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PedAM

Pediatric Disease Annotations & Medicines




Disease thalassemia
Symptom C0024530|malaria
Sentences 4
PubMedID- 23853772 The protection of α+-thalassemia against malaria might be due to higher susceptibility of homozygotes to malaria in early life that immunize these individuals and make them resistance to malaria later 7.
PubMedID- 26174819 Interestingly, it is of note for the coexistence of malaria with only α-thalassemia-2 but not α-thalassemia-1, the commonly found thalassemia type in southeast asia.
PubMedID- 22133230 Recent studies in kenya and ghana have shown that individuals who inherit two malaria-protective genetic disorders of haemoglobin-alpha(+) thalassaemia and sickle cell trait-experience a much lower level of malaria protection than those who inherit sickle cell trait alone.
PubMedID- 25915902 In a conclusion, a high frequency of alleles such as g6pd deficiency, hbs, hbc and α-thalassemia associated with malaria resistance were present on bioko island.

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