PedAM
Pediatric Disease Annotations & Medicines
| Disease | arteriosclerosis |
| Phenotype | |hypertension |
| Sentences | 70 |
| PubMedID- 26214690 | Amongst these disease states, coronary heart disease, stroke and peripheral vascular disease reflect to a substantive degree the effects of accelerated atherosclerosis in combination with dyslipidemia, hypertension and lifestyle factors such as smoking. |
| PubMedID- 26167316 | It has been fda-approved for treatment of hypertension, angina pectoris due to coronary artery atherosclerosis, migraine, hypertrophic subaortic stenosis, tachyarrhythmias, and certain tremors. |
| PubMedID- 23575736 | Although many of the cardiovascular sequelae of chronic hypertension are due to large artery atherosclerosis, an equal number are due to small artery dysfunction. |
| PubMedID- 21814209 | In addition, sodium is reabsorbed via the activated sympathetic nervous system, and reabsorption is specifically controlled by renal nerves.36, 37, 38 insulin, which increases in metabolic syndrome (obesity) and in the initial stages of type 2 diabetes, also acts to retain sodium by suppressing sodium loss into urine via renal tubules.39, 40, 41 obese people who are metabolically resistant to insulin are not resistant to renal tubular reabsorption of sodium by insulin.42 although prevention of sodium loss may once have conferred a selective advantage, ingestion of excessive amounts of sodium now results in chronic hypertension, a major cause of atherosclerosis in modern society. |
| PubMedID- 25712234 | Methods: 2,281 individuals in the multi-ethnic study of atherosclerosis without diabetes or hypertension, renal disease, or excess alcohol consumption underwent computed tomography (ct) for assessment of liver attenuation (marker of hepatic lipid content) and urinalysis (for albuminuria) at initial study visit, with assessment of incident and prevalent albuminuria by logistic regression in follow-up. |
| PubMedID- 24693449 | Hyperuricemia, per se, was found to be an independent predictor for atherosclerosis in patients with hypertension [33]. |
| PubMedID- 23124356 | The aim of this study was to investigate the association between myeloperoxidase (mpo) gene polymorphisms and carotid atherosclerosis (as) in patients with essential hypertension (eh). |
| PubMedID- 22937350 | The degeneration of the vascular wall due to atherosclerosis in association with hypertension is suggested as the pathogenic factor. |
| PubMedID- 26089898 | Diabetes, hypercholesterolemia, hypertension, and smoking, leading to atherosclerosis, and several other forms of vascular disease are associated with a reduced number and impaired functional activity of circulating epcs [14, 18, 31, 32, 38]. |
| PubMedID- 24274040 | In addition, childhood hypertension correlates with early atherosclerosis, impaired arterial compliance [8-10], cardiac structural changes [11], and additional risk factors for metabolic syndrome. |
| PubMedID- 23337395 | Aim: to evaluate the expression of atherosclerosis-associated genes in patients with hypertension and type 2 diabetes mellitus. |
| PubMedID- 26381729 | Recent studies suggested that uoc could serve as a novel biomarker for carotid atherosclerosis in patients with hypertension or metabolic syndrome [7, 8]. |
| PubMedID- 22849424 | Metabolic syndrome is a common multi-factorial disorder including abdominal obesity, insulin resistance, hypertension and dyslipidemia, leading to accelerated atherosclerosis and increased risk for diabetes [1,2]. |
| PubMedID- 25874197 | The patient had renal anemia and renal hypertension with carotid arteriosclerosis plaque. |
| PubMedID- 20345850 | Changes in vascular structure and function play important roles in the pathophysiology of hypertension, and together with atherosclerosis, in the complications of hypertension. |
| PubMedID- 25631547 | Cardiovascular disease is the number one cause of death in the world, mainly elicited by atherosclerosis together with hypertension [10]. |
| PubMedID- 21235741 | Levels of anti-pc are inversely associated with development of atherosclerosis in patients with established hypertension [32]. |
| PubMedID- 23984048 | During the past several years, abnormal but minimal urinary albumin excretion, well below the threshold that is commonly detected by standard urinalysis (so-called microalbuminuria), has been shown to be associated with an unfavourable metabolic risk profile and with extrarenal signs of target organ damage, such as left ventricular hypertrophy and carotid atherosclerosis in patients with primary hypertension [18, 19]. |
| PubMedID- 25709461 | In contrast, in people with hypothyroidism, atherosclerosis has been attributed to hypercholesterolemia, hypertension, and impaired endothelial function, leading to increased cardiovascular risk. |
| PubMedID- 22577415 | Lower serum levels of ghrelin have significant relationship with insulin resistance, type ii diabetes and hypertension that leads to increase in atherosclerosis.11, 12 few studies have been done on the effect of ghrelin on atherosclerosis in mets and some of the studies have reported the reverse correlation between ghrelin and atherosclerosis.13, 14 recently, measurement of carotid intima-media thickness (imt) using ultrasonography as a non-invasive method has been used for evaluation of vascular damage but few studies have assessed the effect of metabolic syndrome on carotid artery imt.15 it seems that assessment of the relationship between carotid imt and some inflammatory factors, ghrelin and adiponectin in mets, may predict asymptomatic vascular changes in patients with mets. |
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