PedAM
Pediatric Disease Annotations & Medicines
| Disease | hypoglycemia |
| Phenotype | |type 2 diabetes |
| Sentences | 135 |
| PubMedID- 22748821 | Background: addition of a sulphonylurea to metformin improves glycaemic control in type 2 diabetes, but is associated with hypoglycaemia and weight gain. |
| PubMedID- 24909093 | Effect of exogenously administered glucagon versus spontaneous endogenous counter-regulation on glycaemic recovery from insulin-induced hypoglycaemia in patients with type 2 diabetes treated with a novel glucokinase activator, azd1656, and metformin. |
| PubMedID- 24432042 | Optimizing glycemic control and minimizing the risk of hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 24030920 | The incidence of mild and severe hypoglycaemia in patients with type 2 diabetes mellitus treated with sulfonylureas: a systematic review and meta-analysis. |
| PubMedID- 20236369 | A common cause of hypoglycaemia in people with type 2 diabetes is glucose-lowering medication, in particular, those which raise insulin independently of ambient glucose concentration such as sulphonylureas and exogenous insulin. |
| PubMedID- 26026367 | Glycemic control paradox: poor glycemic control associated with higher one-year and eight-year risks of all-cause hospitalization but lower one-year risk of hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 26370882 | Background: to investigate whether a history of prior cardiovascular disease (cvd) is associated with severe hypoglycemia (sh) in patients with type 2 diabetes. |
| PubMedID- 22280196 | Economic burden of hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 20811029 | Due to its glucose-dependent mechanism of action, saxagliptin as monotherapy or in combination with metformin results in a low risk for hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 24204343 | Indeed, poor cognitive function also increases the risk of severe hypoglycemia in patients with type 2 diabetes (punthakee et al., 2012). |
| PubMedID- 22127800 | Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 26417415 | Thus, further studies are required regarding fear of hypoglycemia in patients with type 2 diabetes mellitus. |
| PubMedID- 25928628 | The current study demonstrates that even asymptomatic mild hypoglycemia in type 2 diabetes patients with high cv risk is associated with unfavorably altered plasma fibrin clot structure and lysability. |
| PubMedID- 22738801 | hypoglycemia in patients with type 2 diabetes from india and malaysia treated with sitagliptin or a sulfonylurea during ramadan: a randomized, pragmatic study. |
| PubMedID- 21561372 | The contribution of glucose variability to asymptomatic hypoglycemia in persons with type 2 diabetes. |
| PubMedID- 21951832 | The act of fasting and treatment with certain antihyperglycaemic agents increase the risk of hypoglycaemia in patients with type 2 diabetes. |
| PubMedID- 24089545 | Association between excessive daytime sleepiness and severe hypoglycemia in people with type 2 diabetes: the edinburgh type 2 diabetes study. |
| PubMedID- 26261902 | Using participants from the action to control cardiovascular risk in diabetes (accord) study, we hypothesized that insulin deficiency and islet autoantibodies in patients with clinically diagnosed type 2 diabetes would be associated with severe hypoglycaemia and death. |
| PubMedID- 23748506 | Background and aim: exenatide is a glucagon-like peptide-1 receptor agonist demonstrated to improve glycemic control with low hypoglycemia risk in patients with type 2 diabetes mellitus. |
| PubMedID- 25112609 | Aim: to review and discuss the results from the clinical controlled trials comparing a dipeptidyl peptidase-4 inhibitor with placebo treatment as add-on to insulin treatment with respect to changes in hba1c , weight, fasting plasma glucose, risk of hypoglycaemia and safety in patients with type 2 diabetes. |
| PubMedID- 22212499 | We investigated total mortality, cardiovascular and microvascular events, and hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 23101951 | Background: we set out to study the relationship between different measures of glycemic variability and the rate of hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 25806359 | Methods: we describe a case with type 2 diabetes who complained of episodes of recurrent hypoglycaemia in last few weeks. |
| PubMedID- 23425012 | Dapagliflozin added to metformin for 102 weeks enabled sustained reductions in hba1c, fpg, and weight without increased risk of hypoglycemia in patients with type 2 diabetes who were inadequately controlled on metformin alone. |
| PubMedID- 22449098 | Conclusion: this single-arm study suggested that switching to insulin glargine plus oads significantly improved glycaemic control, with a low incidence of hypoglycaemia, in patients with type 2 diabetes uncontrolled on premixed insulin plus oads. |
| PubMedID- 22937294 | Insulin in the medical management of postprandial hypoglycemia in a patient with type 2 diabetes after gastric bypass surgery. |
| PubMedID- 22371733 | The most frequent causes of hypoglycaemia in patients with type 2 diabetes treated with oral hypoglycaemic agents are: dose not adjusted for meals and physical activity, renal and/or hepatic dysfunction, administration of certain drugs (β-blockers, ace inhibitors, sulphonamides) and alcohol consumption. |
| PubMedID- 21199269 | Aim: the objective of this systematic review and meta-analysis was to assess the effect of pramlintide on glycemic control, weight and incidence of nausea and hypoglycaemia in patients with type 2 diabetes mellitus (t2dm) and in obese patients without diabetes (obp). |
| PubMedID- 26061690 | hypoglycaemia in type 2 diabetes is associated with a considerable cost and burden to the health service, with an estimated annual cost to the nhs of £39 million[1]. |
| PubMedID- 25004305 | Factitious hypoglycemia in pregnancy in a patient with type 2 diabetes. |
| PubMedID- 23859434 | Real-world rates, predictors, and associated costs of hypoglycemia among patients with type 2 diabetes mellitus treated with insulin glargine: results of a pooled analysis of six retrospective observational studies. |
| PubMedID- 20664017 | Conclusions: access to a computer insulin order template was associated with improved mean glucose levels without increasing hypoglycemia in patients with type 2 diabetes. |
| PubMedID- 21112027 | Little is known about the frequency of and responses to nocturnal hypoglycaemia in patients with type 2 diabetes. |
| PubMedID- 21195501 | Self-reported experience of hypoglycemia among adults with type 2 diabetes mellitus (exhype). |
| PubMedID- 20061360 | Estimates of the incidence of severe hypoglycaemia in patients with type 2 diabetes vary, depending on definitions and methods of ascertainment. |
| PubMedID- 23256228 Systematic Review of the Evidence | We conducted the current review to provide broader insight into the incidence of, the risk factors for, and the clinical and social impact of severe hypoglycemia in adults with type 2 diabetes treated with glucose lowering medications. |
| PubMedID- 24855344 | Impact of hypoglycemia on patients with type 2 diabetes mellitus and their quality of life, work productivity, and medication adherence. |
| PubMedID- 24843771 | Dapagliflozin added to metformin for 102 weeks resulted in sustained reductions in hba1c, fasting blood glucose and weight without increased risk of hypoglycemia in patients with type 2 diabetes inadequately controlled by metformin alone47. |
| PubMedID- 25325279 | Optimal candidates for the switch from glimepiride to sitagliptin to reduce hypoglycemia in patients with type 2 diabetes mellitus. |
| PubMedID- 24757202 | Risk of cardiac arrhythmias during hypoglycemia in patients with type 2 diabetes and cardiovascular risk. |
| PubMedID- 26321136 | Increased secretion of glp-1 may have caused reactive hypoglycaemia in patients with type 2 diabetes undergoing gastric surgery. |
| PubMedID- 23589542 | Severe hypoglycemia in patients with type 2 diabetes has been shown to occur at rates of 35 (24) to 70 (23) per 100 patient-years. |
| PubMedID- 23150950 | Impact of self-treated hypoglycaemia in type 2 diabetes: a multinational survey in patients and physicians. |
| PubMedID- 25647516 | This study describes demographic characteristics, comorbidities, and hypoglycemia events in patients with type 2 diabetes mellitus (t2dm) identified using 2011 medicare 5% standard analytical files. |
| PubMedID- 23529773 | Emergency hospitalizations for severe hypoglycaemia in patients with type 2 diabetes. |
| PubMedID- 23952328 | Increasing awareness of hypoglycaemia in patients with type 2 diabetes treated with oral agents. |
| PubMedID- 26254702 | The primary objective of this 9-week study was to determine the frequency of hypoglycemia in patients with stable insulin-treated type 2 diabetes mellitus by comparing self-monitored blood glucose (smbg) measurement with continuous glucose monitoring (cgm). |
| PubMedID- 22179956 | These observations suggest that the glycemic target may modify the relationship between mortality and severe hypoglycemia in patients with type 2 diabetes, particularly in patients who experience frequent hypoglycemia. |
| PubMedID- 22517736 | hypoglycemia in type 2 diabetes was long thought to be a trivial issue, as it occurs less commonly than in type 1 diabetes. |
| PubMedID- 25909295 | The association of renal disease with hypoglycemia in patients with type 2 diabetes is also linked to an increased risk of cardiovascular events [46]. |