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PedAM

Pediatric Disease Annotations & Medicines




Disease vitamin b12 deficiency
Symptom C0002871|anaemia
Sentences 11
PubMedID- 23998863 Mcv is unreliable as a screening parameter for the presumed diagnosis of macrocytic anaemia, which is associated with vitamin b12 deficiency.
PubMedID- 24599434 Megaloblastic anaemia due to vitamin b12 deficiency is rare in childhood.
PubMedID- 20573208 Background: pernicious anaemia is undeniably associated with vitamin b12 deficiency, but the association between subnormal vitamin b12 concentrations and anaemia in older people is unclear.
PubMedID- 21868809 Although pernicious anaemia is associated with severe vitamin b12 deficiency, evidence of an association between subnormal vitamin b12 and anaemia in older persons in the general population is limited and inconclusive.
PubMedID- 22764443 anaemia due to vitamin b12 deficiency (32.2%), acute leukaemia (23.7%) and aplastic anaemia (15.2%) were the main causes of pancytopenia.
PubMedID- 25954799 It sometimes causes vitamin b12 deficiency leading to macrocytic anaemia or peripheral neuropathy.
PubMedID- 22489214 Water-soluble vitamins such as folate are important for reducing the risk of both neural tube defects (ntds) (13) heart disease by lowering homocysteine levels (14), whilst vitamin b12 deficiency is associated with pernicious anaemia in infants (15) and elderly populations and patients with intestinal disease (16, 17).
PubMedID- 22481896 Because high doses of folic acid are able to correct the anaemia associated with vitamin b12 deficiency, high intakes could delay the diagnosis of the latter vitamin by masking its deficiency, which could lead to irreversible neurological damage/higher risk of memory impairment (47).
PubMedID- 26320356 In this case report we present a 39-year-old male vegan with severe macrocytic anaemia due to vitamin b12 deficiency as well as secondary hyperparathyroidism due to severe vitamin d deficiency.
PubMedID- 24401542 Blood tests showed macrocytic anaemia due to vitamin b12 deficiency with coombs negative haemolysis.
PubMedID- 21396086 Individuals with vitamin b12 deficiency associated with macrocytic anaemia may present with peripheral neuropathy (sensory disturbances in the extremities such as tingling and numbness, and impaired vibration and joint position sense) and myelopathy that can progress, if untreated, to severe motor problems 5.

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