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PedAM

Pediatric Disease Annotations & Medicines




Disease temporal lobe epilepsy
Symptom C0149958|complex partial seizures
Sentences 3
PubMedID- 25842270 This model that was developed by goddard (1967) became known as the kindling model for epileptogenesis and has become a widely used model for temporal lobe epilepsy with complex partial seizures.
PubMedID- 22174508 However, the posterior parietal region is connected to the cingulate gyrus, insula, and parahippocampal gyrus so that seizure propagation to these structures may well imitate complex partial seizures of temporal lobe epilepsy.
PubMedID- 24288602 temporal lobe epilepsy usually presents with simple and/or complex partial seizures, although the underlying pathology may be any of a wide spectrum of pathological entities, such as hippocampal sclerosis, low grade glial tumors (dysembryoplastic neuroepithelial tumor, ganglioglioma, and oligodendroglioma), neuronal migrational disorders (cortical dysplasia), and vascular lesions (cavernous malformation and arteriovenous malformation), while in a significant number of cases no structural abnormalities can be found despite the exhausting imaging workup.

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