PedAM
Pediatric Disease Annotations & Medicines
| Disease | heart disease |
| Phenotype | |hypertension |
| Sentences | 247 |
| PubMedID- 23703252 | Recent analyses have shown that there is no convincing evidence for the use of beta-blockers as first-line therapy in hypertension or in patients with stable coronary heart disease. |
| PubMedID- 23069841 | Adjustment variables included age, sex, bmi, hypertension status, history of coronary heart disease, total cholesterol, educational attainment, income level, and smoking status. |
| PubMedID- 21943933 | Efficacy and safety of bosentan for pulmonary arterial hypertension in adults with congenital heart disease. |
| PubMedID- 26299611 | Pulmonary hypertension due to left heart disease: the prognostic implications of diastolic pulmonary vascular pressure gradient. |
| PubMedID- 26504732 | The treatment of choice for pulmonary hypertension due to left heart disease (group 2), due to lung disease (group 3) or due to unclear multifactorial mechanisms (group 5) is the state-of-the-art therapy of the underlying disease. |
| PubMedID- 24075485 | Background: pulmonary hypertension associated with congenital heart disease increases the risk of surgery using cardiopulmonary bypass. |
| PubMedID- 22783203 | #adjusted for age (70–74, 75–79, 80–84, and 85+ years), sex, body mass index, hypertension, hypercholesterolemia, diabetes, history of coronary heart disease, history of stroke, history of renal disease, history of hepatic disease, drinking status, smoking status, physical activity, physical performance, depressive symptoms, mini-mental state examination, and use of tranquilizers. |
| PubMedID- 22884380 | Pulmonary hypertension associated with left heart disease is the most common form of pulmonary hypertension encountered in clinical practice today. |
| PubMedID- 21723630 | Pulmonary arterial hypertension (pah) associated with congenital heart disease (chd) due to systemic to pulmonary shunting is associated with a high risk of morbidity and mortality. |
| PubMedID- 26046840 | Methods: in a prospective cohort of patients with right heart catheterization, we identified 73 adult patients who had pulmonary hypertension due to left heart disease (ph-lhd) associated with hfpef (left ventricular ejection fraction >/=50% by echocardiography); hemodynamically defined as a mean pulmonary artery pressure >/=25 mm hg and pulmonary artery wedge pressure >15 mm hg. |
| PubMedID- 25620261 | [management of pulmonary arterial hypertension associated with congenital heart disease with specific pulmonary arterial hypertension vasoactive drugs combined with transcatheter closure strategy:a case report]. |
| PubMedID- 25904000 | Risk factors such as age, hypertension, previous history of heart diseases and diabetes influence the evolution of pulse wave velocity before dialysis initiation whereas their impact during the course of dialysis has not yet been demonstrated [17]. |
| PubMedID- 22682107 | Metabolic syndrome (mets), a cluster of cardiovascular risk factors characterized by insulin resistance, abdominal obesity, dyslipidemia and hypertension, is associated with coronary heart disease, leading to increased cardiovascular and total mortality [14,15]. |
| PubMedID- 24629043 | Apah-chd: pulmonary arterial hypertension associated with congenital heart disease; apah-ctd: pulmonary arterial hypertension associated with connective tissue disease; ci: confidence interval; hr: hazard ratio; mpap: mean pulmonary arterial pressure; nyha: new york heart association; pah: pulmonary arterial hypertension; pcwp: pulmonary capillary wedge pressure; rhc: right heart catheterization; sd: standard deviation; 6mwd: 6-minute walk distance. |
| PubMedID- 26261613 | Objective: to investigate the relationship between p-selectin gene polymorphism and congenital heart disease (chd) with pulmonary hypertension (pah). |
| PubMedID- 22068906 | Plasma von willebrand factor as a predictor of survival in pulmonary arterial hypertension associated with congenital heart disease. |
| PubMedID- 25089008 | Left heart disease: a frequent cause of early pulmonary hypertension in systemic sclerosis, unrelated to elevated nt-probnp levels or overt cardiac fibrosis but associated with increased levels of mr-proanp and mr-proadm: retrospective analysis of a french canadian cohort. |
| PubMedID- 26203294 | Chronic left heart diseases with secondary pulmonary hypertension (group 2 of pulmonary hypertension classification10). |
| PubMedID- 22693502 | Type 1 diabetes mellitus, hypertension, history of ischemic heart disease, renal impairment (serum creatinine >150 umol/l), and valvular heart diseases were excluded. |
| PubMedID- 25911012 | Decrease in quality of life predicts mortality in adult patients with pulmonary arterial hypertension due to congenital heart disease. |
| PubMedID- 23098893 | We investigated the occurrence of bmpr2 mutation and genetic polymorphisms in children with pulmonary hypertension associated with congenital heart disease (aph/chd) and correlated with the pulmonary haemodynamic and vasoreactivity. |
| PubMedID- 26537355 | hypertension, a precursor of hypertensive heart disease, is present in up to 46 % nigerian adult population, and in an increasing percentage of nigerian adolescents [4, 5]. |
| PubMedID- 23056110 | The experience of angina pain, heart attack, palpitation, and heart disease in patients with hypertension especially smokers and passive smokers was more than that of healthy subjects (table 3). |
| PubMedID- 26202179 | Comparative effectiveness of sildenafil for pulmonary hypertension due to left heart disease with hfref. |
| PubMedID- 26528452 | (15) demonstrated that pulmonary arterial capacitance is correlated with functional capacity and survival in children with idiopathic pulmonary arterial hypertension and pah associated with congenital heart disease. |
| PubMedID- 25840093 | Pathophysiology and clinical relevance of pulmonary remodelling in pulmonary hypertension due to left heart diseases. |
| PubMedID- 23548773 | We explored the hypothesis that the level of ace2 protein contents may be decreased in patients with pulmonary arterial hypertension (pah) due to congenital heart disease (chd). |
| PubMedID- 23041100 | Efficacy of exercise training in pulmonary arterial hypertension associated with congenital heart disease. |
| PubMedID- 26286137 | Persistent hypertension increases the risk of developing coronary heart disease, stroke and other cardiovascular diseases (cvds), such as heart failure [4]. |
| PubMedID- 23158820 | Conclusion: there was the expression of urotensin ii protein and mrna in the lung of pulmonary hypertension patients with congenital heart disease, and these expression may involve the formation of pulmonary hypertension of congenital heart disease. |
| PubMedID- 21679007 | A reduction in the release of sympathomimetic substances by β-blockers has been demonstrated to play a role in the primary and secondary prevention of cardiovascular events through several mechanisms,[23,24] especially for hypertension complicated with ischemic heart disease. |
| PubMedID- 25478504 | Precisely, hypertension can lead to ischemic heart disease (myocardial infarction), heart failure, stroke, dementia and chronic kidney disease (2). |
| PubMedID- 23906950 | Group 2 comprises pulmonary hypertension owing to left heart disease; group 3, pulmonary hypertension owing to lung diseases and/or hypoxia; group 4, chronic thromboembolic pulmonary hypertension; and group 5, pulmonary hypertension of unknown cause. |
| PubMedID- 24029867 | Using multiple linear regression models, we compared mean crp levels among the groups after adjusting for age, race, education, smoking, hypertension, personal history of coronary heart disease (chd) or stroke, diabetes, dyslipidemia, statins, hormone replacement therapy, and family history of chd or stroke. |
| PubMedID- 21556451 | There was a statistically significant difference between the two groups for smoking, hyperlipidaemia, hypertension and family history of coronary heart disease (table 1). |
| PubMedID- 23653531 | Patients having systemic hypertension, diabetes mellitus, history of ischemic heart disease, significant valvular heart disease, chronic obstructive pulmonary disease, hypo- or hyperthyroidism, renal failure or any associated systemic disease were excluded. |
| PubMedID- 24267300 | Pulmonary arterial hypertension associated with congenital heart disease. |
| PubMedID- 22526220 | Elevated homocysteine and asymmetric dimethyl arginine levels in pulmonary hypertension associated with congenital heart disease. |
| PubMedID- 23052666 | This study enrolled 29 congenital heart disease cases with pulmonary arterial hypertension and 40 healthy subjects followed at our center. |
| PubMedID- 23236330 | Eisenmenger syndrome is the clinical phenotype of an extreme form of pulmonary arterial hypertension associated with congenital heart disease. |
| PubMedID- 23918108 | World health organization (who) group 2 pulmonary hypertension (ph) due to left-side heart disease (ie, heart failure or left-sided valvular heart disease) is the most common form of ph in western countries. |
| PubMedID- 26413109 | Background and objectives: despite remarkable advances in pediatric cardiology, pulmonary arterial hypertension associated with congenital heart disease remains a major problem. |
| PubMedID- 23932041 | Objectives: the two hemodynamic profiles in left heart disease (lhd) with pulmonary hypertension (ph), passive ph with increased pulmonary venous pressure and reactive ph with increased pulmonary vascular resistance (pvr > 3 wood units, wu), are difficult to distinguish non-invasively. |
| PubMedID- 25924799 | The classification differentiates pulmonary arterial hypertension (pah), ph due to left heart disease, ph in lung diseases and/or hypoxia, chronic thromboembolic pulmonary hypertension (cteph), and ph with unclear/multifactorial mechanisms. |
| PubMedID- 25737007 | This study investigated the clinical value of plasma asymmetrical dimethyl-l-arginine (adma) level in the diagnosis, staging, and treatment response in congenital heart disease (chd) patients with pulmonary arterial hypertension (pah). |
| PubMedID- 23640439 | Accuracy of doppler echocardiography in the assessment of pulmonary arterial hypertension in patients with congenital heart disease. |
| PubMedID- 25721948 | Introduction: pulmonary hypertension (ph) due to left-sided heart disease (group 2 ph) is most commonly due to passive backward transmission of elevated left-sided heart pressures. |
| PubMedID- 24225339 | Assessment of operability of patients with pulmonary arterial hypertension associated with congenital heart disease. |
| PubMedID- 21069290 | Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease. |
| PubMedID- 23576900 | Although the age, duration of af, left atrial size, incidence of hypertension, and proportion with underlying heart disease were significantly higher in the dm patients compared with the non-dm patients, the rate of recurrence of af after first-time ablation was similar in the two groups (32.3% versus 22.4%, p = 0.24). |