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PedAM

Pediatric Disease Annotations & Medicines




Disease irritable bowel syndrome
Phenotype |constipation
Sentences 59
PubMedID- 23162373 Burden of constipation-predominant irritable bowel syndrome (ibs-c) in france, italy, and the united kingdom.
PubMedID- 22963061 Lubiprostone is effective for the treatment of constipation-predominant irritable bowel syndrome, and alosetron (restrictions for use apply in the united states) and tegaserod (available only for emergency use in the united states) are approved for patients with severe symptoms in whom conventional therapy has been ineffective.
PubMedID- 25781368 Introduction: the irritable bowel syndrome with constipation (ibs-c) and chronic idiopathic constipation (cic) are associated with substantial symptom and disease burden.
PubMedID- 26533548 The burden of moderate-to-severe irritable bowel syndrome with constipation (ibs-c) in france: a comparison with the european results from the ibis-c observational study.
PubMedID- 24812563 The study of ardatskaia on 30 patients having irritable bowel syndrome with predominance of constipation showed that normoflorin therapy had normalized the intestinal motor activity through changes in microbial flora of the intestines [12].
PubMedID- 22830234 Objective: to evaluate the clinical effectiveness of biocomplexes "normoflorin l, b" in the treatment of functional bowel disease with constipation syndrome.
PubMedID- 22847198 Material/methods: thirty patients with a diagnosis of constipation-predominant irritable bowel syndrome and 30 healthy volunteers were included in the study.
PubMedID- 25653859 Background: optimal clinical trial endpoints for irritable bowel syndrome with constipation (ibs-c) are uncertain.
PubMedID- 20200325 Objectives: tegaserod, a partial 5-ht(4) agonist previously approved for treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation, was suspended from us marketing in 2007, based on pooled clinical trial results which contained a signal suggesting increased risk of cardiovascular ischemic events (cvies).

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