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PedAM

Pediatric Disease Annotations & Medicines




Disease temporal lobe epilepsy
Symptom C1504404|hippocampal sclerosis
Sentences 142
PubMedID- 24903633 Distinct functional and structural mri abnormalities in mesial temporal lobe epilepsy with and without hippocampal sclerosis.
PubMedID- 21150756 Presence of temporal gray-white matter abnormalities does not influence epilepsy surgery outcome in temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 21621747 Whether decreased calbindin expression is unique to the hippocampal sclerosis associated with cryptogenic temporal lobe epilepsy, or also occurs in tumor- or malformation-related epilepsy, is unknown.
PubMedID- 21746814 hippocampal sclerosis in temporal lobe epilepsy: findings at 7 t(1).
PubMedID- 24146813 In human temporal lobe epilepsy with hippocampal sclerosis, dysfunction of the mirna processing machinery has been reported .
PubMedID- 23613762 Background: where neurocysticercosis (ncc) is endemic, chronic calcified neurocysticercosis (cncc) can be observed in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis (mtle-hs).
PubMedID- 23153868 Effect of patient sex on white matter alterations in unilateral medial temporal lobe epilepsy with hippocampal sclerosis assessed by diffusion tensor imaging.
PubMedID- 25727907 Mesial temporal lobe epilepsy with hippocampal sclerosis, (mtle-hs) is a well characterized disorder which associates electroclinical features suggestive of seizure onset in the mesial or limbic structures of the temporal lobe, and hippocampal sclerosis.
PubMedID- 24002650 Febrile seizures (fs) are recognized as an antecedent to the development of temporal lobe epilepsy with hippocampal sclerosis (tle-hs), but it is unclear whether prolonged fs are a direct cause of tle-hs.
PubMedID- 23667120 Early-onset right mesial temporal lobe epilepsy with hippocampal sclerosis is the key substrate determining a severe deficit in recognizing emotional facial expressions and decision-making.
PubMedID- 23055518 The normal subcortical white matter was obtained from patients with drug-resistant temporal lobe epilepsy associated with hippocampal sclerosis who underwent surgery (fig.
PubMedID- 24061200 This was assessed in three cohorts of ethnically matched south indian ancestry: mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) (prototype of aed-resistant epilepsy syndrome), juvenile myoclonic epilepsy (prototype of aed-responsive epilepsy syndrome), and nonepilepsy controls.
PubMedID- 20533558 Studies of in mesial temporal lobe epilepsy (mtle) patients with hippocampal sclerosis (hs) have reported reductions in both functional and structural connectivity between hippocampal structures and adjacent brain regions.
PubMedID- 20307957 Objective: the seizure network may be different between temporal lobe epilepsy with hippocampal sclerosis (tle+hs) and without hs (tle-hs).
PubMedID- 24680551 Purpose: there is a lack of information from south america regarding factors that predict the clinical outcomes of patients treated medically for mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs).
PubMedID- 20888264 Doublecortin (dcx) immunoreactivity in hippocampus of chronic refractory temporal lobe epilepsy patients with hippocampal sclerosis.
PubMedID- 23804486 Distinct increased metabotropic glutamate receptor type 5 (mglur5) in temporal lobe epilepsy with and without hippocampal sclerosis.
PubMedID- 22085881 Impaired egocentric memory and reduced somatosensory cortex size in temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 22277455 Surgical treatment should be considered for drug resistant patients, especially for those suffering from temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 21099715 Analysis of reoperation in mesial temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 24014518 Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 24908373 Short-term cognitive changes after surgery in patients with unilateral mesial temporal lobe epilepsy associated with hippocampal sclerosis.
PubMedID- 21303859 The endocannabinoid system modulates neuronal excitability, protects neurons against hyperexcitability and is involved in epileptogenesis in animal models of mesial temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 25955498 Interhemispheric microstructural connectivity in bitemporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 24586633 In the present study we inquired the role of multidrug transporters abcb1 and abcg2 variants in determining aed-resistance and susceptibility to epilepsy in three well-characterized cohorts comprising of mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) (prototype for aed-resistant epilepsy); juvenile myoclonic epilepsy (jme) (prototype for aed-responsive epilepsy); and healthy non-epileptic controls, in 738 subjects of malayalam speaking south indian ancestry.
PubMedID- 23908665 In genetic studies, homozygosity for the il-1β-511 allele 2, which is thought to be an inducer of il-1β, was overrepresented in temporal lobe epilepsy patients with hippocampal sclerosis when compared to control subjects18).
PubMedID- 26354165 Neuroimaging observations linking neurocysticercosis and mesial temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 24440288 Mitochondrial dna profiling via genomic analysis in mesial temporal lobe epilepsy patients with hippocampal sclerosis.
PubMedID- 26162046 Gamma knife radiosurgery for recurrent or residual seizures after anterior temporal lobectomy in mesial temporal lobe epilepsy patients with hippocampal sclerosis: long-term follow-up results of more than 4 years.
PubMedID- 26106557 All patients have medial temporal lobe epilepsy with unilateral hippocampal sclerosis according to mri criteria with ipsilateral seizure onset during non-invasive/invasive eeg monitoring and underwent epilepsy surgery (selective amygdalohippocampectomy) afterwards.
PubMedID- 25832914 Methods: functional imaging risk maps were generated for 14 patients suffering from dominant temporal lobe epilepsy 7 with hippocampal sclerosis (hs), 7 with various lesions and used for neuronavigation-guided tailored resection.
PubMedID- 26300534 Functional substrate for memory function differences between patients with left and right mesial temporal lobe epilepsy associated with hippocampal sclerosis.
PubMedID- 26277098 Mesial temporal lobe epilepsy (mtle) with hippocampal sclerosis (hs) is the most common epilepsy syndrome in adults and is often associated with pharmacoresistance .
PubMedID- 21377331 Introduction: diffusion tensor imaging (dti) techniques demonstrated diffuse bilateral temporal and extra-temporal abnormalities of white matter in patients presenting mesial temporal lobe epilepsy with hippocampal sclerosis (hs).
PubMedID- 25206700 Therefore, further studies addressing the mechanisms of mesial temporal lobe epilepsy with hippocampal sclerosis may help us understand the underlying pathogenesis of drug-resistant epilepsy.
PubMedID- 26132287 Aabbreviations: ilae = international league against epilepsy; mtle-hs = mesial temporal lobe epilepsy with hippocampal sclerosis; gtcs = generalized tonic-clonic seizures.
PubMedID- 22937234 Characterization of the gene expression profile of human hippocampus in mesial temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 21933182 Purpose: metabolic changes have been described in the nonepileptic temporal lobe of patients with unilateral mesiotemporal lobe epilepsy (mtle) associated with hippocampal sclerosis (hs).
PubMedID- 24339586 Drug resistant temporal lobe epilepsy with hippocampal sclerosis has also been described with le associated with vgkc-abs, in a 13-year-old girl.
PubMedID- 23329953 The most common class of symptomatic epilepsies is the mesial temporal lobe epilepsy (mtle) frequently associated with hippocampal sclerosis .
PubMedID- 21439855 Purpose: to investigate the frequency and patterns of headache in a well-defined and homogeneous group of mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) patients.
PubMedID- 25052709 Objective: to assess changes in the relative lateralization of interictal epileptiform discharges (ieds) and interictal eeg prognostic value in terms of surgical outcome between periods with full medication (fmp) and reduced medication (rmp) in patients with temporal lobe epilepsy (tle) associated with hippocampal sclerosis (hs).
PubMedID- 23776122 Of 71 acute lymphoblastic leukemia survivors at our hospital over the past 10 years, 2 children developed mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs).
PubMedID- 21946422 However, we also need to consider early surgical treatment for temporal lobe epilepsy with hippocampal sclerosis.
PubMedID- 23127969 Currently, temporal lobe epilepsy associated with hippocampal sclerosis is regarded as a progressive disorder.
PubMedID- 23530853 Among epilepsy-associated non-neoplastic lesions, mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) and malformation of cortical development (mcd), including focal cortical dysplasia (fcd), are the two most frequent causes of drug-resistant focal epilepsies, constituting about 50% of all surgical pathology of epilepsy.
PubMedID- 24766708 Thus, the aim of this study was to compare the cerebral areas involved in eeg oscillations versus fmri signal patterns during a working memory (wm) task in normal controls and patients with refractory mesial temporal lobe epilepsy (mtle) associated with hippocampal sclerosis (hs).
PubMedID- 25306064 Recent observations suggest that neurocysticercosis (ncc) might act as an initial precipitating injury (ipi) causing mesial temporal lobe epilepsy associated with hippocampal sclerosis (mtle-hs).
PubMedID- 25598219 Background and purpose: to evaluate if an automatic magnetic resonance imaging (mri) processing system may improve detection of hippocampal sclerosis (hs) in patients with mesial temporal lobe epilepsy (mtle).
PubMedID- 20738385 Purpose: around one-third of patients undergoing temporal lobe surgery for the treatment of intractable temporal lobe epilepsy with hippocampal sclerosis (hs) fail to become seizure-free.

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