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PedAM

Pediatric Disease Annotations & Medicines




Disease tuberculosis
Symptom C0235378|hepatotoxicity
Sentences 19
PubMedID- 21418817 The associations of polymorphism of n-acetyltransferase 2 gene is associated with antituberculosis drug-induced hepatotoxicity in tuberculosis patients.
PubMedID- 20409289 Data on antituberculosis drug-induced hepatotoxicity in sub saharan africa are limited, probably because liver function tests are not carried out routinely during tuberculosis treatment in most african countries.
PubMedID- 21706943 To evaluate the rate of and risk factors for hepatotoxicity in tuberculosis (tb) and human immunodeficiency virus type 1 (hiv-1) co-infected patients while receiving non-nucleoside reverse transcriptase inhibitor (nnrti)-based antiretroviral therapy (art) and a rifampicin (rmp)-containing anti-tb regimen.
PubMedID- 20819434 Genetic polymorphisms of cytochrome p450 and glutathione s-transferase associated with antituberculosis drug-induced hepatotoxicity in chinese tuberculosis patients.
PubMedID- 26202867 Antituberculosis drug-induced hepatotoxicity (atdh) is a serious concern in tuberculosis treatment and management of hepatotoxicity.
PubMedID- 26377643 Isoniazid-induced hepatotoxicity in children with latent tuberculosis infection.
PubMedID- 25271170 Association of the cyp2b6 gene with anti-tuberculosis drug-induced hepatotoxicity in a brazilian amazon population.
PubMedID- 22947533 Nat2 genetic polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in chinese community population.
PubMedID- 20136661 Background: triple nucleoside reverse transcriptase inhibitor regimens have advantages as first-line antiretroviral therapy (art), avoiding hepatotoxicity and interactions with anti-tuberculosis therapy, and sparing two drug classes for second-line art.
PubMedID- 21404653 "management of hepatotoxicity during antituberculosis chemotherapy" was published by the japanese society for tuberculosis (jst) in 2006.
PubMedID- 25525805 Impact of glutathione s-transferase m1 and t1 on anti-tuberculosis drug-induced hepatotoxicity in chinese pediatric patients.
PubMedID- 22283902 N-acetyltransferase 2 polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity in caucasians.
PubMedID- 22808112 Unexpectedly low (2%) anti-tuberculosis drug-induced hepatotoxicity was also reported in hiv-infected pulmonary tuberculosis patients from malawi .
PubMedID- 22943824 Methods: genetic polymorphisms of ces1 in 473 tuberculosis patients with or without hepatotoxicity (200:273) after antituberculosis chemotherapy were analyzed by pcr-massarray.
PubMedID- 25671954 Conclusion: the study showed that the risk of development of drug-induced hepatotoxicity following treatment with first line anti-tuberculosis treatment increased with the age of the patient.
PubMedID- 23475203 These results provide novel insight into the mechanism of rifampicin and isoniazid–induced liver injury that may be applied to clinical management of the hepatotoxicity associated with tuberculosis chemotherapy.
PubMedID- 21047300 Among patients, anti-tuberculosis induced hepatotoxicity was more frequent in slow acetylators in comparison with fast acetylators in iranian tuberculosis patients.
PubMedID- 23743313 hepatotoxicity due to first-line anti-tuberculosis drugs: a five-year experience in a taiwan medical centre.
PubMedID- 24607341 The association between cyp2e1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis.

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