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PedAM

Pediatric Disease Annotations & Medicines




Disease severe combined immunodeficiency
Symptom C0039538|teratomas
Sentences 4
PubMedID- 20075393 The vitrified stem cells continued to express markers of pluripotency and formed teratomas in mice with severe combined immunodeficiency, confirming the pluripotency of vitrified-warmed human embryonic stem cell clumps.
PubMedID- 22548356 Furthermore, cdk2ap2(tr/tr) mescs were unable to form teratomas in severe combined immunodeficiency (scid) mice.
PubMedID- 22128806 However itscs do not form teratomas in severe combined immunodeficient mice.
PubMedID- 21565833 Methods and results: the hipscs generated by episomal vectors generated teratomas in severe combined immunodeficient mice, readily formed embryoid bodies, and differentiated into cardiomyocytes with comparable efficiency to human embryonic stem cells.

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