751 | [chemotherapy for small cell lung cancer with brain metastases]. |
| PubMedID- 23443093 | Recently established a spontaneous brain metastases model of lung cancer by surgical orthotopic implantation (soi) techenique, thus making it possible to mimic the initial process of malignancy metastasis. |
| PubMedID- 22335887 | Although the presence of epidermal growth factor receptor (egfr) mutation and good response to gefitinib have been reported in non-small cell lung cancer (nsclc) patients with miliary brain metastases, the influence of the egfr mutations on the radiographic features remains unclear. |
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