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PedAM

Pediatric Disease Annotations & Medicines




Disease varicocele
Symptom C0021359|infertility
Sentences 31
PubMedID- 25890347 Background: the etiology of varicocele, a common cause of male factor infertility, remains unclear.
PubMedID- 25343526 We conclude that locally secreted igf-i in the semen may be involved in the pathophysiology of infertility in patients with varicocele or semen.
PubMedID- 25405715 varicocele is commonly associated with male infertility because it impairs normal sperm morphology and activity.
PubMedID- 23926568 In addition, asas do not play an important role in the infertility of men with varicocele (9).
PubMedID- 23421634 It is concluded that there is an association between sperm mtdna 4977-bp deletion and varicocele-induced infertility in the population studied.
PubMedID- 23165400 Of these, current evidence suggests that oxidative stress is the central element contributing to infertility in men with varicocele, to which the testis responds by way of heat stress, ischaemia or production of vasodilators, such as nitric oxide.
PubMedID- 25246910 We assessed infertile men who were referred to us and chose only those for whom infertility was due to varicocele, which is defined as the enlargement of the venous plexus of spermatic tone.
PubMedID- 24716087 Even though the cases of testicular arteriovenous communication are rare, cases of male infertility due to oligospermia and varicocele should be investigated with the help of doppler ultrasound and arteriogram to rule out any vascular anomaly such as described in the present case.
PubMedID- 21105479 As these genetic alterations are associated with infertility, genetic screening in patients with varicocele may represent a useful tool for diagnosis and prognosis of some cases of male infertility.
PubMedID- 23661519 Background: varicocele associated with infertility has been recognized for years.
PubMedID- 21681090 Purpose of review: the increased risk of infertility in men with varicocele is well established.
PubMedID- 23346528 Abnormal semen parameters in infertility patients with varicocele were first reported in 1965. at the same time, a connection between varicoceles and reduced sperm count and motility, testicular size and histological changes were also proposed .
PubMedID- 24236235 Hundred and six patients with varicocele associated with male infertility over a 5-year period were included into the study.
PubMedID- 25967606 Methods: a total of 80 male infertility patients with varicocele were recruited from april 2011 to february 2012.
PubMedID- 26246871 varicocele-induced infertility in animal models.
PubMedID- 20039234 Ovarian varicocele may be associated with infertility in some patients.
PubMedID- 23227502 Aim: to improve the results of treatment for male infertility in patients with varicocele and to evaluate the efficiency of microsurgical varicocelectomy performed by the same surgeon in a large group of patients.
PubMedID- 25677140 Our previous study has shown a possible relationship between the gstt1 null genotype and the susceptibility to male infertility in patients with varicocele, and we found that the gstt1 positive genotype improved the antioxidant capacity, reduced the levels of ros in seminal plasma, and prevented injury caused by ros to the sperm dna in infertile patients with varicocele.8 a japanese group has reported that after varicocelectomy, the gstt1 positive genotype is associated with an improvement in the seminal findings of infertile patients with varicocele.9 in recent clinical practice, we have also found that patients with the gstt1 positive genotype have better responses to varicocelectomy than do patients with the gstt1 null genotype (data not shown).
PubMedID- 20495699 Therefore, studies on the association of a varicocele with male infertility are still needed to improve our understanding of the correlation between a varicocele and male infertility.
PubMedID- 22809864 varicocele, a cause of male infertility, occurs in nearly 40% of infertile males.
PubMedID- 23658861 To date, general indications for treatment of varicocele are limited in patients with proven infertility, clinical palpable varicocele, and abnormal semen characteristics.
PubMedID- 23441453 Conclusion: infertility patients with varicocele have psychological disorders, which are particularly associated with the frequency of the patients' clinic visit and the severity of their testis disorders.
PubMedID- 25242995 The high incidence of varicocele in men with secondary infertility and the fact that varicocele generally develops at the time of puberty, suggest that the presence of varicocele can cause a progressive decline in fertility.
PubMedID- 25705240 Two recent studies have shown that the incidence of varicocele with secondary infertility is significantly greater than primary infertility .
PubMedID- 26568883 To establish the extent of varicocele as the cause of infertility in men and compare the various techniques of treatment.
PubMedID- 23274391 The higher frequency of varicocele in men with infertility has drawn attention and resulted in increased research at the molecular level towards treatments.
PubMedID- 26246877 Different inclusion criteria in each study.the infertile populations in different studies maybe included various categories of infertility suchas patients with varicocele or infection in genitaltract and also different semen parameters, for exampleazoospermia or oligozoospermia (10, 21,22).
PubMedID- 24582535 Male infertility due to varicocele may be associated with protamine deficiency and sperm dna damage.
PubMedID- 23754533 Accumulating evidence suggests that varicocele, long associated with male infertility, is also a risk factor for low testosterone levels.
PubMedID- 22747653 In conclusion, cox enzymes may possess a biological relevance in the pathogenesis and/or maintenance of male factor infertility associated with varicocele and dm, and may be considered additional molecular markers for the diagnosis of male infertility disorders.
PubMedID- 23634797 In conclusion, the data suggest that pi3k may play a role in the maintenance of male factor infertility associated with varicocele, and it may be further exploited as an additional molecular marker for the diagnosis of male infertility disorders.

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