PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Phenotype | |hepatitis |
| Sentences | 144 |
| PubMedID- 21194431 | The underlying etiology of liver disease was attributed to hepatitis b virus (hbv) infection if patients were seropositive for hepatitis b surface antigen (hbsag, ria kits, abbott laboratories, north chicago, il, usa) and attributed to hepatitis c virus (hcv) infection if patients were seropositive for an antibody against hcv by a second-generation enzyme immunoassay (abbott laboratories, il). |
| PubMedID- 25457210 | Background & aims: genetic variants of patatin-like phospholipase domain-containing 3 (pnpla3) and diabetes are associated with liver disease severity, in patients with chronic hepatitis c (chc) infection. |
| PubMedID- 25578311 | Platelets are key elements in the pathogenesis of acute and chronic liver disease associated with hepatitis b virus (hbv) infection by promoting the accumulation of virus-specific cd8(+) t cells and nonspecific inflammatory cells into the liver parenchyma. |
| PubMedID- 22141390 | Entecavir: a review of its use in the treatment of chronic hepatitis b in patients with decompensated liver disease. |
| PubMedID- 24152445 | After stratification of our cohort, the association between the srebp1c variant and liver stiffness was replicated in the sub-cohort of patients with viral hepatitis, but not in patients with non-viral liver disease. |
| PubMedID- 25961570 | Reduced expression of ifnar1 has also been observed in the liver biopsies of chronic liver disease patients with hepatitis c virus infection [40]. |
| PubMedID- 22059164 | hepatitis a vaccination of patients with chronic liver disease admitted to hospital: a university of british columbia medical resident quality assurance pilot project. |
| PubMedID- 25532128 | The mechanisms whereby hdv leads to accelerated liver disease in hepatitis b virus (hbv)/hdv co-infected patients and the histological characteristics of chronic hepatitis d (chd) patients need further investigation. |
| PubMedID- 26182389 | Chronic hepatitis c is one of the liver diseases that show hepatic iron accumulation. |
| PubMedID- 24470860 | hepatitis b can lead to liver diseases ranging from the acute hepatitis to chronic hepatitis, cirrhosis and hepatocellular carcinoma (hcc) (1-2). |
| PubMedID- 22989301 | Background and aim: non-alcoholic fatty liver disease (nafld) overlapping with chronic hepatitis b virus (hbv) infection is undergoing a rapid increase in china. |
| PubMedID- 23707779 | Dietary cholesterol intake is associated with progression of liver disease in patients with chronic hepatitis c: analysis of the hepatitis c antiviral long-term treatment against cirrhosis trial. |
| PubMedID- 20130783 | She had no risk factors for viral hepatitis, no family history of liver disease, and denied any alcohol consumption. |
| PubMedID- 25323125 | Patients with severe acute alcoholic hepatitis, a distinct subset of alcoholic liver disease have a potential for mortality in about 25% within about 1 month despite treatment with available specific agents such as corticosteroids and/or pentoxifylline. |
| PubMedID- 25131040 | The population had an average age of 57.5 years, predominantly formed by men (82.5%), with an average imc of 26.7, meld of 13, with viral hepatitis as main cause of liver disease. |
| PubMedID- 23546360 | In patients whom the liver is the most impaired organ, the liver disease can present with recurrent hepatitis, cirrhosis, or liver failure. |
| PubMedID- 24695489 | End stage liver disease associated with hepatitis c virus infection constitutes one of the principal indications for liver transplant. |
| PubMedID- 23551989 | The association between circulating oestradiol levels and severity of liver disease in males with hepatitis b virus infection. |
| PubMedID- 24742346 | hepatitis a infection in patients with chronic viral liver disease: a cross-sectional study in jahrom, iran. |
| PubMedID- 21760995 | Autoimmune hepatitis is one of the few liver diseases with excellent response to therapy. |
| PubMedID- 21128862 | liver disease in patients with chronic hepatitis c virus (hcv) infection has an accelerated course in the presence of human immunodeficiency virus (hiv) coinfection. |
| PubMedID- 25379307 | Autoimmune hepatitis is one of the few liver diseases with excellent response to therapy; most patients with aih have a favorable response to treatment with prednisolone and azathioprine, although some patients with refractory aih or more aggressive disease require more potent immune-suppressant agents, such as cyclosporine [2]. |
| PubMedID- 26384610 | To determine the threshold value for identifying chronic liver disease, 29 patients with chronic hepatitis b who underwent liver biopsy, including patients without fibrosis (fibrosis stage f0; n = 9) and patients with substantial fibrosis (f1-f2; n = 20) were also investigated. |
| PubMedID- 23703797 | Vitamin d is an important immune modulator that plays an emerging role in inflammatory and metabolic liver diseases, including infection with hepatitis c virus (hcv). |
| PubMedID- 21167232 | Autoimmune hepatitis was one of the first liver diseases for which an effective treatment was developed and the benefit proven by randomized controlled trials. |
| PubMedID- 26058465 | Persistent hbv infection can promote liver disease, thereby leading to hepatitis and cirrhosis [29]. |
| PubMedID- 22030902 | Risk for future clinical outcomes is proportional to the severity of liver disease in patients with chronic hepatitis c virus (hcv). |
| PubMedID- 23509784 | Healthy individuals showed no risk factors for viral hepatitis, no history of liver disease, and normal liver function. |
| PubMedID- 22371770 | Most hccs are associated with chronic liver diseases resulting from hepatitis b or c viral infection, and the processes of chronic inflammation and fibrosis act as a stressful condition. |
| PubMedID- 22359532 | Nested case control studies have a distinct advantage from traditional case control studies because both cases and controls are chosen from the same, well-defined source population, in this study from the halt-c study population where all patients had chronic hepatitis c infection with chronic liver disease. |
| PubMedID- 24455227 | In addition, cytokine gene polymorphisms have been reported to be associated with liver disease severity in patients with viral hepatitis [10, 25] besides their impact on the cytokines production capacity [32–34]; therefore, heterogeneity of the candidate gene in hbv-infected patients serves as a probable biomarker for influence the disease phenotypes. |
| PubMedID- 23061403 | In high income settings, chronic liver disease – associated with hepatitis c and b virus, long term drug-induced toxicity, alcohol related and non-alcoholic fatty liver disease – has become a leading cause of chronic morbidity and mortality in people living with hiv [14]. |
| PubMedID- 22980664 | [expression of mcp-1 in the patients of chronic hepatitis b complicated with nonalcoholic fatty liver disease]. |
| PubMedID- 24155775 | Therefore, it is a major global health problem 1-5. most cases of hcc are attributable to chronic liver disease resulting from chronic hepatitis b virus (hbv) and hepatitis c virus (hcv) infection 1-5. a recent report by chung et al. |
| PubMedID- 24742271 | Most of these infections cause chronic hepatitis and leading to progressive liver disease including cirrhosis, fibrosis and finally hepatocellular carcinoma (hcc) [3-5]. |
| PubMedID- 23146778 | All articles that provided enough information to estimate the chronic liver disease risk associated with occult hepatitis b virus infection were selected. |
| PubMedID- 24403913 | Measured nine serum fibrosis markers including tissue inhibitor of metalloproteinase 1 (timp-1), tenascin-c, piiinp, laminin, matrix metalloproteinase-2 and 9, collagen type iv, collagen type vi and hyaluronan to predict advanced liver disease in patients with chronic hepatitis b. they observed that levels of timp1 and ha and finally their combination are powerful markers amongst other measured serum fibrosis markers to be used instead of a liver biopsy (10). |
| PubMedID- 25903706 | Objectives: to investigate the performance of real-time 2d shear wave elastography (rt 2d-swe) for non-invasive staging of liver disease in patients with chronic viral hepatitis (cvh). |
| PubMedID- 26174470 | hepatitis e virus in patients with decompensated chronic liver disease: a prospective uk/french study. |
| PubMedID- 26138651 | Background: rising rates of obesity, diabetes mellitus (dm), and nonalcoholic fatty liver disease among patients with chronic hepatitis c virus infection (hcv) may contribute to more rapid disease progression. |
| PubMedID- 25216239 | liver diseases were mostly attributed to hepatitis b virus infection (34%). |
| PubMedID- 20617177 | Chronic hepatitis c is associated with severe liver disease including hepatitis, liver cirrhosis and hepatocellular carcinoma and it is the most frequent indication for liver transplantation [4]. |
| PubMedID- 21415769 | Background: hepatitis b leads to chronic liver disease, cirrhosis, and hepatocellular cancer. |
| PubMedID- 24651854 | Importantly, similar m2-like macrophage accumulation was confirmed in chronic hepatitis b patients with liver diseases. |
| PubMedID- 23311684 | Problem drug users are at high risk of liver disease resulting from hepatitis c virus (hcv) infection because of its high prevalence in this population [7]. |
| PubMedID- 23451126 | Further, we excluded trials on vaccination for prevention of hepatitis b recurrence due to hbv-related liver disease, transplant recipients with a history of hbv infection or anti-hbc positive grafts. |
| PubMedID- 24658127 | However, our findings and those from spain [31] conflict with a recent finding from turkey of the existence of a correlation between serum hbsag levels and hdv viremia, regardless of histological staging and the grading of liver disease in patients with chronic hepatitis delta [11]. |
| PubMedID- 24130726 | This study analyses the evolution of liver disease in women with chronic hepatitis c during the third trimester of pregnancy and the post-partum period, as a natural model of immune modulation and reconstitution. |
| PubMedID- 23923056 | Therefore, the objectives of this study were: (1) to evaluate adherence to hepatitis vaccination guidelines in patients with chronic liver disease at a tertiary care hepatology clinic, (2) to identify barriers to vaccinations in patients with chronic liver disease, and (3) to determine physician variability in adherence to vaccination guidelines. |
| PubMedID- 19800334 | Background & aims: human immunodeficiency virus (hiv) infection accelerates liver disease progression in patients with hepatitis c virus (hcv) and could shorten survival of those awaiting liver transplants. |