PedAM
Pediatric Disease Annotations & Medicines
| Disease | arteriosclerosis |
| Phenotype | |vascular disease |
| Sentences | 131 |
| PubMedID- 23476800 | Peripheral vascular disease due to underlying atherosclerosis affects the large- and medium-sized vessels, leading to poor arterial inflow with limb ischemia. |
| PubMedID- 21223581 | The paraoxonase (pon) genes have received major attention as antioxidants that attenuate oxidation of low density lipoprotein (ldl), a key regulator in the pathogenesis of atherosclerosis leading to several cardiovascular diseases [4]. |
| PubMedID- 24180493 | Another study has reported that carotid intima-media thickness (cimt), measured non-invasively with high-resolution ultrasound scanning, is a well-known indicator of generalized atherosclerosis and strongly associated with risk of cardiovascular disease [3]. |
| PubMedID- 26244503 | atherosclerosis, the leading cause of cardiovascular disease and mortality worldwide, is a chronic inflammatory disease characterized by the progressive formation of neo-intimal lesions and lumen narrowing of affected arteries. |
| PubMedID- 20920173 | Systemic lupus erythematosus (sle) is associated with an increased prevalence of cardiovascular disease (cvd), due to accelerated atherosclerosis [1,2]. |
| PubMedID- 26102729 | Objective: cardiovascular disease due to atherosclerosis is the leading cause of death worldwide. |
| PubMedID- 24890098 | The pathogenesis of atherosclerosis, the major cause of cardiovascular diseases (cvd), is multifactorial and therefore its treatment approaches and the ability to regress the plaque are complicated. |
| PubMedID- 24280698 | Overturning the deregulated epigenetic mechanisms may offer effective treatment strategy for many diseases including cardiovascular disease due to atherosclerosis and restenosis [3,4,9,10,11]. |
| PubMedID- 25555270 | atherosclerosis causing cardiovascular disease is the most common cause of death in the developed world. |
| PubMedID- 22421304 | Although expressed in atherosclerosis, its association with cardiovascular disease (cvd) in the community has not been reported. |
| PubMedID- 23843804 | Dyslipidemia is an established risk factor for atherosclerosis, which leads to cardiovascular diseases. |
| PubMedID- 22719926 | Metabolic syndrome, a consequence of complex interactions between liver and adipose tissue, is well established as a risk factor for atherosclerosis leading to cardiovascular diseases. |
| PubMedID- 23541658 | It is a key factor in the development of atherosclerosis, the main cause of vascular and cerebrovascular diseases, and is causally linked to kidney failure and dementia. |
| PubMedID- 24072353 | atherosclerosis, the leading cause of most cardiovascular disease, is a progressive multifaceted inflammatory disease characterized by extracellular matrix degradation and extensive remodeling of artery wall. |
| PubMedID- 23248190 | The association between impaired fpg and scd may be partly due to a clinically asymptomatic microvascular process as well as macrovascular disease with coronary atherosclerosis (4). |
| PubMedID- 20172495 | Vascular calcifications are feature of late stages of atherosclerosis and are associated with cardiovascular disease. |
| PubMedID- 25651913 | Accumulation of oxidised low density lipoprotein (oxldl) is a hallmark of atherosclerosis, the underlying cause of cardiovascular disease (cvd). |
| PubMedID- 23749050 | African american (aa) women are nearly twice as likely as non-hispanic white (nhw) women to develop atherosclerosis associated with cardiovascular disease. |
| PubMedID- 23671862 | Patients with diabetes often develop hypertension and atherosclerosis leading to cardiovascular disease. |
| PubMedID- 24082697 | A growing body of evidence also indicates that tobacco smoke is an independently associated with the insulin resistance and that the insulin resistant condition may contribute to the accelerated atherosclerosis that leads to excessive cardiovascular disease in the adult smokers. |
| PubMedID- 22328891 | Cardiovascular disease (cvd) due to atherosclerosis and thrombosis is the foremost cause of premature mortality and drop in disability-adjusted life years in europe, and is also increasingly common in developing countries [1, 2]. |
| PubMedID- 23329954 | Chronic renal failure (crf) is one of the important risk factors for cardiovascular disease due to accelerated atherosclerosis in the vascular –including the macrovascular and microvascular–bed [1]. |
| PubMedID- 21888685 | Patients with other chronic inflammatory diseases such as sle and ra experience excess cardiovascular disease, predominantly due to accelerated atherosclerosis, and this may occur in ssc also. |
| PubMedID- 26256660 | Lateral medullary infarction (lmi) is a vascular disease of the brainstem, and atherosclerosis of the vertebral artery (va) or posterior inferior cerebellar artery (pica) is the most common cause (50%). |
| PubMedID- 22962527 | Diabetes mellitus, a major risk factor for vascular diseases, is associated with accelerated atherosclerosis and a high rate of arterial thrombotic complications such as retinopathy, nephropathy and cerebrovascular disease. |
| PubMedID- 22888373 | Traditionally, keeping levels of low-density lipoprotein cholesterol(ldl-c) down and hdl-c up have been the goal of patients to prevent atherosclerosis that can lead to coronary vascular disease(cvd). |
| PubMedID- 23593564 | Homocysteine (hcy) is an intermediate in methionine metabolism.1 a large amount of epidemiological studies2 have confirmed that an increased plasma hcy concentration is an independent risk factor for atherosclerosis leading to cardiovascular diseases. |
| PubMedID- 23055758 | Cardiovascular disease, including atherosclerosis, is the leading cause of death in patients with diabetes worldwide; thus, it is a major medical concern. |
| PubMedID- 22792413 | atherosclerosis, the main cause of cardiovascular disease, is a multifactorial disorder where endothelial dysfunction and inflammation plays a critical role [3, 4]. |
| PubMedID- 23507055 | Cardiovascular disease due to accelerated atherosclerosis in systemic vasculitides. |
| PubMedID- 26210594 | This study was carried out on a high-risk group of patients suffering from clinical manifestations of atherosclerosis (enrolled patients with coronary atherosclerosis, cerebrovascular disease and peripheral vascular disease) [15]. |
| PubMedID- 20846238 | Homozygous patients have rapid development of atherosclerosis with death from cardiovascular disease even in childhood. |
| PubMedID- 22654868 | Together, these metabolic alterations increase the risk of hypertension, diabetes, and atherosclerosis, which all lead to cardiovascular disease and mortality from vascular events (van gaal et al., 2006). |
| PubMedID- 24688491 | atherosclerosis, the major cause of many cardiovascular diseases, is a chronic inflammatory condition. |
| PubMedID- 23438952 | Cardiovascular diseases (cvds), largely due to atherosclerosis, are the major causes of death in today's world. |
| PubMedID- 21297905 | (4) thus, it is generally accepted that oxidative modification of ldl followed by uptake of the modified ldl by macrophages and formation of cholesterol laden foam cells is important initial event of atherosclerosis leading to vascular diseases. |
| PubMedID- 23023895 | Cardiovascular disease due to atherosclerosis is a leading cause of death around the world, including singapore. |
| PubMedID- 25328922 | Objective: dyslipidemia, a disorder in the levels of cholesterol or lipoproteins in the plasma, is a feature of atherosclerosis, leading to cardiovascular disease. |
| PubMedID- 23635324 | atherosclerosis, the major cause of cardiovascular disease (cvd), is a chronic inflammatory condition with immune competent cells in lesions producing mainly pro-inflammatory cytokines. |
| PubMedID- 25592833 | Background: a few studies have shown an association between blood group alleles and vascular disease, including atherosclerosis, which is thought to be due to the higher level of von willebrand factor in these individuals and the association of blood group locus variants with plasma lipid levels. |
| PubMedID- 24924233 | Background: depression and cardiovascular diseases due to arteriosclerosis are both frequent and impairing conditions. |
| PubMedID- 25024545 | In addition, oral pathogens have been detected in atherosclerotic plaques, where they can play a role in the development and progression of atherosclerosis leading to coronary vascular disease. |
| PubMedID- 20528774 | The potential role of hoscn in human disease is poorly understood, but previous studies have provided evidence for a role for scn−-derived species in models of atherosclerosis, and humans with cardiovascular disease [9,19–21]. |
| PubMedID- 23843862 | In addition, a study on the use of repeatedly heated oil (a common practice in asian countries) concluded that it has the predisposing factor of atherosclerosis leading to cardiovascular diseases. |
| PubMedID- 20406324 | Complications of vascular diseases, including atherosclerosis, are the number one cause of death in western societies. |
| PubMedID- 26389124 | For example, low density-lipoprotein (ldl) oxidation triggers atherosclerosis leading to cardiovascular disease (aviram, 2000; van gaal et al., 2006). |
| PubMedID- 24363709 | Chronic kidney disease in humans is associated with a several times increased risk of developing cardiovascular disease because of accelerated atherosclerosis (4). |
| PubMedID- 21111933 | On the basis of this mechanism, chronic periodontitis has been suggested as a risk factor for cardiovascular diseases associated with atherosclerosis, bacterial endocarditis, diabetes mellitus, respiratory disease, preterm delivery, rheumatoid arthritis, and, recently, osteoporosis, pancreatic cancer, metabolic syndrome, renal diseases and neurodegenerative diseases such as alzheimer's disease. |
| PubMedID- 26322779 | It has been reported that there is an additive interaction between hyperglycemia and hypertension in terms of their effects on the adhesion of endothelial cells, which may cause atherosclerosis and lead to further cardiovascular disease or stroke [17]. |
| PubMedID- 24506844 | Patients with diabetes are at a high risk of artery atherosclerosis leading to cardiovascular disease (cvd), especially coronary heart disease (chd), which is the most common complication and the principal cause of death in type 2 diabetes patients. |