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PedAM

Pediatric Disease Annotations & Medicines




Disease vaccinia
Symptom C0021311|infections
Sentences 6
PubMedID- 24696488 Human monocytic and professional antigen-presenting cells have been reported only to exhibit abortive infections with vaccinia virus (vacv).
PubMedID- 23935480 For example, clec9a (also known as dngr-1) was recently shown to facilitate antigen cross-presentation, a function required for the control of infections with vaccinia virus and herpes simplex virus .
PubMedID- 24789223 Increased recognition and characterization of enzootic human infections with vaccinia have, respectively, also been made in south america and eurasia 7.
PubMedID- 21994637 The susceptibility of immunocompetant mice to lethal or non-lethal infections with vaccinia virus or cowpox virus provides an important model system.
PubMedID- 21658738 Cowpox virus infection induces interleukin-10 (il-10) production from mouse bone marrow-derived dendritic cells (bmdcs) or cells of the mouse macrophage line (raw264.7) at about 1800 pg/ml, whereas infections with vaccinia virus (strains wr or mva) induced much less il-10.
PubMedID- 20126444 Additionally, the new anti-poxviral drugs have been used to treat rare cases of runaway infections with the live vaccinia vaccine itself.

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