PedAM
Pediatric Disease Annotations & Medicines
| Disease | west syndrome |
| Symptom | C0037769|infantile spasms |
| Sentences | 2 |
| PubMedID- 20398390 | infantile spasms are typical of west syndrome and are characteristically associated with so called "hypsarrhythmic" eeg. |
| PubMedID- 26125044 | Vigabatrin (vgb; γ-vinyl-gaba; sabrilr), an antiepileptic agent that irreversibly inhibits gaba-transaminase (gaba-t) (fig.1), is an fda-approved agent employed therapeutically in infantile spasms associated with west syndrome, secondary generalized seizures, and complex partial seizures.1,2 in a study of school age children who had received vgb as infants, riikonen and coworkers3 detected visual field defects (vfd) in one third, and further verified that the rate of vfds increased from 9% to 63% as the duration of vgb treatment had increased during infancy. |
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