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PedAM

Pediatric Disease Annotations & Medicines




Disease diabetes mellitus, insulin-dependent
Phenotype |hypoglycemia
Sentences 108
PubMedID- 23514728 Large pre- and postexercise rapid-acting insulin reductions preserve glycemia and prevent early- but not late-onset hypoglycemia in patients with type 1 diabetes.
PubMedID- 21246006 For this reason, the american association of clinical endocrinologists has recommended the use of personal devices for glucose control and prevention of hypoglycemia in patients with type 1 diabetes [2,3] and pregnancy with diabetes [4,5].
PubMedID- 19808914 The absence of a peak with the use of these insulin analogs has led to decreased incidence of symptomatic, overall, and nocturnal hypoglycemia in patients with type 1 diabetes (3).
PubMedID- 20518101 Diabetes: nocturnal hypoglycemia is frequent in patients with type 1 diabetes mellitus.
PubMedID- 24321724 It is relatively well known that moderate-intensity aerobic exercise increases the risk of hypoglycemia in individuals with type 1 diabetes.
PubMedID- 22316089 Background: the efficacy of automatic suspension of insulin delivery in induced hypoglycemia among subjects with type 1 diabetes was evaluated.
PubMedID- 22563248 The uk study group found that the incidence of severe hypoglycemia in patients with type 1 diabetes treated with insulin for >15 years was three times higher than in those treated for <5 years.
PubMedID- 23497433 However this intensive diabetes treatment could be associated with an increased risk of hypoglycemia [5], particularly in patients with type 1 diabetes mellitus and patients with longstanding insulin-treated type 2 diabetes mellitus [6-9].
PubMedID- 26046236 Changes in hba1c, insulin dose and incidence of hypoglycemia in patients with type 1 diabetes after switching to insulin degludec in an outpatient setting: an observational study.
PubMedID- 23173147 In the article, incidence of severe hypoglycemia in patients with type 1 diabetes was 11.5 in the first period and 23.4 episodes/100,000 person-years in the second period.
PubMedID- 26207053 Interventions that restore awareness of hypoglycemia in adults with type 1 diabetes: a systematic review and meta-analysis.
PubMedID- 24589650 Objectives: the aim of this study was to investigate specific fears related to hypoglycemia in adults with type 1 diabetes and to investigate how aspects of fear of hypoglycemia may differ between genders.
PubMedID- 26163815 We have found evidence of microstructural changes in white matter regions, reduced gray matter density, and reduced activation of the thalamus in response to recurrent hypoglycemia in patients with type 1 diabetes.
PubMedID- 21355723 In this pilot study, we determined the effect of optimized insulin therapy on weight gain and frequency of hypoglycemia in patients with long-standing type 1 diabetes mellitus.
PubMedID- 25922810 Therefore, diabetic education per se is an effective tool for the treatment of hypoglycemia in patients with type 1 diabetes.
PubMedID- 25053587 We studied the effects of gip and glp-1 on glucagon responses to insulin-induced hypoglycemia in patients with type 1 diabetes mellitus (t1dm).
PubMedID- 24804697 A randomized trial of a home system to reduce nocturnal hypoglycemia in type 1 diabetes.
PubMedID- 25556593 Insulin-induced hypoglycemia in a patient with insulin-dependent diabetes mellitus resulted in chronic pontine dysfunction [10], confirming the unique vulnerability of the pons to hypoglycemia.
PubMedID- 23900589 Compelling evidence for this comes from the diabetes control and complications trial (dcct), which reported an inverse relationship between hba1c levels and the occurrence of severe hypoglycemia in participants with type 1 diabetes (4).
PubMedID- 23537420 Nocturnal continuous glucose monitoring: accuracy and reliability of hypoglycemia detection in patients with type 1 diabetes at high risk of severe hypoglycemia.
PubMedID- 22892724 Here, we tested the hypothesis that this region is less activated during hypoglycemia in subjects with type 1 diabetes (t1dm) and hypoglycemia unawareness relative to controls.
PubMedID- 26345338 Naltrexone for treatment of impaired awareness of hypoglycemia in type 1 diabetes: a randomized clinical trial.
PubMedID- 23992543 Objective: to determine the glucagon and epinephrine responses to insulin-induced hypoglycemia in adolescents with recent-onset type 1 diabetes mellitus (t1dm).
PubMedID- 26068866 Conclusions: in a large cohort with a 5-year follow-up and in a multicenter network setting, islet transplantation was safe and efficient in restoring good and lasting glycemic control and preventing severe hypoglycemia in patients with type 1 diabetes.
PubMedID- 21443586 Objective: to determine the most effective of four oral treatments for hypoglycemia in children with type 1 diabetes using a weight-based protocol during diabetes camp.
PubMedID- 21747831 Recently, it was demonstrated that during spontaneous hypoglycemia in patients with type 1 diabetes, qtc interval can be moderately increased [44], whereas glucose-qtc association is reported to differ among individuals with type 1 diabetes.
PubMedID- 20876723 hypoglycemia in type 1 diabetes.
PubMedID- 24103902 A retrospective case-note audit was carried out in adult type 1 diabetes patients with ongoing problematic hypoglycemia leading to limitation in daily activities and iah (gold score [a likert linear analog scale in which patients are asked to score between 1 and 7, respectively, if they are always aware or never aware of the onset of hypoglycemia] >4) (4) despite structured education with or without continuous subcutaneous insulin infusion (csii), who then used cgm in addition to csii or multiple daily injection (mdi) for at least 12 months.
PubMedID- 22071283 The main goal of closed-loop therapy is to achieve good glycemic control while reducing the risk of hypoglycemia in people with type 1 diabetes.
PubMedID- 25024710 Effects of fiber supplementation on glycemic excursions and incidence of hypoglycemia in children with type 1 diabetes.
PubMedID- 20723825 hypoglycemia in type 1 diabetes mellitus.
PubMedID- 22111165 [recurrent hypoglycemia in a patient with type 1 diabetes.
PubMedID- 23630300 All transplant recipients had long-standing c-peptide–negative type 1 diabetes complicated by hypoglycemia unawareness and frequent severe hypoglycemia events.
PubMedID- 24122616 The performance of the proposed r-bbnn algorithm was evaluated by an application to the field of medical diagnosis using real hypoglycemia episodes in patients with type 1 diabetes mellitus.
PubMedID- 22723582 Allogeneic islet transplantation offers a minimally invasive option for β-cell replacement in people with type 1 diabetes complicated by recurrent severe hypoglycemia and/or marked glycemic lability.
PubMedID- 24130355 Restoration of self-awareness of hypoglycemia in adults with long-standing type 1 diabetes: hyperinsulinemic-hypoglycemic clamp substudy results from the hypocompass trial.
PubMedID- 21266651 Factors predictive of severe hypoglycemia in type 1 diabetes: analysis from the juvenile diabetes research foundation continuous glucose monitoring randomized control trial dataset.
PubMedID- 25986629 We investigated known and potential risk factors for hypoglycemia in subjects with type 1 diabetes.
PubMedID- 23692715 Neurocognitive functions were negatively affected by early onset of diagnosis, poor glycemic control and frequent hypoglycemia in children with type i diabetes mellitus.
PubMedID- 21411513 Conclusions: these data suggest that increased vmh gabaergic inhibition is an important contributor to the absent glucagon response to hypoglycemia and the development of counterregulatory failure in type 1 diabetes.
PubMedID- 23801814 A case of type 1 diabetes with nocturnal hypoglycemia after desensitization therapy for insulin allergy.
PubMedID- 26354059 Recently, one study reported alterations of all electrolytes during insulin induced hypoglycemia in patients with type 1 diabetes.
PubMedID- 23855268 Caffeine intake has also been proposed to increase symptomatic warning signs of hypoglycemia in patients with type 1 diabetes and elevate blood glucose levels in patients with type 2 diabetes.
PubMedID- 23926399 In type 1 diabetes,especially with recurrent hypoglycemia, the action of icrhs in response to hypoglycemicstimulation is decreased (2, 3).
PubMedID- 24876539 This study incorporates physical activity measurements from a combined accelerometer/heart rate monitor (hrm) to improve the performance of an existing plgs algorithm at mitigating exercise-associated hypoglycemia in participants with type 1 diabetes.
PubMedID- 23882056 Statistically, the incidence of mild hypoglycemia in patients with type 1 diabetes is ~30 episodes/patient/year, whereas the incidence of severe hypoglycemia (i.e., requiring third-party assistance) may be as high as 3.2 episodes/patient/year (4).
PubMedID- 23920511 An information and communication technology system to detect hypoglycemia in people with type 1 diabetes.
PubMedID- 21984582 Specifically, we found that for patients with type 1 diabetes during hypoglycemia, wmt-related activation responses were increased in several cortical regions, including the parietal and frontal cortices, hippocampus, and cerebellum.
PubMedID- 21553500 Treatment of juvenile diabetes is still complicated by fear of hypoglycemia, fluctuating blood glucose levels and feeling of being different.
PubMedID- 23543638 An estimated 2–4% of deaths of people with type 1 diabetes have been attributed to hypoglycemia (cryer, 2004), and hypoglycemia also occurs in type 2 diabetes with prevalence rates of 70–80% in clinical trials of insulin (ukpds, 1998; jensen et al., 2010).

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