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PedAM

Pediatric Disease Annotations & Medicines




Disease colorectal cancer
Phenotype |liver metastasis
Sentences 105
PubMedID- 24277234 Conclusion: currently, the international arcad group supports the idea of developing recist for hrqol in pancreatic and colorectal cancer with liver metastasis, with a view to using hrqol as a co-primary endpoint along with a tumor parameter.
PubMedID- 20414778 The aim of the present study was to investigate differences in opn-positive tams between cases of colorectal cancer with synchronous liver metastasis and those without liver metastasis.
PubMedID- 24363829 We herein review past, present, and possible future markers of prognosis among colorectal cancer patients with liver metastasis undergoing resection with curative intent.
PubMedID- 22314329 Predictive factors for the benefit of perioperative folfox for resectable liver metastasis in colorectal cancer patients (eortc intergroup trial 40983).
PubMedID- 25611592 Perioperative tpo was analyzed prior to liver resection as well as on the first and fifth postoperative day in 46 colorectal cancer patients with liver metastasis (mcrc) as well as 23 hepatocellular carcinoma patients (hcc).
PubMedID- 22068817 Between november 2008 and october 2009, 63 colorectal cancer patients with unresectable liver metastasis were enrolled in this prospective study at the severance hospital, yonsei university health system, seoul, korea.
PubMedID- 24851215 [28] who used a mouse model, the results proved that liver metastasis of colorectal cancer might be caused by activation of α5β1-integrin.
PubMedID- 22131816 Similar results were obtained in a recent study involving 51 colorectal cancer patients with liver metastasis [73].
PubMedID- 24504141 Ccdc88a, also known as giv or girdin, codes for coiled-coil domain containing 88a, and was found to be more highly expressed in samples of colorectal cancers with liver metastasis compared to cancers without metastasis (60).
PubMedID- 21764578 Co-expression of stem cell genes cd133 and cd44 in colorectal cancers with early liver metastasis.
PubMedID- 23805353 The development of laparoscopic colorectal surgery and laparoscopic hepatectomy has made a minimally invasive surgical approach to treating colorectal cancer with liver metastasis feasible.
PubMedID- 21829768 In addition, in a study conducted on liver metastasis of colorectal cancer, zeng et al.
PubMedID- 26448934 Had clarified that strong expression of galectin-3 in colorectal cancer correlated with cancer progression, liver metastasis, and poor prognosis [13].
PubMedID- 21060790 Primary colorectal cancer with paired liver metastasis (n = 23): identification of recurrent chromosomal breakpoint regions for the 1p12, 8p12, 17p11.2 and 20p12.1 chromosome regions as defined by the affymetrix 500k snp array genotyping platform.
PubMedID- 24646558 Reply to letter: "predictive factors for the benefit of perioperative folfox for resectable liver metastasis in colorectal cancer patients (eortc intergroup trial 40983)".
PubMedID- 21207157 The purpose of this study was to investigate whether nuclear beta-catenin overexpression in colorectal cancer is associated with synchronous liver metastasis.
PubMedID- 22202333 The subject was 28 patients of colorectal cancer with synchronous unresectable liver metastasis who received mfolfox6 as a first-line treatment from 2005 to 2010.
PubMedID- 26557771 Reported that reg iv expression was associated with delayed liver metastasis of colorectal cancer [13], and inhibition of apoptosis by reg iv may participate in liver metastasis.
PubMedID- 26552809 Increased slex was reported in liver metastasis of colorectal cancer, and was associated with poor patient survival and early recurrence in colorectal carcinoma [27, 29].
PubMedID- 23302486 Objective: to investigate pik3ca, pten status in the primary lesion of colorectal cancer (crc): relationship with occurrences of liver metastasis and its prognosis.
PubMedID- 24358218 We first attempted to detect the liver metastasis of colorectal cancer generated by the isp injection of t-hct 116 cells.
PubMedID- 26404693 Objective: to investigate the prognostic factors of colorectal cancer patients with liver metastasis in order to provide reference for clinical practice.
PubMedID- 25458952 In the present study, we compared the microrna expression profiles between patients of colorectal cancer at diagnosis with and without liver metastasis.
PubMedID- 25866690 Designed a phase iii randomized clinical trial to define the role of y90 radioembolization in colorectal cancer with liver metastasis.
PubMedID- 22073198 In summary, we have developed a highly optimized mouse model for liver metastasis of colorectal cancer, which allows detection of the tumor load at the whole body level and enables an accurate timing of therapeutic interventions to target different stages of cancer progression and metastatic development.
PubMedID- 22084593 In endometrial cancer, ovarian cancer and high-grade osteosarcomas, respectively, ido expression correlates with poor overall survival.34–36 furthermore, our own group was able to show that ido had a significant prognostic value in terms of liver metastasis in patients with colorectal cancer.
PubMedID- 24448820 Cluster analysis (7 colorectal cancer patients with liver metastasis and 12 colorectal cancer patients without liver metastasis) indicated that mir-340 and mir-542-3p expressions were significantly decreased in epcam(+) bone marrow cells of patients with liver metastasis (p = 0.019 and 0.037, respectively).
PubMedID- 24444095 Hsa-mir-579 was a down-regulated mirna of ovarian cancer samples, and mir-579 is found to dysregulated in colorectal cancer with liver metastasis [21].
PubMedID- 22403747 In colorectal and breast cancer patients, an elevation in the serum il-2rα level indicates disease progression to stage iv or liver metastasis with colorectal cancer, and distant metastasis in breast cancer [8].
PubMedID- 23172529 Objective: to analyze the relationship of k-ras mutation with the development of liver metastasis in colorectal cancer patients and the survival outcomes.
PubMedID- 22871210 The above data indicate that the cd133+cxcr4+ subpopulation contributes to liver metastasis of colorectal cancer via emt.
PubMedID- 21174058 Of these, 4 mirnas including mir-150*, mir-125b-2*, mir-1179 and mir-139-3p were up-regulated in colorectal cancers with liver metastasis while the others were down-regulated.
PubMedID- 22437957 Totally laparoscopic strategies for the management of colorectal cancer with synchronous liver metastasis.
PubMedID- 26263637 colorectal cancer with synchronous liver metastasis (sm-crc) is extremely unfavorable prognostic factor.
PubMedID- 24550602 Survival rates for liver metastasis of colorectal cancer are comparable [35].
PubMedID- 26334293 Conclusions: sox plus cetuximab is safe and effective for advanced colorectal cancer with limited liver metastasis, and may lead to high liver resectability.
PubMedID- 25960808 Reported that vimentin methylation is characteristic for advanced colorectal cancers with liver metastasis and peritoneal dissemination.
PubMedID- 26218533 However, the sensitivity of pet/ct markedly decreased after chemotherapy and many colorectal cancer patients with liver metastasis underwent chemotherapy before or after surgery, hence pet/ct could not completely replace contrast enhanced ct or mr [25].
PubMedID- 23198045 A 40-year-old woman (height 157.8 cm, weight 46.8 kg) was scheduled for a laparoscopic low anterior resection (lar) and hepatic tumorectomy due to colorectal cancer with liver metastasis.
PubMedID- 24667486 Lymph node-independent liver metastasis in a model of metastatic colorectal cancer.
PubMedID- 22740990 Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis.
PubMedID- 21153819 Risk factors for the development of metachronous liver metastasis in colorectal cancer patients after curative resection.
PubMedID- 26316117 Downregulation of mir-138 as a contributing mechanism to lcn-2 overexpression in colorectal cancer with liver metastasis.
PubMedID- 20576588 [surgical treatment of liver metastasis in colorectal cancer with simultaneous liver resection].
PubMedID- 26092596 Expression of cancer stem cell markers in metastatic colorectal cancer correlates with liver metastasis, but not with metastasis to the central nervous system.
PubMedID- 24972738 Serum cd10 is associated with liver metastasis in colorectal cancer.
PubMedID- 22945388 Methodology: the study involved 55 patients of colorectal cancer with liver metastasis who underwent surgery at our department between february 1988 and april 2003.
PubMedID- 24972972 Aberrant s1pr1 expression in colorectal cancer was associated with metachronous liver metastasis and worse survival outcome, and also, it was an independent prognostic factor.
PubMedID- 26146543 The expression of mir-340 is significantly decreased in bone marrow cells of colorectal cancer patients with liver metastasis.
PubMedID- 24489916 20%–25% of colorectal cancer patients present with simultaneous liver metastasis at the time of diagnosis and a few patients are evaluated with primary tumor and liver metastasis resectable synchronously [1].

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