PedAM
Pediatric Disease Annotations & Medicines
| Disease | diabetes mellitus, insulin-dependent |
| Phenotype | |diabetes |
| Sentences | 82 |
| PubMedID- 24944918 | In addition, investigators in the diabetes prevention trial of type 1 diabetes (dpt-1) have detected a group of subjects with type 1 diabetes who are asymptomatic, have normal (<6.1 mmol/l) or impaired fasting glucose (6.1-<7.0 mmol/l), but have 2-h glucose values >11.1 mmol/l on their oral glucose tolerance tests (ogtt). |
| PubMedID- 19679645 | Type ii diabetes, non-insulin-dependent diabetes mellitus is becoming increasingly prevalent in many countries and affects 90% of diabetic patients. |
| PubMedID- 21270193 | The known diabetes-associated autoantibodies (daas) associated with type 1 diabetes include cytoplasmic islet cell (ica), insulin (iaa, microiaa [miaa]), 65-kda isoform of glutamic acid decarboxylase (gad-65, gada, gaa), and insulinoma-associated protein 2 (ia-2, ia-2a, ica512). |
| PubMedID- 20299479 | Nonetheless, these data support the concept that retinal microvascular geometric changes might represent a novel marker indicative of early diabetes-related microvascular injury in patients with type 1 diabetes. |
| PubMedID- 22923999 | Subjects currently under treatment for diabetes, diagnosed with type 1 diabetes mellitus, with any other systemic diseases, or with tobacco or alcohol habits were excluded from the study. |
| PubMedID- 20039825 | In order to investigate the immunosuppressive action of transforming growth factor-beta1 (tgf-beta1) in type 1 diabetes, 388 patients with type 1 diabetes and 229 normal controls were genotyped for the tgf-beta1 t (29) c gene polymorphism. |
| PubMedID- 20653753 | In 2007, diabetes-treatment-specific prescribing represented 57% of prescribing costs in type 1 diabetes and 28% in type 2 diabetes. |
| PubMedID- 21961697 | While physical activity and weight loss can prevent or delay type 2 diabetes, no way of preventing type 1 diabetes is known. |
| PubMedID- 22360870 | Number and sex ratio of children and impact of parental diabetes in individuals with type 1 diabetes. |
| PubMedID- 24078058 | Although insulin resistance is not part of the disease as in type 2 diabetes, patients with type 1 diabetes can develop an increasing requirement for insulin [4]. |
| PubMedID- 24026548 | All patients (10 females, mean 43.9 ± 9.5 years of age) had a verified diabetes diagnosis (12 with type 1 diabetes and 3 with type 2 diabetes), with an average disease duration of 24.3 ± 9.8 years. |
| PubMedID- 23479996 | Conclusion: the performed trials have indicated that it is expedient to use the vmc alfavit diabetes in adolescents with type 1 diabetes mellitus and dpnp. |
| PubMedID- 20045460 | Treatment with autologous bone marrow transplantation (abmt) can change the natural history of diabetes in patients with new-onset type 1 diabetes (t1d). |
| PubMedID- 22748110 | Type 2 diabetes (non-insulin-dependent diabetes) is an important risk factor in atherosclerotic cardiovascular disease[14,15]. |
| PubMedID- 26001397 | Reactivity to n-terminally truncated gad65(96-585) identifies gad autoantibodies that are more closely associated with diabetes progression in relatives of patients with type 1 diabetes. |
| PubMedID- 24344937 | Methods: patients who underwent tp were matched for age, sex and duration of diabetes with patients with type 1 diabetes. |
| PubMedID- 24645790 | The β-cell destruction is believed to be mediated through the actions of cd4 and cd8 t lymphocytes, b lymphocytes, macrophages, and dendritic cells 1. pancreas transplantation is a way to reverse diabetes in patients with insulin-dependent diabetes. |
| PubMedID- 25583696 | diabetes: elevated risk of mortality in type 1 diabetes mellitus. |
| PubMedID- 24088368 | iddm, insulin-dependent diabetes mellitus; nice-sugar, normoglycemia in intensive care evaluation and surviving using glucose algorithm regulation. |
| PubMedID- 25870585 | Marrow fat is higher with diabetes in rodent models of type 1 diabetes (54), but there have been few clinical studies of this relationship and results are inconsistent. |
| PubMedID- 24158996 | It has taken some 40 years of research to appreciate that juvenile diabetes, insulin-dependent diabetes, t1d, and latent autoimmune diabetes in the adult are the same thing. |
| PubMedID- 24847201 | Recently we demonstrated impaired sympathetic neurovascular transmission in plantar metatarsal arteries (pmas) from rats with streptozotocin (stz)-induced diabetes, a well-studied model of type i diabetes (johansen et al., 2013). |
| PubMedID- 22397700 | Although eligible patients had to be at least 30 years old and were identified using icd-10 codes for type 2 diabetes, some patients with type 1 diabetes may have been incorrectly indentified as having type 2 diabetes, although the number is likely to have been small. |
| PubMedID- 21617108 | The diabetes prevention trial of type 1 diabetes (dpt-1) study failed to show a protective effect of parenteral insulin (306). |
| PubMedID- 21372449 | Other types of diabetes, including type 1 diabetes and diabetes in pregnancy (defined by icd-10 codes e10 e12-14 and o24, respectively) were excluded from the analyses. |
| PubMedID- 25965806 | For subgroup analyses the whole esrd population with diabetes was divided in patients with type 1 diabetes or type 2 diabetes. |
| PubMedID- 22566893 | Mc depletion or inactivation can improve diet-induced type 2 diabetes and some forms of type 1 diabetes, but also can worsen other forms of type 1 diabetes, at least in experimental animals. |
| PubMedID- 24693454 | Recently it has been shown that in rats with streptozotocin- (stz-) induced diabetes, the classical model of diabetes type 1 [4, 5], remodeling of t-channels in the ntcn neurons, was pdn type specific with substantial differences in a case of the thermal hyperalgesia versus norm- or hypoalgesia [27]. |
| PubMedID- 22396204 | Having established that cml and diabetes-associated autoantibodies were predictive of type 1 diabetes, we then performed a twin study on a cohort of monozygotic (mz) and dizygotic (dz) pairs initially discordant for type 1 diabetes to investigate and control for potential confounding effects on these predictors of the disease itself (cotwin case-control design) and to determine the impact of genetic and environmental factors on them (classic twin design). |
| PubMedID- 23293534 | In multiple clinical trials, aceis or arbs slowed progression of diabetic and nondiabetic kidney disease between 16% and 56%.74–79 the landmark trial by the collaborative study group demonstrated the effectiveness of aceis in slowing progression of diabetes and ckd in patients with type 1 diabetes and macroalbuminuria, regardless of presence or absence of hypertension.77 in patients with type 2 diabetes and overt nephropathy, arbs were more effective than conventional therapy in the progression of nephropathy, despite similar blood pressure control.74,77,80 in patients with nondiabetic ckd, aceis slowed disease progression, and the benefits were greater in patients with higher levels of proteinuria.75,78,79,81 as evidenced by the african american study of kidney disease trial, setting blood pressure targets reduced proteinuria and slowed progression in african americans with hypertensive ckd.82 special attention and further research are needed to optimally manage hypertension in other at-risk and high-risk populations. |
| PubMedID- 21747831 | Among the factors significantly associated with cardiac autonomic dysfunction are central obesity, hypertension, smoking, hyperglycemia, dyslipidemia, and presence of microvascular complications, that is, retinopathy, nephropathy, and pubertal diabetes onset in patients with type 1 diabetes. |
| PubMedID- 23818528 | In a prior analysis, 564 individuals had c-peptide measurements by both the tosoh assay and the radioimmunoassay (rai) used in the diabetes prevention trial of type 1 diabetes (r = 0.961, tosoh = 0.96 × rai + 0.1). |
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