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PedAM

Pediatric Disease Annotations & Medicines




Disease thalassemia
Symptom C0002871|anaemia
Sentences 6
PubMedID- 22973867 There remained a significant difference in anaemia among those with normal α+-thalassaemia genotype (43.0%), heterozygotes (53.5%) and homozygotes (67.7%, chi-square trend p = 0.012) (table 4).
PubMedID- 22413027 Interactions of many factors that co-exist such as poor dietary intake, increased demands (e.g., growth), parasitic infections, socioeconomic causes and genetic factors (e.g., thalassaemia) may be causes of anaemia and ida.
PubMedID- 19912309 The third had an intermediate alpha-thalassaemia with considerable anaemia caused by an as yet unknown polyadenylation site (aataaa>aataac) mutation in combination with a common rw deletion masked by a common hb c beta6(a3)glu-->lys heterozygosity.
PubMedID- 24025420 Third, as the samples were submitted only for α thalassaemia screening, other causes of microcytic anaemia such as iron deficiency were not determined.
PubMedID- 22089611 The presence of anaemia due to alpha-thalassaemia does not require any treatment in general3.
PubMedID- 24431329 Haemoglobinopathy workup revealed no clinically relevant haemoglobinopathy (normal hb-electrophoresis, normal hba, hbf, hba2), but genetic data (see below) and the microcytic hypochromic anaemia were compatible with α thalassaemia trait (genotype –/αα).

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